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The map label for this gene is efp1 [H]

Identifier: 182680120

GI number: 182680120

Start: 3661560

End: 3662126

Strand: Reverse

Name: efp1 [H]

Synonym: Bind_3217

Alternate gene names: 182680120

Gene position: 3662126-3661560 (Counterclockwise)

Preceding gene: 182680121

Following gene: 182680119

Centisome position: 87.82

GC content: 56.44

Gene sequence:

>567_bases
ATGCCCAAGATCAACGGAAACCAGATCACGCCCGGAACCGTCATCGAGCATGACGGTGGTCTCTGGGCTGCCGTCAAATC
CACGACAGTCAAGCCCGGTAAGGGCGGCGCGTTCAATCAGGTCGAACTGAAAAACCTCATCGATGGCCGCAAATTGAACG
AGCGATTCCGGGCCGATGCCACGGTTGATGAAGTCGAACTTGAATTGAAGGATTTCAGCTTTCTCTATGCGCAAGGGGAA
GAATTGGTCTTCATGGATCTCGAAAGCTATGAGCAGATCGAACTCGCCGCCGATTGGGTCGGCGAGCGCGCGGCTTTTCT
GCAGGACGGGATGAAGGTGACCTTGCGCATGCATGAGGCGCGGCCGATCAGCATCAAATTGCCGGCCTATGTGACGCTGG
AAATTGCTGAGGCCGATCCGGTGGTACGGGGCCAGACGGCGACCTCGACCTACAAACCGGCAATCCTCGAAAATGGTTTG
CGCGTCCTGGTGCCGCCCTTTATCGAAAAAGGCGAGCGCATTGTCGTGGATACAAATGAGGTCACATACATGCGGCGCGC
GGACTAG

Upstream 100 bases:

>100_bases
GGGCACATGAAGGATCGAAATGCTCGTGCGACTGGTCGTCAGGAACGATCGTCCGCACGTTTTCCGATATTAGCGCCGCT
TCTCACCCGCACGAGACCCC

Downstream 100 bases:

>100_bases
TGCGCTGACACATTCAACAGAGAGCTTTCAAGATCTCTGTATGTGATCTCTTGAATTCAGGCTGAGTCTCGCCTGCGCTG
CGAAGAAGCATCGCTCTGGG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 1 [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MPKINGNQITPGTVIEHDGGLWAAVKSTTVKPGKGGAFNQVELKNLIDGRKLNERFRADATVDEVELELKDFSFLYAQGE
ELVFMDLESYEQIELAADWVGERAAFLQDGMKVTLRMHEARPISIKLPAYVTLEIAEADPVVRGQTATSTYKPAILENGL
RVLVPPFIEKGERIVVDTNEVTYMRRAD

Sequences:

>Translated_188_residues
MPKINGNQITPGTVIEHDGGLWAAVKSTTVKPGKGGAFNQVELKNLIDGRKLNERFRADATVDEVELELKDFSFLYAQGE
ELVFMDLESYEQIELAADWVGERAAFLQDGMKVTLRMHEARPISIKLPAYVTLEIAEADPVVRGQTATSTYKPAILENGL
RVLVPPFIEKGERIVVDTNEVTYMRRAD
>Mature_187_residues
PKINGNQITPGTVIEHDGGLWAAVKSTTVKPGKGGAFNQVELKNLIDGRKLNERFRADATVDEVELELKDFSFLYAQGEE
LVFMDLESYEQIELAADWVGERAAFLQDGMKVTLRMHEARPISIKLPAYVTLEIAEADPVVRGQTATSTYKPAILENGLR
VLVPPFIEKGERIVVDTNEVTYMRRAD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=186, Percent_Identity=34.9462365591398, Blast_Score=114, Evalue=3e-27,
Organism=Escherichia coli, GI87082061, Length=192, Percent_Identity=32.2916666666667, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20965; Mature: 20834

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKINGNQITPGTVIEHDGGLWAAVKSTTVKPGKGGAFNQVELKNLIDGRKLNERFRADA
CCCCCCCEECCCEEEEECCCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCHHHHHHCCCC
TVDEVELELKDFSFLYAQGEELVFMDLESYEQIELAADWVGERAAFLQDGMKVTLRMHEA
CHHHEEEEEECEEEEEECCCEEEEEECCCCCEEEHHHHHHCHHHHHHHCCEEEEEEEECC
RPISIKLPAYVTLEIAEADPVVRGQTATSTYKPAILENGLRVLVPPFIEKGERIVVDTNE
CCEEEECCEEEEEEEECCCCEECCCCCCCCCCCHHHHCCCEEEECHHHCCCCEEEEECCC
VTYMRRAD
EEEEEECC
>Mature Secondary Structure 
PKINGNQITPGTVIEHDGGLWAAVKSTTVKPGKGGAFNQVELKNLIDGRKLNERFRADA
CCCCCCEECCCEEEEECCCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCHHHHHHCCCC
TVDEVELELKDFSFLYAQGEELVFMDLESYEQIELAADWVGERAAFLQDGMKVTLRMHEA
CHHHEEEEEECEEEEEECCCEEEEEECCCCCEEEHHHHHHCHHHHHHHCCEEEEEEEECC
RPISIKLPAYVTLEIAEADPVVRGQTATSTYKPAILENGLRVLVPPFIEKGERIVVDTNE
CCEEEECCEEEEEEEECCCCEECCCCCCCCCCCHHHHCCCEEEECHHHCCCCEEEEECCC
VTYMRRAD
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]