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The map label for this gene is fabH [H]

Identifier: 182679922

GI number: 182679922

Start: 3436872

End: 3437918

Strand: Reverse

Name: fabH [H]

Synonym: Bind_3017

Alternate gene names: 182679922

Gene position: 3437918-3436872 (Counterclockwise)

Preceding gene: 182679923

Following gene: 182679921

Centisome position: 82.44

GC content: 57.59

Gene sequence:

>1047_bases
GTGGGCACAATAATATTCCTCCTGACGACCGGACCGCATGACCGGCCGGAAAGGCTCAACTCCTTGACCACTTCCTTGAT
TCTGGGAACGGGTGCCTATGCTCCCAAGAAAATCCTGAGTAACCAGGATCTTGAGCAGATGATCGCGACAACCGATCAAT
GGATCACCGAGCGAACCGGCATCAAGACACGCCATATCGCCGCTGAAGGGGAAACCACCTCCGATATGGCGGTTTGCGCG
GCGCGGGAAGCTCTAGCGCTCGCTGGAACCAGCGCCGAGGAGCTCGACATGATCATCGTCGGCACGATTTCCGCCGACAT
GCCTTTGCCCTCCTGTGCTGTGCTTATTCAGGCCAAACTCGGTGCGCGCAATGCTTTCGCCTTCGATCTTTCGGCCGCTT
GTGCCGGCTCGCTCTATGGCATGAGCATCGCCGATCAATTCATTCGCTCGGGCAAGGCACGCCGCGTTCTCGTCATCGGC
GCCGAATTACTGAGCCGGCTCATCGACTGGAGTGATCGCAATACCTGTATCCTGTTTGGCGATGGGGCTGGTGCCGTGGT
CATGGGACCCTGCGAGGATCCACAACGCGGGCTTTTATCCACGCATCTCCATACCGATGGCAGCACCGCCGATCTGTTGA
AAATTCCAGGAGGCGGCAGCCTGCATCCGCAATCCGAGGAAGTGCTTGCGAACAAATGGCATAAGGTCGCCATGAACGGG
CGGGAAATCTATAAATTCGCCGCCAAGGTGCTGCCGCTCGCTCTCAATGAAGCTCTGCAGGCCAATGGATTGCAGGCGAA
TGACGTGGATCATGTCATCGCGCATCAAGCCAATGCGCGTATTGTCGAAACCGTGCTGGAAAGGGTCGGTATTCCGCAGG
AAAAATGCTGGCTCAATCTCGATCGTTACGGCAATACATCGAGTGCATCTCTACCCATTTCCCTCGACGAGGCCAATCGT
GCCGGCCGTCTGCGGCCTGGTGACCTCATTGCCATGATGGCCATTGGCGCTGGTATGGCCTGGGGCAGCGCTCTGTTGCG
CTGGTAG

Upstream 100 bases:

>100_bases
AGAAGAGCCCACTTTTGAATTTGATGCTTTAGTCTTTGTCGATCGAATCTTCCCGGCCTTGCCTCGGGCGGGGGGATTTT
ATATCCAATGGCCCGTTCGT

Downstream 100 bases:

>100_bases
CGCCACCCTCTTCTCTCCACACCCTGTTTTCCTCCAAGGGGTGAGAGGGGGCGTGACATGATGGCGCGATGGGATGGGTC
ATCGCTGTGAAAACACGTGT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MGTIIFLLTTGPHDRPERLNSLTTSLILGTGAYAPKKILSNQDLEQMIATTDQWITERTGIKTRHIAAEGETTSDMAVCA
AREALALAGTSAEELDMIIVGTISADMPLPSCAVLIQAKLGARNAFAFDLSAACAGSLYGMSIADQFIRSGKARRVLVIG
AELLSRLIDWSDRNTCILFGDGAGAVVMGPCEDPQRGLLSTHLHTDGSTADLLKIPGGGSLHPQSEEVLANKWHKVAMNG
REIYKFAAKVLPLALNEALQANGLQANDVDHVIAHQANARIVETVLERVGIPQEKCWLNLDRYGNTSSASLPISLDEANR
AGRLRPGDLIAMMAIGAGMAWGSALLRW

