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The map label for this gene is metI [H]

Identifier: 182679408

GI number: 182679408

Start: 2802442

End: 2803104

Strand: Reverse

Name: metI [H]

Synonym: Bind_2456

Alternate gene names: 182679408

Gene position: 2803104-2802442 (Counterclockwise)

Preceding gene: 182679409

Following gene: 182679407

Centisome position: 67.22

GC content: 59.88

Gene sequence:

>663_bases
ATGTCGCCTGAGATCTTCCAACTCATCTATGATGCCCTGCTTGAAACCCTTTTCATGGTCATGTCGGCGGCTTTTCTTGG
CTCACTCTTCGGCCTACCGCTCGGTCTCTTTCTCGCCACCAGCCGCCACGGAGAATTGCTTTCGGCCCCTCTCGTCAACA
AAGGACTGGGGCTCATCGTCAATGCGACGCGTTCAGTCCCATTCATCATCCTCGTCGTCGCGCTGATCCCTGTTACGCGG
GCCATTGCCGGCACTTCGATCGGGACGCGCTCAGCAATCGTTCCCCTCACGATCGCTGCGACGCCCTTCATCGCCCGTCT
CGTCGAGACGGCGATCCGCGAGGTCGATCGGGGGCTGATTGAGGCGGCCCGTGCGATGGGCGCGACGCCCGTCCAAATTA
TCGTGAAAATTCTTTTGCCGGAGGCGATCCCCTCGATTGTCTCAAGCCTCACGCTCGCGGTCGTGAGCCTTATCGGCTAC
TCGGCCATGGCGGGCACAGTGGGCGGCGGCGGCCTCGGCGATCTTGGCATTCGCTATGGTTATCAGCGCTTCATGCCGGA
TGTGATGGTGGCGGTGGTTCTCGTTCTCATTCTGCTCGTGCAAGGCGTCCAGACATTTGGCGACACTTGGGCGCGACGAG
TCAACAAACGGATCCGGCATTAA

Upstream 100 bases:

>100_bases
TTCGGGACACTCATCATTGGCCTGCCTGCAGGTGAGGCCCTAGCCAACCAGGCCCGCCATTTCCTGTCCGAGCGAGGCCA
TGACGCGGAGTTTCTCGGTT

Downstream 100 bases:

>100_bases
ACCATCGAGCCGAAAGTGGGCGTCCGATCTTAATCCAAATCGATGTGATGAGAGAGTGATGAATTCGACCACAACTCACG
CCAAGGCTGCCCGCTTGCTC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSPEIFQLIYDALLETLFMVMSAAFLGSLFGLPLGLFLATSRHGELLSAPLVNKGLGLIVNATRSVPFIILVVALIPVTR
AIAGTSIGTRSAIVPLTIAATPFIARLVETAIREVDRGLIEAARAMGATPVQIIVKILLPEAIPSIVSSLTLAVVSLIGY
SAMAGTVGGGGLGDLGIRYGYQRFMPDVMVAVVLVLILLVQGVQTFGDTWARRVNKRIRH

Sequences:

>Translated_220_residues
MSPEIFQLIYDALLETLFMVMSAAFLGSLFGLPLGLFLATSRHGELLSAPLVNKGLGLIVNATRSVPFIILVVALIPVTR
AIAGTSIGTRSAIVPLTIAATPFIARLVETAIREVDRGLIEAARAMGATPVQIIVKILLPEAIPSIVSSLTLAVVSLIGY
SAMAGTVGGGGLGDLGIRYGYQRFMPDVMVAVVLVLILLVQGVQTFGDTWARRVNKRIRH
>Mature_219_residues
SPEIFQLIYDALLETLFMVMSAAFLGSLFGLPLGLFLATSRHGELLSAPLVNKGLGLIVNATRSVPFIILVVALIPVTRA
IAGTSIGTRSAIVPLTIAATPFIARLVETAIREVDRGLIEAARAMGATPVQIIVKILLPEAIPSIVSSLTLAVVSLIGYS
AMAGTVGGGGLGDLGIRYGYQRFMPDVMVAVVLVLILLVQGVQTFGDTWARRVNKRIRH

Specific function: Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=217, Percent_Identity=47.926267281106, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1788451, Length=179, Percent_Identity=29.608938547486, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23304; Mature: 23173

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEIFQLIYDALLETLFMVMSAAFLGSLFGLPLGLFLATSRHGELLSAPLVNKGLGLIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCHHEE
NATRSVPFIILVVALIPVTRAIAGTSIGTRSAIVPLTIAATPFIARLVETAIREVDRGLI
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAARAMGATPVQIIVKILLPEAIPSIVSSLTLAVVSLIGYSAMAGTVGGGGLGDLGIRYG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
YQRFMPDVMVAVVLVLILLVQGVQTFGDTWARRVNKRIRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPEIFQLIYDALLETLFMVMSAAFLGSLFGLPLGLFLATSRHGELLSAPLVNKGLGLIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCHHEE
NATRSVPFIILVVALIPVTRAIAGTSIGTRSAIVPLTIAATPFIARLVETAIREVDRGLI
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAARAMGATPVQIIVKILLPEAIPSIVSSLTLAVVSLIGYSAMAGTVGGGGLGDLGIRYG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
YQRFMPDVMVAVVLVLILLVQGVQTFGDTWARRVNKRIRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]