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The map label for this gene is mog [H]

Identifier: 182680185

GI number: 182680185

Start: 3735422

End: 3735967

Strand: Reverse

Name: mog [H]

Synonym: Bind_3282

Alternate gene names: 182680185

Gene position: 3735967-3735422 (Counterclockwise)

Preceding gene: 182680186

Following gene: 182680184

Centisome position: 89.59

GC content: 61.72

Gene sequence:

>546_bases
ATGACCGAAGAAGCAAAACACAGCGCGATCATCGGCGTCGTCACCGTTTCCGATCGGGCTTCGCAAGGGCTTTACGAAGA
CCGTAGCGGGCCAGCTATTCTTGCCTTTCTGCAACGGGTGCTGACGACACCCTTTGCCGCTCTGCACAAAATCATCCCCG
ATGGATTCGAGAGCGTGCGCGACACATTGATCACCCTCGCCGACGAGGACCGTTGCGATCTCATCCTCACGACCGGAGGC
ACCGGACCCGCCCCACGCGACCTGACGCCGGAGGCGACCGAGGCGGCGGCCCCGCGCATCCTGCCGGGCTTTGGCGAATT
GATGCGCAAGGTCAGCCTGGAGGAAGTTCCCACGGCCATTCTCTCGCGGCAGATCGCCGCCCATCGTGGTTCCTGTCTCA
TCATCAATCTACCGGGCAAGCCCGCGGCCATCGAGACCTGTCTCAAGGCGGTCTTCCCAGCCGTGCCTTATTGCCTCGAT
CTCATCGGTGCGGCCCGGATCGAGACCAATCCTGCGGAGATCAAAGCATTTCGCCCCAAAGCATGA

Upstream 100 bases:

>100_bases
ACTAAATGCCGCTGGATGGTTCAAAAAAGCGCTCCGATCCTTTAGGTTGGGCCTCGGGTTCGGGCTGTTGCAGCGGTCTC
GAAGACGGAAGGGTTCAAGG

Downstream 100 bases:

>100_bases
TGCAGTAAAAACAGAATGGCATCATGCTTGAGAATAGTGAGAATGCGCTGAATCCAAATGTGGTATCCACATTTGGATTC
AGCGTTATAGGGCCTGAAAG

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTEEAKHSAIIGVVTVSDRASQGLYEDRSGPAILAFLQRVLTTPFAALHKIIPDGFESVRDTLITLADEDRCDLILTTGG
TGPAPRDLTPEATEAAAPRILPGFGELMRKVSLEEVPTAILSRQIAAHRGSCLIINLPGKPAAIETCLKAVFPAVPYCLD
LIGAARIETNPAEIKAFRPKA

Sequences:

>Translated_181_residues
MTEEAKHSAIIGVVTVSDRASQGLYEDRSGPAILAFLQRVLTTPFAALHKIIPDGFESVRDTLITLADEDRCDLILTTGG
TGPAPRDLTPEATEAAAPRILPGFGELMRKVSLEEVPTAILSRQIAAHRGSCLIINLPGKPAAIETCLKAVFPAVPYCLD
LIGAARIETNPAEIKAFRPKA
>Mature_180_residues
TEEAKHSAIIGVVTVSDRASQGLYEDRSGPAILAFLQRVLTTPFAALHKIIPDGFESVRDTLITLADEDRCDLILTTGGT
GPAPRDLTPEATEAAAPRILPGFGELMRKVSLEEVPTAILSRQIAAHRGSCLIINLPGKPAAIETCLKAVFPAVPYCLDL
IGAARIETNPAEIKAFRPKA

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=158, Percent_Identity=43.6708860759494, Blast_Score=124, Evalue=6e-29,
Organism=Homo sapiens, GI10880983, Length=158, Percent_Identity=43.6708860759494, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI1786190, Length=183, Percent_Identity=49.1803278688525, Blast_Score=174, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17564954, Length=158, Percent_Identity=34.8101265822785, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136978, Length=160, Percent_Identity=34.375, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24638841, Length=160, Percent_Identity=34.375, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19296; Mature: 19164

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEAKHSAIIGVVTVSDRASQGLYEDRSGPAILAFLQRVLTTPFAALHKIIPDGFESVR
CCCCCCCCEEEEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHH
DTLITLADEDRCDLILTTGGTGPAPRDLTPEATEAAAPRILPGFGELMRKVSLEEVPTAI
HHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LSRQIAAHRGSCLIINLPGKPAAIETCLKAVFPAVPYCLDLIGAARIETNPAEIKAFRPK
HHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCC
A
C
>Mature Secondary Structure 
TEEAKHSAIIGVVTVSDRASQGLYEDRSGPAILAFLQRVLTTPFAALHKIIPDGFESVR
CCCCCCCEEEEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHH
DTLITLADEDRCDLILTTGGTGPAPRDLTPEATEAAAPRILPGFGELMRKVSLEEVPTAI
HHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LSRQIAAHRGSCLIINLPGKPAAIETCLKAVFPAVPYCLDLIGAARIETNPAEIKAFRPK
HHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]