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The map label for this gene is ubiA [H]

Identifier: 182679207

GI number: 182679207

Start: 2581762

End: 2582730

Strand: Reverse

Name: ubiA [H]

Synonym: Bind_2247

Alternate gene names: 182679207

Gene position: 2582730-2581762 (Counterclockwise)

Preceding gene: 182679208

Following gene: 182679206

Centisome position: 61.93

GC content: 59.55

Gene sequence:

>969_bases
ATGCCTATGGAAGGCGGGACCGAGCCTTTCGGTTCACCGATCGGTGCTGCGGCCGTGCTCCCGGATGCCGCGCCGGACCA
ATGGCTTTTCCGGTTTTCGCCGCCCGCAGCACATCCCTATTTGCAGCTCGCGCGCCTCGACAGGCCGGTTGGCTGGTGGC
TTCTGCTGCTGCCCTGCTGGTGGGGGAGTGCTCTGGCAAGCCTGGCAGCGGGCGTGCCTTTGCACTGGGCGCATCTCCTC
CTGTTTCTGATTGGCGCCATCGTCATGCGGGGCGCGGGCTCTACCTTTAATGACATCGTCGATCGCGAAGTGGATGCGAA
AGTCGAACGCACGAGAATGCGGCCCTTGCCGTCTGGCCGCGTCAGTGTTCTGGGCGCGCAAGGTTTTTTCCTGTTGCAGT
CGCTCATCGGCCTCGCCGTTTTGCTGAGCTTCAATCTGTTCACGATTGTTCTAGGTCTCTCCTCCCTCGTTTTCGTCGCG
ATCTATCCCTTTATGAAACGCGTGACCTCCTGGCCACAGGCGGTCCTTGGCTGCGCTTTTGCCTGGGGCATTTTGATGGG
ATGGGCGGCGGCTTTCGGCTCGCTTTCTTTAGCCCCGGTCCAGCTTTACTTGGGCGGCATAGCCTGGACGATCGGTTATG
ACACGATCTATGCGATCCAGGACATTCGGGACGATGTTAAGGCGGGGGTCAAATCGACGGCGCGCTTGTTTGGGACGCGT
ATCCGTCTCTGTGTTGGCCTTCTCTATGGCCTGACTTTGCTGCTGTCCGCCGGAGCTCTGTGGGTTGCCGGGGCCTTGCA
CGGTTTAGCGCTCATCGGGTGGATTGGCTTTGCGCTGCATCTTGGGTGGCAGGTCAAAAGCATTGATCTGGAGAATGTAG
GCCAGGCCCTGCGCCTCTTCCGTTCCAACAGGGATGCCGGGCTTTTGTTCTTTATCGGTCTCGCTGCGCAATCGATTTTA
TCGACTTGA

Upstream 100 bases:

>100_bases
GCGCGGTCGCTGCGCAGGTCAAGAAGGCGCAAAGCCAGCAGGCCGCTGGTGGCGGCGCACTTAATGTGCCGCAGCAGAAA
TTGCCGACAGGCCCACTTTG

Downstream 100 bases:

>100_bases
TCGATCATGGCCTTTGGCGCGGGAACGTTCGTTTCCAGCACGGCGTTGTATTTGGCGGCGTTGCTTGTCAGACGAATGGA
AGGCGGATTACGTGGGGCCG

Product: 4-hydroxybenzoate polyprenyl transferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPMEGGTEPFGSPIGAAAVLPDAAPDQWLFRFSPPAAHPYLQLARLDRPVGWWLLLLPCWWGSALASLAAGVPLHWAHLL
LFLIGAIVMRGAGSTFNDIVDREVDAKVERTRMRPLPSGRVSVLGAQGFFLLQSLIGLAVLLSFNLFTIVLGLSSLVFVA
IYPFMKRVTSWPQAVLGCAFAWGILMGWAAAFGSLSLAPVQLYLGGIAWTIGYDTIYAIQDIRDDVKAGVKSTARLFGTR
IRLCVGLLYGLTLLLSAGALWVAGALHGLALIGWIGFALHLGWQVKSIDLENVGQALRLFRSNRDAGLLFFIGLAAQSIL
ST

Sequences:

>Translated_322_residues
MPMEGGTEPFGSPIGAAAVLPDAAPDQWLFRFSPPAAHPYLQLARLDRPVGWWLLLLPCWWGSALASLAAGVPLHWAHLL
LFLIGAIVMRGAGSTFNDIVDREVDAKVERTRMRPLPSGRVSVLGAQGFFLLQSLIGLAVLLSFNLFTIVLGLSSLVFVA
IYPFMKRVTSWPQAVLGCAFAWGILMGWAAAFGSLSLAPVQLYLGGIAWTIGYDTIYAIQDIRDDVKAGVKSTARLFGTR
IRLCVGLLYGLTLLLSAGALWVAGALHGLALIGWIGFALHLGWQVKSIDLENVGQALRLFRSNRDAGLLFFIGLAAQSIL
ST
>Mature_321_residues
PMEGGTEPFGSPIGAAAVLPDAAPDQWLFRFSPPAAHPYLQLARLDRPVGWWLLLLPCWWGSALASLAAGVPLHWAHLLL
FLIGAIVMRGAGSTFNDIVDREVDAKVERTRMRPLPSGRVSVLGAQGFFLLQSLIGLAVLLSFNLFTIVLGLSSLVFVAI
YPFMKRVTSWPQAVLGCAFAWGILMGWAAAFGSLSLAPVQLYLGGIAWTIGYDTIYAIQDIRDDVKAGVKSTARLFGTRI
RLCVGLLYGLTLLLSAGALWVAGALHGLALIGWIGFALHLGWQVKSIDLENVGQALRLFRSNRDAGLLFFIGLAAQSILS
T

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=314, Percent_Identity=41.4012738853503, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1790473, Length=283, Percent_Identity=40.2826855123675, Blast_Score=160, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17553718, Length=289, Percent_Identity=40.4844290657439, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI32565247, Length=290, Percent_Identity=37.9310344827586, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17553720, Length=357, Percent_Identity=31.3725490196078, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32565245, Length=145, Percent_Identity=45.5172413793103, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI32565243, Length=144, Percent_Identity=45.1388888888889, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=300, Percent_Identity=40.3333333333333, Blast_Score=182, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21355567, Length=289, Percent_Identity=46.0207612456747, Blast_Score=223, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34712; Mature: 34581

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMEGGTEPFGSPIGAAAVLPDAAPDQWLFRFSPPAAHPYLQLARLDRPVGWWLLLLPCW
CCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHH
WGSALASLAAGVPLHWAHLLLFLIGAIVMRGAGSTFNDIVDREVDAKVERTRMRPLPSGR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VSVLGAQGFFLLQSLIGLAVLLSFNLFTIVLGLSSLVFVAIYPFMKRVTSWPQAVLGCAF
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWGILMGWAAAFGSLSLAPVQLYLGGIAWTIGYDTIYAIQDIRDDVKAGVKSTARLFGTR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLCVGLLYGLTLLLSAGALWVAGALHGLALIGWIGFALHLGWQVKSIDLENVGQALRLF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHH
RSNRDAGLLFFIGLAAQSILST
HCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PMEGGTEPFGSPIGAAAVLPDAAPDQWLFRFSPPAAHPYLQLARLDRPVGWWLLLLPCW
CCCCCCCCCCCCCCHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHH
WGSALASLAAGVPLHWAHLLLFLIGAIVMRGAGSTFNDIVDREVDAKVERTRMRPLPSGR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VSVLGAQGFFLLQSLIGLAVLLSFNLFTIVLGLSSLVFVAIYPFMKRVTSWPQAVLGCAF
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWGILMGWAAAFGSLSLAPVQLYLGGIAWTIGYDTIYAIQDIRDDVKAGVKSTARLFGTR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRLCVGLLYGLTLLLSAGALWVAGALHGLALIGWIGFALHLGWQVKSIDLENVGQALRLF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHH
RSNRDAGLLFFIGLAAQSILST
HCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA