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The map label for this gene is 182680105

Identifier: 182680105

GI number: 182680105

Start: 3644206

End: 3645774

Strand: Reverse

Name: 182680105

Synonym: Bind_3202

Alternate gene names: NA

Gene position: 3645774-3644206 (Counterclockwise)

Preceding gene: 182680106

Following gene: 182680103

Centisome position: 87.43

GC content: 55.64

Gene sequence:

>1569_bases
ATGACTAAATTCGATCTCAATGATGATTCTGTTGTCGTGATCATCGGTTCCGGCGCGGGTGGGGGAACGCTCGGCACGGA
GCTCGCCTTGAAAGGTATCAAGGTTGTGATGCTCGAGGCTGGACCCCGTTTCGAAATCGAGGATTTCATCAACGACGAAT
GGGAGAGCTTCACGCAATTGTCCTGGAGCGATATGCGTACGACGTCAGGCTCCTGGCGCGTTCATAAGGACTTCCCGAAT
CTGCCGGCCTGGATCGTCAAAGCGGTTGGTGGCACCTCCATCCATTGGGCGGGGGCCTCGCTGCGGTTCCAGGACCATGA
ATTCAAGACCCGCACGCATTACGGAGAGGTCCAGGGCGCAAACCTCCTCGATTGGCCGATTACACTCAAGGATCTCGAGC
CCTATTATGACAAGGCCGAGTCCAAAATGGGTGTCACACGGACCAATGGGATCCCCGGCCTACCAGGCAATAATAATTAC
AAGATCCTGGAAGCCGGTGCGAAGGCCCTCGGCTATAAGGAGGTTCATACGGGACGCATGGCGATCAATTCGCAGCCGCG
TGACGGCCGTGGCAGTTGCCAGCAGATCGGTTTCTGTTTCCAAGGCTGTAAATCCGGCGCGAAATGGTCGACGCTTTACG
CCGAAATCCCGAAAGGCGAGGAAACCGGCAAGCTTGAGGTTCGGCCGGAAAGCCACGTTCTGCGCATCGAACACGATGCC
AATGGCAAAGTCACCGGTGTCGTTTACGCCGATAGTCAGGGCAATCGGCAAAGACAGAAGGCGCGTATCGTCTGCATTGC
CGGCAATTCGATCGAAAGTCCGCGTATTCTGCTCAATTCGGCCTCAAATCTGTTCCCGGATGGTCTCGCCAATTCCTCGG
GTCAGGTCGGACGCAATTACATGCGGCATACGACCGGTGCTGTCTTCGGAATTTTCGATCGGCCGATCCATATGTATCGT
GGCACGACCATGGCCGGTATCGTCCGCGATGAAAGTGGTCACAAACCGGAACGCGGTTTCGTCGGTGGCTATGAACTGGA
GACGATTTCGGTCGGCCTGCCCTTCATGGCGGCCTTCCTCAACCCTGGTTCCTGGGGCAGGAGTATCACGTCGGCGCTCG
ATTCCTATCAGAATATGGCAGGTCTCTGGATCGTCGGTGAGGATATGCCGCAGGAGACGAATCGCGTCACTTTGGACAAT
GCGGCCAAGGACAAATATGGTCTGCCGGTCGCTAATGTTCATTATGATGATCACGCCAATGACATTGCCATGCGCAATCA
TGCCTATGAGCGCTCGACTGCGCTTTATGAGGCCGTAGGCGCCAGGCGCGTCTTCCCGCAGACACCTTATCCATCGACGC
ATAATCTCGGCACCAATCGCATGTCCGAAAAGCCTCGTGATGGCGTCGTGAACAAATATGGCCAGACCCATGACATCAAG
AATCTCTTTGTGTCGGATGGGTCACAATTCACGACGGGGGCCGGCGAAAATCCGACGCTGACCATTGTCGCGCTTGCTAT
CCGGCAAGCTGACTACATTGCTGCGGAAATGGGCAAGCGTACAATCTGA

Upstream 100 bases:

>100_bases
TCGGTTATGAAGGCGAGAGCGCCTCGAAGGGCGGCTATATTAATCGCGGCTTCAACGATCTGGCTTGGCTCTAGGCGGCG
GCATCAGGGAGGGCGCATTC

Downstream 100 bases:

>100_bases
CCAATTCCGTTCGAAGGAGAAGATGATGTTCTCCTTCGAATCCTCGCTGAGGGTGAGCACTTCGAGACGGCATCGCCGAT
ACATTTTCAAGTGATGCAAT

Product: gluconate 2-dehydrogenase (acceptor)

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MTKFDLNDDSVVVIIGSGAGGGTLGTELALKGIKVVMLEAGPRFEIEDFINDEWESFTQLSWSDMRTTSGSWRVHKDFPN
LPAWIVKAVGGTSIHWAGASLRFQDHEFKTRTHYGEVQGANLLDWPITLKDLEPYYDKAESKMGVTRTNGIPGLPGNNNY
KILEAGAKALGYKEVHTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYAEIPKGEETGKLEVRPESHVLRIEHDA
NGKVTGVVYADSQGNRQRQKARIVCIAGNSIESPRILLNSASNLFPDGLANSSGQVGRNYMRHTTGAVFGIFDRPIHMYR
GTTMAGIVRDESGHKPERGFVGGYELETISVGLPFMAAFLNPGSWGRSITSALDSYQNMAGLWIVGEDMPQETNRVTLDN
AAKDKYGLPVANVHYDDHANDIAMRNHAYERSTALYEAVGARRVFPQTPYPSTHNLGTNRMSEKPRDGVVNKYGQTHDIK
NLFVSDGSQFTTGAGENPTLTIVALAIRQADYIAAEMGKRTI

Sequences:

>Translated_522_residues
MTKFDLNDDSVVVIIGSGAGGGTLGTELALKGIKVVMLEAGPRFEIEDFINDEWESFTQLSWSDMRTTSGSWRVHKDFPN
LPAWIVKAVGGTSIHWAGASLRFQDHEFKTRTHYGEVQGANLLDWPITLKDLEPYYDKAESKMGVTRTNGIPGLPGNNNY
KILEAGAKALGYKEVHTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYAEIPKGEETGKLEVRPESHVLRIEHDA
NGKVTGVVYADSQGNRQRQKARIVCIAGNSIESPRILLNSASNLFPDGLANSSGQVGRNYMRHTTGAVFGIFDRPIHMYR
GTTMAGIVRDESGHKPERGFVGGYELETISVGLPFMAAFLNPGSWGRSITSALDSYQNMAGLWIVGEDMPQETNRVTLDN
AAKDKYGLPVANVHYDDHANDIAMRNHAYERSTALYEAVGARRVFPQTPYPSTHNLGTNRMSEKPRDGVVNKYGQTHDIK
NLFVSDGSQFTTGAGENPTLTIVALAIRQADYIAAEMGKRTI
>Mature_521_residues
TKFDLNDDSVVVIIGSGAGGGTLGTELALKGIKVVMLEAGPRFEIEDFINDEWESFTQLSWSDMRTTSGSWRVHKDFPNL
PAWIVKAVGGTSIHWAGASLRFQDHEFKTRTHYGEVQGANLLDWPITLKDLEPYYDKAESKMGVTRTNGIPGLPGNNNYK
ILEAGAKALGYKEVHTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYAEIPKGEETGKLEVRPESHVLRIEHDAN
GKVTGVVYADSQGNRQRQKARIVCIAGNSIESPRILLNSASNLFPDGLANSSGQVGRNYMRHTTGAVFGIFDRPIHMYRG
TTMAGIVRDESGHKPERGFVGGYELETISVGLPFMAAFLNPGSWGRSITSALDSYQNMAGLWIVGEDMPQETNRVTLDNA
AKDKYGLPVANVHYDDHANDIAMRNHAYERSTALYEAVGARRVFPQTPYPSTHNLGTNRMSEKPRDGVVNKYGQTHDIKN
LFVSDGSQFTTGAGENPTLTIVALAIRQADYIAAEMGKRTI

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 57299; Mature: 57168

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFDLNDDSVVVIIGSGAGGGTLGTELALKGIKVVMLEAGPRFEIEDFINDEWESFTQL
CCEECCCCCCEEEEEECCCCCCCHHHHHHHCCEEEEEECCCCCEEHHHHHCHHHHHHHHC
SWSDMRTTSGSWRVHKDFPNLPAWIVKAVGGTSIHWAGASLRFQDHEFKTRTHYGEVQGA
CHHHHCCCCCCEEEECCCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCCCCC
NLLDWPITLKDLEPYYDKAESKMGVTRTNGIPGLPGNNNYKILEAGAKALGYKEVHTGRM
EEEECCEEHCCCCHHHHHHHHCCCCEECCCCCCCCCCCCEEEEECCHHHCCCHHHCCCEE
AINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYAEIPKGEETGKLEVRPESHVLRIEHDA
EECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCCCEEEEEECC
NGKVTGVVYADSQGNRQRQKARIVCIAGNSIESPRILLNSASNLFPDGLANSSGQVGRNY
CCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
MRHTTGAVFGIFDRPIHMYRGTTMAGIVRDESGHKPERGFVGGYELETISVGLPFMAAFL
HHHHCCCEEEEECCCEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECHHHHHHHC
NPGSWGRSITSALDSYQNMAGLWIVGEDMPQETNRVTLDNAAKDKYGLPVANVHYDDHAN
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCC
DIAMRNHAYERSTALYEAVGARRVFPQTPYPSTHNLGTNRMSEKPRDGVVNKYGQTHDIK
CHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHH
NLFVSDGSQFTTGAGENPTLTIVALAIRQADYIAAEMGKRTI
HHEECCCCEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKFDLNDDSVVVIIGSGAGGGTLGTELALKGIKVVMLEAGPRFEIEDFINDEWESFTQL
CEECCCCCCEEEEEECCCCCCCHHHHHHHCCEEEEEECCCCCEEHHHHHCHHHHHHHHC
SWSDMRTTSGSWRVHKDFPNLPAWIVKAVGGTSIHWAGASLRFQDHEFKTRTHYGEVQGA
CHHHHCCCCCCEEEECCCCCCHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCCCCC
NLLDWPITLKDLEPYYDKAESKMGVTRTNGIPGLPGNNNYKILEAGAKALGYKEVHTGRM
EEEECCEEHCCCCHHHHHHHHCCCCEECCCCCCCCCCCCEEEEECCHHHCCCHHHCCCEE
AINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYAEIPKGEETGKLEVRPESHVLRIEHDA
EECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCCCEEEEEECC
NGKVTGVVYADSQGNRQRQKARIVCIAGNSIESPRILLNSASNLFPDGLANSSGQVGRNY
CCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
MRHTTGAVFGIFDRPIHMYRGTTMAGIVRDESGHKPERGFVGGYELETISVGLPFMAAFL
HHHHCCCEEEEECCCEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECHHHHHHHC
NPGSWGRSITSALDSYQNMAGLWIVGEDMPQETNRVTLDNAAKDKYGLPVANVHYDDHAN
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCC
DIAMRNHAYERSTALYEAVGARRVFPQTPYPSTHNLGTNRMSEKPRDGVVNKYGQTHDIK
CHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHH
NLFVSDGSQFTTGAGENPTLTIVALAIRQADYIAAEMGKRTI
HHEECCCCEEECCCCCCCCEEEEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]