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The map label for this gene is engA [H]

Identifier: 182679273

GI number: 182679273

Start: 2652601

End: 2654013

Strand: Reverse

Name: engA [H]

Synonym: Bind_2317

Alternate gene names: 182679273

Gene position: 2654013-2652601 (Counterclockwise)

Preceding gene: 182679274

Following gene: 182679272

Centisome position: 63.64

GC content: 63.2

Gene sequence:

>1413_bases
ATGCTGACCATTGCCATTATCGGCCGTCCCAATGTCGGCAAGTCCACGCTGTTTAACCGCCTTGTCGGCAAGAAACTGGC
GCTCGTCGATGATCGGCCAGGGGTCACGCGCGACCGCCGCGAGGGGGATGCCAAACTTGGCGATCTGACCTTCAAGATCA
TCGATACGGCCGGATTGGAGGAAGGGCATGAGGAGACCCTCTCCGGGCGCATGCGGGCGCAGACCGAGGCGGCGATCGAA
CAGGCCGATGGCATTTTCTTCTTGTTCGACGCGCGCGTGGGCCTGACGCCTGAAGATCGTTTCTTCGCGCAGCTCGTGCG
CCGTGCCGGTAAGCCCCTGGTGCTTATCGCCAATAAGGCGGAGGGCCGGGTCGGCACAGCGGGCGCGATCGAGGGGTTTG
ACCTCGGCCTTGGCGATCCCGTCCCGCTCTCGGCGGAGCATGGCGAAGGGCTCGCCGATCTCTATGAGGCCTTGCGCGAA
AACTGGCCCGAGGAGACAGAGGCGCCGGATGAGGCGGGCCCGGCCGAAGAGCGTCTGACACTTGGCGAGGATGAAGACGG
GTCCGAACTCGATCTGACCAAGCCTTTGCGCATTGCCGTGGTCGGGCGGCCGAATGCGGGCAAATCGACTTTGCTCAACC
GCCTGCTTGGCGAGGAGCGCCTGCTTACGGGGCCGGAAGCGGGCCTGACACGCGATTCGATTGGTCTCGATCTCGAATGG
CGTGGCCGCAAGATGAAGATTTTCGATACGGCGGGCCTGCGCCGCCGTGCCAAGATCGAGGACAAGCTGGAAAAGCTCGC
CGCCGCCGATGCCCTGCGCGCCGTGCGCTTCGCCGAAGTGGTGGTGGTGCTTCTCGATGCCACCATTCCTTTTGAGAAAC
AGGATCTGACCATTGCCGATCTCGTCGAGCGCGAGGGCAGGGCCTTGGTCATCGCCCTCAACAAATGGGATCTAATCGGC
GCTGATGACGCCGAAAGGGCGGCGCGGCTTACGCTTTTGCGCGAGGAAGCCGGGCGGCTCCTGCCGCAGGTCAAGGGCAC
GCCGGTCGTTCCGGTTTCCGCGACGACCGCCGAGGGGCTCGACAGGCTGATGGCGGCGATCGACAAGGTGCATGTCATCT
GGAACAAGAGAATTGCGACGGCGCGGCTCAATCGCTGGCTTGAGGGCGCTCTGGAACAGACGCCGCCACCTGCCGTTTCC
GGCCGCCGGATCAAGATCCGCTACATGACCCAATTGCGCGCCCGTCCGCCCTATTTCCTGCTGTTTGGCAATCAGCTCGA
CGCCTTGCCCACGAGCTATGAGCGTTTTCTCGTTAATGGCTTGCGCCAGGCCTTTGACTTGCCGGGCGTGCCGATTCGCT
TGTCGAAAAAGACCACCGACAATCCCTATGCGTCACGCAAGGCGCGCAAGTGA

Upstream 100 bases:

>100_bases
CCGCTCCCAAACCCGAGAGCAAACCGGAAACCAAGGAGCAAACCCCGTCGGGAGCTGTTCCCGCGCCTGAAAAAACCTCG
ACGGAGACTGGCAAGCCATA

Downstream 100 bases:

>100_bases
ACGGGCAAGTGCAAGTGAACGGGCAAGTCAATGTGCGCCTGAGCGGGCTTTCATCCGGCTCGCCAGTTGCTTGCGTTGAG
CCTATTCTCGACATTGCGGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MLTIAIIGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDAKLGDLTFKIIDTAGLEEGHEETLSGRMRAQTEAAIE
QADGIFFLFDARVGLTPEDRFFAQLVRRAGKPLVLIANKAEGRVGTAGAIEGFDLGLGDPVPLSAEHGEGLADLYEALRE
NWPEETEAPDEAGPAEERLTLGEDEDGSELDLTKPLRIAVVGRPNAGKSTLLNRLLGEERLLTGPEAGLTRDSIGLDLEW
RGRKMKIFDTAGLRRRAKIEDKLEKLAAADALRAVRFAEVVVVLLDATIPFEKQDLTIADLVEREGRALVIALNKWDLIG
ADDAERAARLTLLREEAGRLLPQVKGTPVVPVSATTAEGLDRLMAAIDKVHVIWNKRIATARLNRWLEGALEQTPPPAVS
GRRIKIRYMTQLRARPPYFLLFGNQLDALPTSYERFLVNGLRQAFDLPGVPIRLSKKTTDNPYASRKARK

Sequences:

>Translated_470_residues
MLTIAIIGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDAKLGDLTFKIIDTAGLEEGHEETLSGRMRAQTEAAIE
QADGIFFLFDARVGLTPEDRFFAQLVRRAGKPLVLIANKAEGRVGTAGAIEGFDLGLGDPVPLSAEHGEGLADLYEALRE
NWPEETEAPDEAGPAEERLTLGEDEDGSELDLTKPLRIAVVGRPNAGKSTLLNRLLGEERLLTGPEAGLTRDSIGLDLEW
RGRKMKIFDTAGLRRRAKIEDKLEKLAAADALRAVRFAEVVVVLLDATIPFEKQDLTIADLVEREGRALVIALNKWDLIG
ADDAERAARLTLLREEAGRLLPQVKGTPVVPVSATTAEGLDRLMAAIDKVHVIWNKRIATARLNRWLEGALEQTPPPAVS
GRRIKIRYMTQLRARPPYFLLFGNQLDALPTSYERFLVNGLRQAFDLPGVPIRLSKKTTDNPYASRKARK
>Mature_470_residues
MLTIAIIGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDAKLGDLTFKIIDTAGLEEGHEETLSGRMRAQTEAAIE
QADGIFFLFDARVGLTPEDRFFAQLVRRAGKPLVLIANKAEGRVGTAGAIEGFDLGLGDPVPLSAEHGEGLADLYEALRE
NWPEETEAPDEAGPAEERLTLGEDEDGSELDLTKPLRIAVVGRPNAGKSTLLNRLLGEERLLTGPEAGLTRDSIGLDLEW
RGRKMKIFDTAGLRRRAKIEDKLEKLAAADALRAVRFAEVVVVLLDATIPFEKQDLTIADLVEREGRALVIALNKWDLIG
ADDAERAARLTLLREEAGRLLPQVKGTPVVPVSATTAEGLDRLMAAIDKVHVIWNKRIATARLNRWLEGALEQTPPPAVS
GRRIKIRYMTQLRARPPYFLLFGNQLDALPTSYERFLVNGLRQAFDLPGVPIRLSKKTTDNPYASRKARK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=476, Percent_Identity=37.8151260504202, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1788919, Length=169, Percent_Identity=28.9940828402367, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI2367268, Length=174, Percent_Identity=33.9080459770115, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR001806
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51743; Mature: 51743

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTIAIIGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDAKLGDLTFKIIDTAGLE
CEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
EGHEETLSGRMRAQTEAAIEQADGIFFLFDARVGLTPEDRFFAQLVRRAGKPLVLIANKA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECC
EGRVGTAGAIEGFDLGLGDPVPLSAEHGEGLADLYEALRENWPEETEAPDEAGPAEERLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCC
LGEDEDGSELDLTKPLRIAVVGRPNAGKSTLLNRLLGEERLLTGPEAGLTRDSIGLDLEW
CCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
RGRKMKIFDTAGLRRRAKIEDKLEKLAAADALRAVRFAEVVVVLLDATIPFEKQDLTIAD
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LVEREGRALVIALNKWDLIGADDAERAARLTLLREEAGRLLPQVKGTPVVPVSATTAEGL
HHHCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHH
DRLMAAIDKVHVIWNKRIATARLNRWLEGALEQTPPPAVSGRRIKIRYMTQLRARPPYFL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHCCCCCEEE
LFGNQLDALPTSYERFLVNGLRQAFDLPGVPIRLSKKTTDNPYASRKARK
EECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTIAIIGRPNVGKSTLFNRLVGKKLALVDDRPGVTRDRREGDAKLGDLTFKIIDTAGLE
CEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
EGHEETLSGRMRAQTEAAIEQADGIFFLFDARVGLTPEDRFFAQLVRRAGKPLVLIANKA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECC
EGRVGTAGAIEGFDLGLGDPVPLSAEHGEGLADLYEALRENWPEETEAPDEAGPAEERLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCC
LGEDEDGSELDLTKPLRIAVVGRPNAGKSTLLNRLLGEERLLTGPEAGLTRDSIGLDLEW
CCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
RGRKMKIFDTAGLRRRAKIEDKLEKLAAADALRAVRFAEVVVVLLDATIPFEKQDLTIAD
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LVEREGRALVIALNKWDLIGADDAERAARLTLLREEAGRLLPQVKGTPVVPVSATTAEGL
HHHCCCCEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHH
DRLMAAIDKVHVIWNKRIATARLNRWLEGALEQTPPPAVSGRRIKIRYMTQLRARPPYFL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHCCCCCEEE
LFGNQLDALPTSYERFLVNGLRQAFDLPGVPIRLSKKTTDNPYASRKARK
EECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA