Click here to switch to the map view.

The map label for this gene is xdhA [C]

Identifier: 182680267

GI number: 182680267

Start: 3821192

End: 3823519

Strand: Reverse

Name: xdhA [C]

Synonym: Bind_3367

Alternate gene names: 182680267

Gene position: 3823519-3821192 (Counterclockwise)

Preceding gene: 182680268

Following gene: 182680256

Centisome position: 91.69

GC content: 62.89

Gene sequence:

>2328_bases
ATGGCTAGACTGGGCTCTATGCAAAATGCCGCGATGATCCAGTCGCGGCGCAGCTTCCTCGTTACTATGGCGGGCGCGAG
CCTTGCTTTCGGCTTTACGCGCGGAGCCGGCGCGGCCATAGACCCCGCCACCGCTGATGGGGTGCCACCCAACGCTGTCG
GCACCCTGTTCGAGCCTTCGCTCTGGTATTCCATCGACAGTACCGGCACGGTTACGGTCAATATCATCCGCGCGGAAATG
GGCCAGCATGTGGGGACCGCGCTCGCCCGCATCCTCGCCGATGAACTCGAAGCCGATTGGAAGACTGTCCGGATCACCCA
TGTCGATACGGATCCGAAATGGGGCTTGATGGTTACCGGCGGGAGCTGGTCGGTCTCCCAAACTTGGCCGATCTTCAGCC
GCGCCGGTGCCGCCGGGCGTCTCGCGCTGATCGAGGCGGGCGCCGCGCTTTTGAAGGTCGCGCCGAGCGCCTGCGTTGCG
CGGGACGGCAAGGTCTATGCCGGCACCCAATCGATCGCCTATGGCGATATTATTGCGCAGGGTCCTCACTTCCGCCAATT
CTCGCCTGAGGATCTCGACAAACTGACGCTCAAGCCCGTGTCCGAACGCCGGCTGATCGGCAAACCGGTCACGGCGCTCG
ATATTCCGGCCAAGACCAATGGCGAGGCCGTCTATGGCATCGATGCGAAAGTGCCAGGCATGGTGCACGCCCGGCCCAAA
ATTCCGCCGACCCGCTATGGCTCCAAGGTCGTTTCGGTCGATGACAGTGCCGCGCGCAAGGTCAAGGGCTATTTGCAGAG
CCTCGTCATCGACGACCCCTCAGAGACCGTGCCCGGCTGGGTCCTGGTGATCGCGGAATCGACTTTTGCCGCGATGCGCG
CCGCTGATCTCGTCAAGGTTACGTGGAGCGCCGGTCCCACGGCCCATATCTCCGAAAAGGAGATTCAAGATCACGCAGTC
GAACAGATCGCCAGGCGAGATAATGGCGTTCTCCTTGAACTTGGCGGCGCCAAGGGCGTGGACGTCGCCAAGCCCGCTTT
CGAGGCGGCGGCTTCGACCCTGGAACAGACCTACACGACCGCAACCGTCCTGCATTTCCAGCTTGAACCGTTGAACGCTT
TGGCTTTCGAAAAGGACGGCATTTTCGAAATCCATACGGGCAATCAATGGCAGAGCCTGATCCTGCCAGTGCTGGCCAAG
GCCCTGCAACGGCCGCAGGAGAGCATTGTTCTGCGTTCCTATATGCTCGGCGGTGGTTTCGGCCGCAGACTTAATGGTGA
TTATGCCGTGCCGGCGGCCTTGGCGGCCAAGGCGCTGGGTCGCCCGGTCAAAGTGGTGCTGACTCGCCAAGACGATGCTT
TGTTCGACTCAGTGCGCTCGCCTTCTGTCCAGACTGTGCGTATGGCATTCGACGCGGCGAACAAAGTGACCGGCATGGAG
CATCATGCGGCGGCCGGCTGGCCGACCGAGGTCATGGCGCCCGCTTTCATGCCCAAGGGACAGGAGGGCAAACCCTTCGA
TCCTTTCGCCATAGCGGGGGCGGATCATTGGTATGATGTCGGCCCGCAACTCGTGCGTGCTCTCTCCAATGATCTCGCCA
ATGCGACCTTCCGGCCTGGCTGGCTGCGCTCGGTCGGTCCGGGCTGGATCAATTGGGCGCTCGAAAGTTTCATGGACGAG
GCCGCTCTCCATGTGAAGATGGACCCGTTGGCGTTCCGGCTGAATTTGCTCAATGGCAAGGGACAGAACGACAATGCGGG
CTCGGCTCCTGTGTCCGTGGGGGGCGCCTCGCGACAGGCGGAGGTGATCCGCCGCGCGGCGCAGCGCGCCGGCTGGGGGC
AGGCGCTGCCGGCCGATACCGCTTTGGGCCTTGCGACGAGTTTCGGCCAGGAACGTGAAATGCCGACCTGGATGGCCTGC
GCGGCGCGTGTCCATGTCGATCGCAAGACCGGCCAGGTGCGGGTGGAAAAGCTGACGATCGTGACCGATGCGGGCACGAT
CGTCGATCCGGATGGCGCACGCGCCCAGACGGAGGGCGCGACGCTCTGGGGCCTTAGCATGGCCTTGCACGAGGGGACGC
TTTTTGAAAAGGGCCAGGTCCGCGACACCAATCTCGACACTTACACGCCTTTGCGGATCGATGAGACGCCGGAACTCGAC
ATCAGCTTCGTCGAGAGTACGGAAATGCCGGTTGGCCTTGGCGAGCCGGCGACGACCGTGATCGCGCCCGCCATCGGCAA
TGCCATTTTCGCCGCCGTGGGCGTCCGGTTACGGCATTTGCCGATCACTTCGGAGGCCGTGCTGTCTGGCCTCAAGACTT
TGGGGTGA

Upstream 100 bases:

>100_bases
GATGCCGTGATGACCGGCAATCTCTGTCGTTGCATGACCTATGTGCGCATTCGCGCGGCCATCAAGCAGGCGGCCGCCGC
GCTGCGGGGAGAAGTCACCA

Downstream 100 bases:

>100_bases
ATGGAATTGATGGCGGTAGTATCCACCCTCATTGAAGCGCGACTCGTCGCGGTTCAATGAGAGTGGATACGGTTTAAAAA
ATGACGTATCGAGAATCTGT

Product: aldehyde oxidase and xanthine dehydrogenase molybdopterin-binding protein

Products: NA

Alternate protein names: ALDH [H]

Number of amino acids: Translated: 775; Mature: 774

Protein sequence:

>775_residues
MARLGSMQNAAMIQSRRSFLVTMAGASLAFGFTRGAGAAIDPATADGVPPNAVGTLFEPSLWYSIDSTGTVTVNIIRAEM
GQHVGTALARILADELEADWKTVRITHVDTDPKWGLMVTGGSWSVSQTWPIFSRAGAAGRLALIEAGAALLKVAPSACVA
RDGKVYAGTQSIAYGDIIAQGPHFRQFSPEDLDKLTLKPVSERRLIGKPVTALDIPAKTNGEAVYGIDAKVPGMVHARPK
IPPTRYGSKVVSVDDSAARKVKGYLQSLVIDDPSETVPGWVLVIAESTFAAMRAADLVKVTWSAGPTAHISEKEIQDHAV
EQIARRDNGVLLELGGAKGVDVAKPAFEAAASTLEQTYTTATVLHFQLEPLNALAFEKDGIFEIHTGNQWQSLILPVLAK
ALQRPQESIVLRSYMLGGGFGRRLNGDYAVPAALAAKALGRPVKVVLTRQDDALFDSVRSPSVQTVRMAFDAANKVTGME
HHAAAGWPTEVMAPAFMPKGQEGKPFDPFAIAGADHWYDVGPQLVRALSNDLANATFRPGWLRSVGPGWINWALESFMDE
AALHVKMDPLAFRLNLLNGKGQNDNAGSAPVSVGGASRQAEVIRRAAQRAGWGQALPADTALGLATSFGQEREMPTWMAC
AARVHVDRKTGQVRVEKLTIVTDAGTIVDPDGARAQTEGATLWGLSMALHEGTLFEKGQVRDTNLDTYTPLRIDETPELD
ISFVESTEMPVGLGEPATTVIAPAIGNAIFAAVGVRLRHLPITSEAVLSGLKTLG

Sequences:

>Translated_775_residues
MARLGSMQNAAMIQSRRSFLVTMAGASLAFGFTRGAGAAIDPATADGVPPNAVGTLFEPSLWYSIDSTGTVTVNIIRAEM
GQHVGTALARILADELEADWKTVRITHVDTDPKWGLMVTGGSWSVSQTWPIFSRAGAAGRLALIEAGAALLKVAPSACVA
RDGKVYAGTQSIAYGDIIAQGPHFRQFSPEDLDKLTLKPVSERRLIGKPVTALDIPAKTNGEAVYGIDAKVPGMVHARPK
IPPTRYGSKVVSVDDSAARKVKGYLQSLVIDDPSETVPGWVLVIAESTFAAMRAADLVKVTWSAGPTAHISEKEIQDHAV
EQIARRDNGVLLELGGAKGVDVAKPAFEAAASTLEQTYTTATVLHFQLEPLNALAFEKDGIFEIHTGNQWQSLILPVLAK
ALQRPQESIVLRSYMLGGGFGRRLNGDYAVPAALAAKALGRPVKVVLTRQDDALFDSVRSPSVQTVRMAFDAANKVTGME
HHAAAGWPTEVMAPAFMPKGQEGKPFDPFAIAGADHWYDVGPQLVRALSNDLANATFRPGWLRSVGPGWINWALESFMDE
AALHVKMDPLAFRLNLLNGKGQNDNAGSAPVSVGGASRQAEVIRRAAQRAGWGQALPADTALGLATSFGQEREMPTWMAC
AARVHVDRKTGQVRVEKLTIVTDAGTIVDPDGARAQTEGATLWGLSMALHEGTLFEKGQVRDTNLDTYTPLRIDETPELD
ISFVESTEMPVGLGEPATTVIAPAIGNAIFAAVGVRLRHLPITSEAVLSGLKTLG
>Mature_774_residues
ARLGSMQNAAMIQSRRSFLVTMAGASLAFGFTRGAGAAIDPATADGVPPNAVGTLFEPSLWYSIDSTGTVTVNIIRAEMG
QHVGTALARILADELEADWKTVRITHVDTDPKWGLMVTGGSWSVSQTWPIFSRAGAAGRLALIEAGAALLKVAPSACVAR
DGKVYAGTQSIAYGDIIAQGPHFRQFSPEDLDKLTLKPVSERRLIGKPVTALDIPAKTNGEAVYGIDAKVPGMVHARPKI
PPTRYGSKVVSVDDSAARKVKGYLQSLVIDDPSETVPGWVLVIAESTFAAMRAADLVKVTWSAGPTAHISEKEIQDHAVE
QIARRDNGVLLELGGAKGVDVAKPAFEAAASTLEQTYTTATVLHFQLEPLNALAFEKDGIFEIHTGNQWQSLILPVLAKA
LQRPQESIVLRSYMLGGGFGRRLNGDYAVPAALAAKALGRPVKVVLTRQDDALFDSVRSPSVQTVRMAFDAANKVTGMEH
HAAAGWPTEVMAPAFMPKGQEGKPFDPFAIAGADHWYDVGPQLVRALSNDLANATFRPGWLRSVGPGWINWALESFMDEA
ALHVKMDPLAFRLNLLNGKGQNDNAGSAPVSVGGASRQAEVIRRAAQRAGWGQALPADTALGLATSFGQEREMPTWMACA
ARVHVDRKTGQVRVEKLTIVTDAGTIVDPDGARAQTEGATLWGLSMALHEGTLFEKGQVRDTNLDTYTPLRIDETPELDI
SFVESTEMPVGLGEPATTVIAPAIGNAIFAAVGVRLRHLPITSEAVLSGLKTLG

Specific function: Presumed To Be A Dehydrogenase, But Possibly An Oxidase. Participates In Limited Purine Salvage (Requires Aspartate) But Does Not Support Aerobic Growth On Purines As The Sole Carbon Source (Purine Catabolism). Deletion Results In Increased Adenine Sensit

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=331, Percent_Identity=26.8882175226586, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1789230, Length=399, Percent_Identity=24.3107769423559, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786478, Length=504, Percent_Identity=27.5793650793651, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540638, Length=310, Percent_Identity=24.8387096774194, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737937, Length=315, Percent_Identity=26.031746031746, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.3 [H]

Molecular weight: Translated: 82568; Mature: 82437

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGSMQNAAMIQSRRSFLVTMAGASLAFGFTRGAGAAIDPATADGVPPNAVGTLFEPS
CCCCCCCCHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCC
LWYSIDSTGTVTVNIIRAEMGQHVGTALARILADELEADWKTVRITHVDTDPKWGLMVTG
EEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEC
GSWSVSQTWPIFSRAGAAGRLALIEAGAALLKVAPSACVARDGKVYAGTQSIAYGDIIAQ
CCCCCCCCCCHHHHCCCCCEEEEEHHCCHHHHCCCHHHHCCCCEEEECCCCEEECCCEEC
GPHFRQFSPEDLDKLTLKPVSERRLIGKPVTALDIPAKTNGEAVYGIDAKVPGMVHARPK
CCCCCCCCHHHHHHEECCCCHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCCEEECCCC
IPPTRYGSKVVSVDDSAARKVKGYLQSLVIDDPSETVPGWVLVIAESTFAAMRAADLVKV
CCCCCCCCEEEEECCHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCHHHHHHHCCEEEE
TWSAGPTAHISEKEIQDHAVEQIARRDNGVLLELGGAKGVDVAKPAFEAAASTLEQTYTT
EECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCE
ATVLHFQLEPLNALAFEKDGIFEIHTGNQWQSLILPVLAKALQRPQESIVLRSYMLGGGF
EEEEEEEECCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
GRRLNGDYAVPAALAAKALGRPVKVVLTRQDDALFDSVRSPSVQTVRMAFDAANKVTGME
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEHHHHHHHHHCCCCC
HHAAAGWPTEVMAPAFMPKGQEGKPFDPFAIAGADHWYDVGPQLVRALSNDLANATFRPG
CCCCCCCCHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHCCHHHHHHHHHHHCCCCCCCC
WLRSVGPGWINWALESFMDEAALHVKMDPLAFRLNLLNGKGQNDNAGSAPVSVGGASRQA
HHHCCCCHHHHHHHHHHHHHHEEEEEECCEEEEEEEECCCCCCCCCCCCCEECCCCCHHH
EVIRRAAQRAGWGQALPADTALGLATSFGQEREMPTWMACAARVHVDRKTGQVRVEKLTI
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHEEEECCCCCEEEEEEEE
VTDAGTIVDPDGARAQTEGATLWGLSMALHEGTLFEKGQVRDTNLDTYTPLRIDETPELD
EECCCCEECCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
ISFVESTEMPVGLGEPATTVIAPAIGNAIFAAVGVRLRHLPITSEAVLSGLKTLG
EEEEECCCCCCCCCCCCHHEEHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ARLGSMQNAAMIQSRRSFLVTMAGASLAFGFTRGAGAAIDPATADGVPPNAVGTLFEPS
CCCCCCCHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCC
LWYSIDSTGTVTVNIIRAEMGQHVGTALARILADELEADWKTVRITHVDTDPKWGLMVTG
EEEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEC
GSWSVSQTWPIFSRAGAAGRLALIEAGAALLKVAPSACVARDGKVYAGTQSIAYGDIIAQ
CCCCCCCCCCHHHHCCCCCEEEEEHHCCHHHHCCCHHHHCCCCEEEECCCCEEECCCEEC
GPHFRQFSPEDLDKLTLKPVSERRLIGKPVTALDIPAKTNGEAVYGIDAKVPGMVHARPK
CCCCCCCCHHHHHHEECCCCHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCCEEECCCC
IPPTRYGSKVVSVDDSAARKVKGYLQSLVIDDPSETVPGWVLVIAESTFAAMRAADLVKV
CCCCCCCCEEEEECCHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCHHHHHHHCCEEEE
TWSAGPTAHISEKEIQDHAVEQIARRDNGVLLELGGAKGVDVAKPAFEAAASTLEQTYTT
EECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCE
ATVLHFQLEPLNALAFEKDGIFEIHTGNQWQSLILPVLAKALQRPQESIVLRSYMLGGGF
EEEEEEEECCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
GRRLNGDYAVPAALAAKALGRPVKVVLTRQDDALFDSVRSPSVQTVRMAFDAANKVTGME
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEHHHHHHHHHCCCCC
HHAAAGWPTEVMAPAFMPKGQEGKPFDPFAIAGADHWYDVGPQLVRALSNDLANATFRPG
CCCCCCCCHHHCCCCCCCCCCCCCCCCCEEECCCCCHHHCCHHHHHHHHHHHCCCCCCCC
WLRSVGPGWINWALESFMDEAALHVKMDPLAFRLNLLNGKGQNDNAGSAPVSVGGASRQA
HHHCCCCHHHHHHHHHHHHHHEEEEEECCEEEEEEEECCCCCCCCCCCCCEECCCCCHHH
EVIRRAAQRAGWGQALPADTALGLATSFGQEREMPTWMACAARVHVDRKTGQVRVEKLTI
HHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHEEEECCCCCEEEEEEEE
VTDAGTIVDPDGARAQTEGATLWGLSMALHEGTLFEKGQVRDTNLDTYTPLRIDETPELD
EECCCCEECCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
ISFVESTEMPVGLGEPATTVIAPAIGNAIFAAVGVRLRHLPITSEAVLSGLKTLG
EEEEECCCCCCCCCCCCHHEEHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2606906 [H]