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The map label for this gene is alr [H]

Identifier: 182680013

GI number: 182680013

Start: 3555785

End: 3556906

Strand: Reverse

Name: alr [H]

Synonym: Bind_3109

Alternate gene names: 182680013

Gene position: 3556906-3555785 (Counterclockwise)

Preceding gene: 182680014

Following gene: 182680012

Centisome position: 85.29

GC content: 59.71

Gene sequence:

>1122_bases
ATGGACCAGAAAGAGATCAGCCTGCGGGGCGCGGGCGCTATTCTGACCATCGATCTTGCCGCCATCGTCGCCAATTGGCA
GACGCTCCAGGCGGTATCCGGCACGGAATGCGGAGCGGTCGTCAAGGCTGATGCCTATGGTCTCGGCCTTCATCCCGTAG
TCAAGGCCCTCTACGAGGCCGGCTGCAGGACTTTTTTCGTTGCCCATGCCTTTGAGGGCGCCGAGGTGCGGGCGCTTGCT
CCGGAGGCCATTATCTATGTCCTGAATGGTGTCAGGCCGGCGCAGGAATATACATTCGCCGCGCATAATTTGCGTCCCGT
TCTCAATTCCGTGCCGGAAGTTGAGGACTGGGGACAATATTGCGCGACGTCGCATAAAAGAGCGCCTGATGGTTCCCTTT
TGAAGGCGGGATTGCGGATCGATACGGGTGTCAACCAGCTCGGTCTGAAGCTCTATGATCTTGAGCGCGTCGATCATCTT
TCGCCCCTGTTCGACGTCACCTTGCTCTTGAGCCAGCTCGTGACCGCCGACGACAGTATCGCGGACCGCCAGATCGAGGC
GTTCGACAAGATCCGTGCGCGCTATCCGGGTGTGCCCGCATCGCTCGCCAATTCGGCGGCGATCTTTCTCGACAATAATC
CACCGCTCTATGATCTCGTGCGGCCGGGCTATGCGCTTTATGGCGGTAACCCGGTGCCGGGCCGCCCCAATCCCATGCGA
CCTGTCGTTCGGCTCGATGCGCATATCATCCAGGTCCGGGTGCTGGAGCCCGGCCATAGCGTCGGCGTAGAGCGCCTATG
GAAGGCGCGGGGGCCGCGCCGTGTCATCATGGTGGCAGCGGGACTTGCGGACGGCATTCCCTCCGGGCTCACCGATAATG
AAAAACATGTCGGTGGCAAGGCTCTGATCCAGGGCACGCTCTGCCCTTATGTGAGCGACATTGCCATGGATTACAGCGTG
ATCGACGTCTCCGATGCGACTTATCTCGAACGTGGTGAAATGGTCGAATTACTGGGCAAGACGGTCACGATCGACGATTT
CGCGGCCATGGCGAATGTCAGCGGCTATGAAATCCTGAGCAATCTCGGCCGTCGCTGTCACCGCCGCTATCAGCCCTTGT
AA

Upstream 100 bases:

>100_bases
GCTGACTCCGTGCCATTGCCCAGCTGCACGGAATTTGCGTAAAAGAACAGCCTCGCGCGAGCGGGCCCTTTTACAGCCAT
ATTACGGATTTCCCGACTTC

Downstream 100 bases:

>100_bases
CTTTGCTTTTGTAACCTTGCCTTCGCAAACGCTCAATCGATCCGATAAAGAGCAGCGTGTTCGCCTGGTCACGGCTATTT
TACTTGGAGAAAATGCTGTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MDQKEISLRGAGAILTIDLAAIVANWQTLQAVSGTECGAVVKADAYGLGLHPVVKALYEAGCRTFFVAHAFEGAEVRALA
PEAIIYVLNGVRPAQEYTFAAHNLRPVLNSVPEVEDWGQYCATSHKRAPDGSLLKAGLRIDTGVNQLGLKLYDLERVDHL
SPLFDVTLLLSQLVTADDSIADRQIEAFDKIRARYPGVPASLANSAAIFLDNNPPLYDLVRPGYALYGGNPVPGRPNPMR
PVVRLDAHIIQVRVLEPGHSVGVERLWKARGPRRVIMVAAGLADGIPSGLTDNEKHVGGKALIQGTLCPYVSDIAMDYSV
IDVSDATYLERGEMVELLGKTVTIDDFAAMANVSGYEILSNLGRRCHRRYQPL

Sequences:

>Translated_373_residues
MDQKEISLRGAGAILTIDLAAIVANWQTLQAVSGTECGAVVKADAYGLGLHPVVKALYEAGCRTFFVAHAFEGAEVRALA
PEAIIYVLNGVRPAQEYTFAAHNLRPVLNSVPEVEDWGQYCATSHKRAPDGSLLKAGLRIDTGVNQLGLKLYDLERVDHL
SPLFDVTLLLSQLVTADDSIADRQIEAFDKIRARYPGVPASLANSAAIFLDNNPPLYDLVRPGYALYGGNPVPGRPNPMR
PVVRLDAHIIQVRVLEPGHSVGVERLWKARGPRRVIMVAAGLADGIPSGLTDNEKHVGGKALIQGTLCPYVSDIAMDYSV
IDVSDATYLERGEMVELLGKTVTIDDFAAMANVSGYEILSNLGRRCHRRYQPL
>Mature_373_residues
MDQKEISLRGAGAILTIDLAAIVANWQTLQAVSGTECGAVVKADAYGLGLHPVVKALYEAGCRTFFVAHAFEGAEVRALA
PEAIIYVLNGVRPAQEYTFAAHNLRPVLNSVPEVEDWGQYCATSHKRAPDGSLLKAGLRIDTGVNQLGLKLYDLERVDHL
SPLFDVTLLLSQLVTADDSIADRQIEAFDKIRARYPGVPASLANSAAIFLDNNPPLYDLVRPGYALYGGNPVPGRPNPMR
PVVRLDAHIIQVRVLEPGHSVGVERLWKARGPRRVIMVAAGLADGIPSGLTDNEKHVGGKALIQGTLCPYVSDIAMDYSV
IDVSDATYLERGEMVELLGKTVTIDDFAAMANVSGYEILSNLGRRCHRRYQPL

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=30.0546448087432, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=26.4150943396226, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40433; Mature: 40433

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQKEISLRGAGAILTIDLAAIVANWQTLQAVSGTECGAVVKADAYGLGLHPVVKALYEA
CCCCCEEEECCCEEEEEEHHHHHHCHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHC
GCRTFFVAHAFEGAEVRALAPEAIIYVLNGVRPAQEYTFAAHNLRPVLNSVPEVEDWGQY
CCCEEEEEECCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
CATSHKRAPDGSLLKAGLRIDTGVNQLGLKLYDLERVDHLSPLFDVTLLLSQLVTADDSI
HHCCCCCCCCCHHHHCCCEECCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHH
ADRQIEAFDKIRARYPGVPASLANSAAIFLDNNPPLYDLVRPGYALYGGNPVPGRPNPMR
HHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCHHHHCCCEEEECCCCCCCCCCCCC
PVVRLDAHIIQVRVLEPGHSVGVERLWKARGPRRVIMVAAGLADGIPSGLTDNEKHVGGK
HHHHCCEEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEEECHHCCCCCCCCCCCHHCCCH
ALIQGTLCPYVSDIAMDYSVIDVSDATYLERGEMVELLGKTVTIDDFAAMANVSGYEILS
HEEECCHHHHHHHHHCCEEEEECCCCHHHHCCHHHHHHCCEEEEHHHHHHHCCCHHHHHH
NLGRRCHRRYQPL
HHHHHHHHHCCCC
>Mature Secondary Structure
MDQKEISLRGAGAILTIDLAAIVANWQTLQAVSGTECGAVVKADAYGLGLHPVVKALYEA
CCCCCEEEECCCEEEEEEHHHHHHCHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHC
GCRTFFVAHAFEGAEVRALAPEAIIYVLNGVRPAQEYTFAAHNLRPVLNSVPEVEDWGQY
CCCEEEEEECCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
CATSHKRAPDGSLLKAGLRIDTGVNQLGLKLYDLERVDHLSPLFDVTLLLSQLVTADDSI
HHCCCCCCCCCHHHHCCCEECCCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHH
ADRQIEAFDKIRARYPGVPASLANSAAIFLDNNPPLYDLVRPGYALYGGNPVPGRPNPMR
HHHHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCHHHHCCCEEEECCCCCCCCCCCCC
PVVRLDAHIIQVRVLEPGHSVGVERLWKARGPRRVIMVAAGLADGIPSGLTDNEKHVGGK
HHHHCCEEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEEECHHCCCCCCCCCCCHHCCCH
ALIQGTLCPYVSDIAMDYSVIDVSDATYLERGEMVELLGKTVTIDDFAAMANVSGYEILS
HEEECCHHHHHHHHHCCEEEEECCCCHHHHCCHHHHHHCCEEEEHHHHHHHCCCHHHHHH
NLGRRCHRRYQPL
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA