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The map label for this gene is pheA [H]

Identifier: 182680256

GI number: 182680256

Start: 3808279

End: 3809145

Strand: Reverse

Name: pheA [H]

Synonym: Bind_3356

Alternate gene names: 182680256

Gene position: 3809145-3808279 (Counterclockwise)

Preceding gene: 182680267

Following gene: 182680255

Centisome position: 91.34

GC content: 59.52

Gene sequence:

>867_bases
ATGCAGCCTCTCAAAATCGCCTATCAAGGCGAGCCCGGAGCCAATTCTCATATCGCTTGCCAGAGCGTCTATCCCGACTA
CGAGGCGCTGCCCTGCGCGACCTTCGAGGATGCGCTCGGCGCGATCAGCGATGGCACGGCGGCTTTGGGCATGATCCCGA
TTGAAAATTCGCTCGCCGGACGTGTCGCCGATATCCACCACCTGCTGCCGACCGCGGGGCTCTATATTGTCGGCGAATAT
TTTCTGCCGATTCATTTCCAGCTTTTGGGCCTCAAGGGGACAAAGATCGAGGATCTGCGATCAGTCTACAGCCATGTCCA
TGCGCTCGGCCAATGCCGCAAAATCATCCGGCGGCTGGGGCTAACCTCGCATGTCACGGGCGATACGGCAGGCTCGGCGC
GTGAAATCGCCGAATGGGGCGACAAGACCCGCGCCTCGCTCGCGCCACGACTCGCTGCTGAAATCTACGGGCTCGATATC
CTGGCCGAGAATGTCGAGGACGCGGCCCATAATACCACGCGTTTCGTCGTGCTCTCAAAGGAACCGGGATGGGCCCCGCT
CGGCACTCCCGATCCCATCACGAGTTTCGTGTTTCGGGTCCGCAACGTGCCGGCGGCGCTTTACAAGGCCCTCGGCGGTT
TCGCCACCAATGGCGTCAATATGACCAAGCTTGAAAGCTATATGGTGGAAGGTACATTTACCGCGACGCAATTTCTCGCT
GATGTCGATGGCCATCCACAAGAGCGGGGCCTTGCGCTGGCGCTGGAGGAACTGGCCTTTTTCTGCAAGGAATTGAAGAT
TCTCGGCGTCTATCCCGGTCATCCGTTCCGGCGCGAGAATCAGCCCTCGCCGGAGGGTATGTCATAG

Upstream 100 bases:

>100_bases
CGAAGAGCCTGATGAACGGGGCGGCTCGCCCGGCCGATGAACAAAGACGTGATTGAAACGGATCCCAGCGCCTGACGCCT
GGTCCGCAATGGAAAAACAG

Downstream 100 bases:

>100_bases
GGTGAGGATATGGACGAAGAAGAAATCATTTTGTTTCCGCTGATCGGTTTTTCCACCCATACTTTGCCGGGCTCCCTGGT
CATGCTAACGCTCGAATTGC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MQPLKIAYQGEPGANSHIACQSVYPDYEALPCATFEDALGAISDGTAALGMIPIENSLAGRVADIHHLLPTAGLYIVGEY
FLPIHFQLLGLKGTKIEDLRSVYSHVHALGQCRKIIRRLGLTSHVTGDTAGSAREIAEWGDKTRASLAPRLAAEIYGLDI
LAENVEDAAHNTTRFVVLSKEPGWAPLGTPDPITSFVFRVRNVPAALYKALGGFATNGVNMTKLESYMVEGTFTATQFLA
DVDGHPQERGLALALEELAFFCKELKILGVYPGHPFRRENQPSPEGMS

Sequences:

>Translated_288_residues
MQPLKIAYQGEPGANSHIACQSVYPDYEALPCATFEDALGAISDGTAALGMIPIENSLAGRVADIHHLLPTAGLYIVGEY
FLPIHFQLLGLKGTKIEDLRSVYSHVHALGQCRKIIRRLGLTSHVTGDTAGSAREIAEWGDKTRASLAPRLAAEIYGLDI
LAENVEDAAHNTTRFVVLSKEPGWAPLGTPDPITSFVFRVRNVPAALYKALGGFATNGVNMTKLESYMVEGTFTATQFLA
DVDGHPQERGLALALEELAFFCKELKILGVYPGHPFRRENQPSPEGMS
>Mature_288_residues
MQPLKIAYQGEPGANSHIACQSVYPDYEALPCATFEDALGAISDGTAALGMIPIENSLAGRVADIHHLLPTAGLYIVGEY
FLPIHFQLLGLKGTKIEDLRSVYSHVHALGQCRKIIRRLGLTSHVTGDTAGSAREIAEWGDKTRASLAPRLAAEIYGLDI
LAENVEDAAHNTTRFVVLSKEPGWAPLGTPDPITSFVFRVRNVPAALYKALGGFATNGVNMTKLESYMVEGTFTATQFLA
DVDGHPQERGLALALEELAFFCKELKILGVYPGHPFRRENQPSPEGMS

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=274, Percent_Identity=28.4671532846715, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31188; Mature: 31188

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLKIAYQGEPGANSHIACQSVYPDYEALPCATFEDALGAISDGTAALGMIPIENSLAG
CCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHH
RVADIHHLLPTAGLYIVGEYFLPIHFQLLGLKGTKIEDLRSVYSHVHALGQCRKIIRRLG
HHHHHHHHHHHCCCEEEEHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LTSHVTGDTAGSAREIAEWGDKTRASLAPRLAAEIYGLDILAENVEDAAHNTTRFVVLSK
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
EPGWAPLGTPDPITSFVFRVRNVPAALYKALGGFATNGVNMTKLESYMVEGTFTATQFLA
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHHCCCHHHHHHHH
DVDGHPQERGLALALEELAFFCKELKILGVYPGHPFRRENQPSPEGMS
HCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQPLKIAYQGEPGANSHIACQSVYPDYEALPCATFEDALGAISDGTAALGMIPIENSLAG
CCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHH
RVADIHHLLPTAGLYIVGEYFLPIHFQLLGLKGTKIEDLRSVYSHVHALGQCRKIIRRLG
HHHHHHHHHHHCCCEEEEHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LTSHVTGDTAGSAREIAEWGDKTRASLAPRLAAEIYGLDILAENVEDAAHNTTRFVVLSK
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
EPGWAPLGTPDPITSFVFRVRNVPAALYKALGGFATNGVNMTKLESYMVEGTFTATQFLA
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHHCCCHHHHHHHH
DVDGHPQERGLALALEELAFFCKELKILGVYPGHPFRRENQPSPEGMS
HCCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]