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The map label for this gene is appC [H]

Identifier: 182680190

GI number: 182680190

Start: 3741111

End: 3742499

Strand: Reverse

Name: appC [H]

Synonym: Bind_3288

Alternate gene names: 182680190

Gene position: 3742499-3741111 (Counterclockwise)

Preceding gene: 182680191

Following gene: 182680189

Centisome position: 89.74

GC content: 57.67

Gene sequence:

>1389_bases
ATGGCTTTCGACCCCGTCCTTTTGAGTCGTCTGCAATTTGCCTTCACCATTACTTTCCACATTATTTTTCCATCCTTCAC
GATTGGCCTTTCCGCCTTCATTGCGGTTTTGCTGGCGCGTCACGCGATCACTGGCCGTAGCCAGGATCTTGAACTGGCGC
GGTTCTGGACCAAGATCTTTGCCATTTCTTTCGCCATGGGCGTCGTTTCGGGCGTCGTCCTTTCCTATCAATTCGGCACC
AATTGGAGCCGTTTCTCCACCGTTGCCGGCAATATTATCGGCCCCTTGATGGCCTATGAGGTGCTGACCGCCTTCTTTCT
GGAGGCGACCTTTCTCGGCATCATGCTGTTCGGGGCGGGGCGCGTGCCGGGCTGGTTGCATCTGACCGCCTCGATCATGG
TGGCCATCGGCACAGCGATTTCCGCCTTCTGGATTCTCGCGGCCAATTCCTGGATGCAATTCCCGGTCGGCCATGAAATG
CGAGAGGGCATCGCCTTTCCCCTCGATTGGCTGCGGATCATCTTCAGTCCGACTTTTCCCTTGCGTTTCGCTCATATGGT
GACCGCGGCCTATATCACGACCGCCTTTGTCGTCGTGGCTGTCGGCGCCCGTTTTGCTCTCGCGGGCCGCTTTCCCGATC
ATGCGAAAACGATGCTGCGCATGGGACTTGGCCTCGCCGTGGTGCTGGTGCCCTTGCAGATTCTCATCGGTGATATGCAT
GGCCTCAAGACGGCGGAATATCAGCCGGCCAAGCTCGCGGCGATCGAGGGCCATTGGGAAAATGAAGAGGAAGGAGCGGG
CGTGCCCTTGATCCTCTTTGGTTGGCCGAACCAAAAGACTGAGACCAATGATTACGCGCTTTCCTTGCCGCATATCGGCA
GCCTGATCGTCACCCATTCCTGGGCCGGCCGTTTTCCCAGTCTGAAGGATTTCGCTCCGGCCGATCGTCCGCCGGTGCCA
CAAGTCTTCTTTGCCTTTCGTTTCATGGTCGGTATCGGTTTCGCCATGCTCGGATTTGTCGCCTGGGGGGTATTTTTGTG
GTGGCGTGGGGACCTGATGCGGAACAGGCTGTTCTTGCGCATCGCCGCCAATGTCTGGCCGGTTGGTTTTCTCGCCATCA
TCTCCGGTTGGATGGTGACGGAAATTGGTCGCCAGCCGTGGGTCGTGACCGGTTTTCTGCGTAGCGCCGATGCCGCTTCT
CCTTTGACGATGCACACGGTTCTGGTTTCGCTGGCGCTCTTCGTCCTTGTCTATGGTGTCGTGTTTTCGGCGGGGATCTA
TTTCATCAACCGGCTGATCAATGCGGGGCCGACACCTCATGTCGTTGGCGCCGAAACAGGCCTGCCGTCCCGTCCTCTGT
CCGGTGCTGCGAGAAGTCTGAGTGATTAA

Upstream 100 bases:

>100_bases
TCATCGTTCTTGTGCAAAATGAGCGAGGGGTTGGTTAGTGGCGGATGGTGCCGCGGCCAAGAATGGCAAGCAAACGAGAA
CATGAGAGAGGGAGCGTGTA

Downstream 100 bases:

>100_bases
ATCAACAACCGGCTGTTTCTGGGATGTTCGTTGGGAGAGAATGACATGACCGGCTTGGAACCGTATCTGCCGTTGATCTG
GGCCGGCATTCTGGCCACCG

Product: cytochrome bd ubiquinol oxidase subunit I

Products: NA

Alternate protein names: Cytochrome bd-II oxidase subunit I [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MAFDPVLLSRLQFAFTITFHIIFPSFTIGLSAFIAVLLARHAITGRSQDLELARFWTKIFAISFAMGVVSGVVLSYQFGT
NWSRFSTVAGNIIGPLMAYEVLTAFFLEATFLGIMLFGAGRVPGWLHLTASIMVAIGTAISAFWILAANSWMQFPVGHEM
REGIAFPLDWLRIIFSPTFPLRFAHMVTAAYITTAFVVVAVGARFALAGRFPDHAKTMLRMGLGLAVVLVPLQILIGDMH
GLKTAEYQPAKLAAIEGHWENEEEGAGVPLILFGWPNQKTETNDYALSLPHIGSLIVTHSWAGRFPSLKDFAPADRPPVP
QVFFAFRFMVGIGFAMLGFVAWGVFLWWRGDLMRNRLFLRIAANVWPVGFLAIISGWMVTEIGRQPWVVTGFLRSADAAS
PLTMHTVLVSLALFVLVYGVVFSAGIYFINRLINAGPTPHVVGAETGLPSRPLSGAARSLSD

Sequences:

>Translated_462_residues
MAFDPVLLSRLQFAFTITFHIIFPSFTIGLSAFIAVLLARHAITGRSQDLELARFWTKIFAISFAMGVVSGVVLSYQFGT
NWSRFSTVAGNIIGPLMAYEVLTAFFLEATFLGIMLFGAGRVPGWLHLTASIMVAIGTAISAFWILAANSWMQFPVGHEM
REGIAFPLDWLRIIFSPTFPLRFAHMVTAAYITTAFVVVAVGARFALAGRFPDHAKTMLRMGLGLAVVLVPLQILIGDMH
GLKTAEYQPAKLAAIEGHWENEEEGAGVPLILFGWPNQKTETNDYALSLPHIGSLIVTHSWAGRFPSLKDFAPADRPPVP
QVFFAFRFMVGIGFAMLGFVAWGVFLWWRGDLMRNRLFLRIAANVWPVGFLAIISGWMVTEIGRQPWVVTGFLRSADAAS
PLTMHTVLVSLALFVLVYGVVFSAGIYFINRLINAGPTPHVVGAETGLPSRPLSGAARSLSD
>Mature_461_residues
AFDPVLLSRLQFAFTITFHIIFPSFTIGLSAFIAVLLARHAITGRSQDLELARFWTKIFAISFAMGVVSGVVLSYQFGTN
WSRFSTVAGNIIGPLMAYEVLTAFFLEATFLGIMLFGAGRVPGWLHLTASIMVAIGTAISAFWILAANSWMQFPVGHEMR
EGIAFPLDWLRIIFSPTFPLRFAHMVTAAYITTAFVVVAVGARFALAGRFPDHAKTMLRMGLGLAVVLVPLQILIGDMHG
LKTAEYQPAKLAAIEGHWENEEEGAGVPLILFGWPNQKTETNDYALSLPHIGSLIVTHSWAGRFPSLKDFAPADRPPVPQ
VFFAFRFMVGIGFAMLGFVAWGVFLWWRGDLMRNRLFLRIAANVWPVGFLAIISGWMVTEIGRQPWVVTGFLRSADAASP
LTMHTVLVSLALFVLVYGVVFSAGIYFINRLINAGPTPHVVGAETGLPSRPLSGAARSLSD

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=509, Percent_Identity=31.237721021611, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87081779, Length=511, Percent_Identity=30.9197651663405, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.-

Molecular weight: Translated: 50656; Mature: 50525

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDPVLLSRLQFAFTITFHIIFPSFTIGLSAFIAVLLARHAITGRSQDLELARFWTKIF
CCCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AISFAMGVVSGVVLSYQFGTNWSRFSTVAGNIIGPLMAYEVLTAFFLEATFLGIMLFGAG
HHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RVPGWLHLTASIMVAIGTAISAFWILAANSWMQFPVGHEMREGIAFPLDWLRIIFSPTFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCH
LRFAHMVTAAYITTAFVVVAVGARFALAGRFPDHAKTMLRMGLGLAVVLVPLQILIGDMH
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLKTAEYQPAKLAAIEGHWENEEEGAGVPLILFGWPNQKTETNDYALSLPHIGSLIVTHS
CCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEEEC
WAGRFPSLKDFAPADRPPVPQVFFAFRFMVGIGFAMLGFVAWGVFLWWRGDLMRNRLFLR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IAANVWPVGFLAIISGWMVTEIGRQPWVVTGFLRSADAASPLTMHTVLVSLALFVLVYGV
ECCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VFSAGIYFINRLINAGPTPHVVGAETGLPSRPLSGAARSLSD
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
AFDPVLLSRLQFAFTITFHIIFPSFTIGLSAFIAVLLARHAITGRSQDLELARFWTKIF
CCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AISFAMGVVSGVVLSYQFGTNWSRFSTVAGNIIGPLMAYEVLTAFFLEATFLGIMLFGAG
HHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RVPGWLHLTASIMVAIGTAISAFWILAANSWMQFPVGHEMREGIAFPLDWLRIIFSPTFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCH
LRFAHMVTAAYITTAFVVVAVGARFALAGRFPDHAKTMLRMGLGLAVVLVPLQILIGDMH
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLKTAEYQPAKLAAIEGHWENEEEGAGVPLILFGWPNQKTETNDYALSLPHIGSLIVTHS
CCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEEEC
WAGRFPSLKDFAPADRPPVPQVFFAFRFMVGIGFAMLGFVAWGVFLWWRGDLMRNRLFLR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IAANVWPVGFLAIISGWMVTEIGRQPWVVTGFLRSADAASPLTMHTVLVSLALFVLVYGV
ECCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VFSAGIYFINRLINAGPTPHVVGAETGLPSRPLSGAARSLSD
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]