Sequences:

>Translated_348_residues
MGTIIFLLTTGPHDRPERLNSLTTSLILGTGAYAPKKILSNQDLEQMIATTDQWITERTGIKTRHIAAEGETTSDMAVCA
AREALALAGTSAEELDMIIVGTISADMPLPSCAVLIQAKLGARNAFAFDLSAACAGSLYGMSIADQFIRSGKARRVLVIG
AELLSRLIDWSDRNTCILFGDGAGAVVMGPCEDPQRGLLSTHLHTDGSTADLLKIPGGGSLHPQSEEVLANKWHKVAMNG
REIYKFAAKVLPLALNEALQANGLQANDVDHVIAHQANARIVETVLERVGIPQEKCWLNLDRYGNTSSASLPISLDEANR
AGRLRPGDLIAMMAIGAGMAWGSALLRW
>Mature_347_residues
GTIIFLLTTGPHDRPERLNSLTTSLILGTGAYAPKKILSNQDLEQMIATTDQWITERTGIKTRHIAAEGETTSDMAVCAA
REALALAGTSAEELDMIIVGTISADMPLPSCAVLIQAKLGARNAFAFDLSAACAGSLYGMSIADQFIRSGKARRVLVIGA
ELLSRLIDWSDRNTCILFGDGAGAVVMGPCEDPQRGLLSTHLHTDGSTADLLKIPGGGSLHPQSEEVLANKWHKVAMNGR
EIYKFAAKVLPLALNEALQANGLQANDVDHVIAHQANARIVETVLERVGIPQEKCWLNLDRYGNTSSASLPISLDEANRA
GRLRPGDLIAMMAIGAGMAWGSALLRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=44.4099378881988, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37176; Mature: 37045

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTIIFLLTTGPHDRPERLNSLTTSLILGTGAYAPKKILSNQDLEQMIATTDQWITERTG
CCEEEEEEECCCCCCHHHHHHHHHHHHEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHCC
IKTRHIAAEGETTSDMAVCAAREALALAGTSAEELDMIIVGTISADMPLPSCAVLIQAKL
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHCCEEEEEEEECCCCCCHHHHHEEHHC
GARNAFAFDLSAACAGSLYGMSIADQFIRSGKARRVLVIGAELLSRLIDWSDRNTCILFG
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEE
DGAGAVVMGPCEDPQRGLLSTHLHTDGSTADLLKIPGGGSLHPQSEEVLANKWHKVAMNG
CCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCH
REIYKFAAKVLPLALNEALQANGLQANDVDHVIAHQANARIVETVLERVGIPQEKCWLNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHEEEH
DRYGNTSSASLPISLDEANRAGRLRPGDLIAMMAIGAGMAWGSALLRW
HCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
GTIIFLLTTGPHDRPERLNSLTTSLILGTGAYAPKKILSNQDLEQMIATTDQWITERTG
CEEEEEEECCCCCCHHHHHHHHHHHHEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHCC
IKTRHIAAEGETTSDMAVCAAREALALAGTSAEELDMIIVGTISADMPLPSCAVLIQAKL
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHCCEEEEEEEECCCCCCHHHHHEEHHC
GARNAFAFDLSAACAGSLYGMSIADQFIRSGKARRVLVIGAELLSRLIDWSDRNTCILFG
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEE
DGAGAVVMGPCEDPQRGLLSTHLHTDGSTADLLKIPGGGSLHPQSEEVLANKWHKVAMNG
CCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCH
REIYKFAAKVLPLALNEALQANGLQANDVDHVIAHQANARIVETVLERVGIPQEKCWLNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHEEEH
DRYGNTSSASLPISLDEANRAGRLRPGDLIAMMAIGAGMAWGSALLRW
HCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA