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The map label for this gene is ytfL [C]

Identifier: 182679195

GI number: 182679195

Start: 2561065

End: 2562396

Strand: Reverse

Name: ytfL [C]

Synonym: Bind_2234

Alternate gene names: 182679195

Gene position: 2562396-2561065 (Counterclockwise)

Preceding gene: 182679200

Following gene: 182679181

Centisome position: 61.45

GC content: 58.56

Gene sequence:

>1332_bases
ATGGGCGATGGCAGTAGTCTGAGTGATATCCTCGGGATTCTTGCTGTTTTCCTGCTGGTCTTCGCCAATGGTTTTTTCGT
CGCCGCCGAATTCGCGCTGGTCTCGGTCCGGCGGAGCCGCGTGGCCGAACTCGTGGCCGCCAAGCGCGTCAATGCGTTGA
GCCTGCAAACGACTCTCAACCATCTGGATCTCAATCTCGCCGCGACTCAGCTCGGCGTCACCATTTCCTCGCTCGGCCTT
GGCTGGATCGGCGAACCGGCCCTGGCGCATCTCATCGAGCCTCTGTTCAGCGCCTTGCCGCGTGACTGGATGTCCGCCGG
CTCGCACGCAATCTCCGTCGCCATTTCCTTCATCATCATCACCGCCTTGCATATTGTGCTCGGTGAATTGGCTCCCAAAA
GCCTTGCTCTGCAGCGAACGGAACGGACCGCGCTTTTCGTCGTCGGCCCCCTCAATGTGTTCCAATTCGTCCTGCGACCG
GCGATTATAGCCTTGAATACGCTTGGTAATATGGTTTTGCGCATCGTTGGTCTTCAGGCTGGAAAGGGCGAGGAATCACG
CCATTCCCCGGAAGAGTTGAAATTGCTGGTCGCGGCGAGCCGCAAGGCCGGTTTGCTGCAGGAAGCGCAGCAGGAAGTTC
TCGACCGCGTGTTCAATATCGGGCAGCGCCGGATCGGCGATATTATGACGCCTCGCGTCGATCTCGATTGGATTGATCTC
GACGATAAGCCGGATGACATTCTCAAATCGATTCGGGAATGCCGGCACGAGCAATTACTGGCTGGACGCGGCAATATCGA
CGAGCCGCTTGGCATGGTTTCCAAGAAGGAATTGCTCGATCAGGTTCTCGACGGGGGGCAGATTAATGCCGCCGCGGCTC
TGCGCGAGCCGCTCGTCGTGCATGAATCGACGCCGGTGTTTCGTGTGCTGGAGCAATTCAAGCGCGCGCCGGTCAGGCTG
GCTTTGGTCGTGGATGAATATGGCAGTCTCGAAGGGATTGTGACGCAGACCGATCTTCTGGAAGCGATCGCCGGCGATCT
CGCCGCCACGGAGGATGATACTCCCGATATTGTCGAGCGCGCGGATGGTTCCCTCCTGATCGAGGGCATGATGCCAGCGC
ATGAGGCTTTTGAGCGTCTGGGCGTCAAGGATCGGCCGGAGGAGGAAGATTATCACACGCTCGCTGGTTTTGCCCTGCAC
CAGCTCGAACATCTTCCAGAGGTCGGCGAGGAATTCTCGTGGGATGGCTGGCGTTTCGAGATCGTCGACATGGACGGGCG
CCGGATCGATAAATTGCTCGCGACGCGCGAGAGCGAATCGAAAAGCTTATGA

Upstream 100 bases:

>100_bases
CCTTCCGCCCGGCTGAAAAAAGCGAGTTTGATCACGGGCTTTATATTTCCGATAATGGCCCTTTACATGCATCCTGCTCA
AGGAAAAGGAGATGACGCCC

Downstream 100 bases:

>100_bases
CCTTTGTTCGTCCTGACTTGTGAGCAAGGCGTCGAGCCTTGCTTGCTCGGCGGGATCGAGGGGAACAGCCTGATGTGAGT
CTTCCGCTCCTCTTCGGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MGDGSSLSDILGILAVFLLVFANGFFVAAEFALVSVRRSRVAELVAAKRVNALSLQTTLNHLDLNLAATQLGVTISSLGL
GWIGEPALAHLIEPLFSALPRDWMSAGSHAISVAISFIIITALHIVLGELAPKSLALQRTERTALFVVGPLNVFQFVLRP
AIIALNTLGNMVLRIVGLQAGKGEESRHSPEELKLLVAASRKAGLLQEAQQEVLDRVFNIGQRRIGDIMTPRVDLDWIDL
DDKPDDILKSIRECRHEQLLAGRGNIDEPLGMVSKKELLDQVLDGGQINAAAALREPLVVHESTPVFRVLEQFKRAPVRL
ALVVDEYGSLEGIVTQTDLLEAIAGDLAATEDDTPDIVERADGSLLIEGMMPAHEAFERLGVKDRPEEEDYHTLAGFALH
QLEHLPEVGEEFSWDGWRFEIVDMDGRRIDKLLATRESESKSL

Sequences:

>Translated_443_residues
MGDGSSLSDILGILAVFLLVFANGFFVAAEFALVSVRRSRVAELVAAKRVNALSLQTTLNHLDLNLAATQLGVTISSLGL
GWIGEPALAHLIEPLFSALPRDWMSAGSHAISVAISFIIITALHIVLGELAPKSLALQRTERTALFVVGPLNVFQFVLRP
AIIALNTLGNMVLRIVGLQAGKGEESRHSPEELKLLVAASRKAGLLQEAQQEVLDRVFNIGQRRIGDIMTPRVDLDWIDL
DDKPDDILKSIRECRHEQLLAGRGNIDEPLGMVSKKELLDQVLDGGQINAAAALREPLVVHESTPVFRVLEQFKRAPVRL
ALVVDEYGSLEGIVTQTDLLEAIAGDLAATEDDTPDIVERADGSLLIEGMMPAHEAFERLGVKDRPEEEDYHTLAGFALH
QLEHLPEVGEEFSWDGWRFEIVDMDGRRIDKLLATRESESKSL
>Mature_442_residues
GDGSSLSDILGILAVFLLVFANGFFVAAEFALVSVRRSRVAELVAAKRVNALSLQTTLNHLDLNLAATQLGVTISSLGLG
WIGEPALAHLIEPLFSALPRDWMSAGSHAISVAISFIIITALHIVLGELAPKSLALQRTERTALFVVGPLNVFQFVLRPA
IIALNTLGNMVLRIVGLQAGKGEESRHSPEELKLLVAASRKAGLLQEAQQEVLDRVFNIGQRRIGDIMTPRVDLDWIDLD
DKPDDILKSIRECRHEQLLAGRGNIDEPLGMVSKKELLDQVLDGGQINAAAALREPLVVHESTPVFRVLEQFKRAPVRLA
LVVDEYGSLEGIVTQTDLLEAIAGDLAATEDDTPDIVERADGSLLIEGMMPAHEAFERLGVKDRPEEEDYHTLAGFALHQ
LEHLPEVGEEFSWDGWRFEIVDMDGRRIDKLLATRESESKSL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=375, Percent_Identity=32.8, Blast_Score=213, Evalue=4e-55,
Organism=Escherichia coli, GI1790664, Length=428, Percent_Identity=27.803738317757, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87082033, Length=262, Percent_Identity=32.0610687022901, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI145693175, Length=328, Percent_Identity=27.4390243902439, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=28.6919831223629, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786879, Length=242, Percent_Identity=29.7520661157025, Blast_Score=89, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48533; Mature: 48402

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDGSSLSDILGILAVFLLVFANGFFVAAEFALVSVRRSRVAELVAAKRVNALSLQTTLN
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HLDLNLAATQLGVTISSLGLGWIGEPALAHLIEPLFSALPRDWMSAGSHAISVAISFIII
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHH
TALHIVLGELAPKSLALQRTERTALFVVGPLNVFQFVLRPAIIALNTLGNMVLRIVGLQA
HHHHHHHHHCCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKGEESRHSPEELKLLVAASRKAGLLQEAQQEVLDRVFNIGQRRIGDIMTPRVDLDWIDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DDKPDDILKSIRECRHEQLLAGRGNIDEPLGMVSKKELLDQVLDGGQINAAAALREPLVV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEE
HESTPVFRVLEQFKRAPVRLALVVDEYGSLEGIVTQTDLLEAIAGDLAATEDDTPDIVER
ECCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ADGSLLIEGMMPAHEAFERLGVKDRPEEEDYHTLAGFALHQLEHLPEVGEEFSWDGWRFE
CCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVDMDGRRIDKLLATRESESKSL
EEECCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GDGSSLSDILGILAVFLLVFANGFFVAAEFALVSVRRSRVAELVAAKRVNALSLQTTLN
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HLDLNLAATQLGVTISSLGLGWIGEPALAHLIEPLFSALPRDWMSAGSHAISVAISFIII
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHH
TALHIVLGELAPKSLALQRTERTALFVVGPLNVFQFVLRPAIIALNTLGNMVLRIVGLQA
HHHHHHHHHCCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKGEESRHSPEELKLLVAASRKAGLLQEAQQEVLDRVFNIGQRRIGDIMTPRVDLDWIDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DDKPDDILKSIRECRHEQLLAGRGNIDEPLGMVSKKELLDQVLDGGQINAAAALREPLVV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEE
HESTPVFRVLEQFKRAPVRLALVVDEYGSLEGIVTQTDLLEAIAGDLAATEDDTPDIVER
ECCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ADGSLLIEGMMPAHEAFERLGVKDRPEEEDYHTLAGFALHQLEHLPEVGEEFSWDGWRFE
CCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVDMDGRRIDKLLATRESESKSL
EEECCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]