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The map label for this gene is exbB [H]

Identifier: 182679109

GI number: 182679109

Start: 2448846

End: 2449481

Strand: Reverse

Name: exbB [H]

Synonym: Bind_2146

Alternate gene names: 182679109

Gene position: 2449481-2448846 (Counterclockwise)

Preceding gene: 182679110

Following gene: 182679108

Centisome position: 58.74

GC content: 58.18

Gene sequence:

>636_bases
ATGGAAACTCTTAGCATTTCCCCACTTTCGTTATTTGAGCAGGCGGGCCCTGTTGGCAAAGCGGTCATGGCGATTTTGCT
GCTCGCCTCCGTTTGGTGCTGGGTTCTAATTATCGAAGCGCTGGTATCTGTGTCCCGCTTAAAGAAAGCCGTTCGTCTGG
CGCGTTCTGGCGGTATTCATCCTCTCGTCGCGCCTTTGCTCGATGCTGGACAGAAGGCCGCGGCGACCACCATTCCCGGC
GAAAGTGTTGGCGAAGCACGCATACGCATTGCCGAGGCCATGCATCGCGCCGCACAGACCATTATGAAAAAAACCGAAGG
CGGATTGCCTAATCTCGCTGTCATCTCTTCGGTGGCCCCTTTCGTCGGTCTGTTCGGCACTGTCTGGGGCATTATGACGA
GCTTTACCGGCATCGCTGCGTCGAAAGATACGAGCCTCGCGGTCGTGGCGCCGGGTATTGCTGAGGCGCTTGCCGCCACG
GCCTACGGCCTTGCCGCCGCTATTCCCGCGACTTTGGGTTATAACCGCATTGGCGCCATGCTGGCGGGGCTCGGCCAGAC
GCTCAGCCATCTTGTCGAGGAACGGGCTGTCATGCTCATCAGCCGCTCATCGCAAAAATCGAAGGAGGTCGCATAA

Upstream 100 bases:

>100_bases
TTTTAAAACCGCGAACGAAAGGGCTCGCGGCCATAAAAGATTTCATGACGCCATGCTCGTTAGTCCTATAGATCCGCAAT
AATATTGGAAACCTTAACTC

Downstream 100 bases:

>100_bases
TGGCTTTTTCATCCTCTCGCGGGAGTGGGGGCGGCTATCAGCCGCTCGCTGACATTAATGTGACTCCTCTCGTTGATGTC
ATGCTGGTGCTGCTCATCGT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
METLSISPLSLFEQAGPVGKAVMAILLLASVWCWVLIIEALVSVSRLKKAVRLARSGGIHPLVAPLLDAGQKAAATTIPG
ESVGEARIRIAEAMHRAAQTIMKKTEGGLPNLAVISSVAPFVGLFGTVWGIMTSFTGIAASKDTSLAVVAPGIAEALAAT
AYGLAAAIPATLGYNRIGAMLAGLGQTLSHLVEERAVMLISRSSQKSKEVA

Sequences:

>Translated_211_residues
METLSISPLSLFEQAGPVGKAVMAILLLASVWCWVLIIEALVSVSRLKKAVRLARSGGIHPLVAPLLDAGQKAAATTIPG
ESVGEARIRIAEAMHRAAQTIMKKTEGGLPNLAVISSVAPFVGLFGTVWGIMTSFTGIAASKDTSLAVVAPGIAEALAAT
AYGLAAAIPATLGYNRIGAMLAGLGQTLSHLVEERAVMLISRSSQKSKEVA
>Mature_211_residues
METLSISPLSLFEQAGPVGKAVMAILLLASVWCWVLIIEALVSVSRLKKAVRLARSGGIHPLVAPLLDAGQKAAATTIPG
ESVGEARIRIAEAMHRAAQTIMKKTEGGLPNLAVISSVAPFVGLFGTVWGIMTSFTGIAASKDTSLAVVAPGIAEALAAT
AYGLAAAIPATLGYNRIGAMLAGLGQTLSHLVEERAVMLISRSSQKSKEVA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=222, Percent_Identity=37.3873873873874, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=31.651376146789, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 21725; Mature: 21725

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLSISPLSLFEQAGPVGKAVMAILLLASVWCWVLIIEALVSVSRLKKAVRLARSGGIH
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLVAPLLDAGQKAAATTIPGESVGEARIRIAEAMHRAAQTIMKKTEGGLPNLAVISSVAP
HHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FVGLFGTVWGIMTSFTGIAASKDTSLAVVAPGIAEALAATAYGLAAAIPATLGYNRIGAM
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGLGQTLSHLVEERAVMLISRSSQKSKEVA
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
METLSISPLSLFEQAGPVGKAVMAILLLASVWCWVLIIEALVSVSRLKKAVRLARSGGIH
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLVAPLLDAGQKAAATTIPGESVGEARIRIAEAMHRAAQTIMKKTEGGLPNLAVISSVAP
HHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FVGLFGTVWGIMTSFTGIAASKDTSLAVVAPGIAEALAATAYGLAAAIPATLGYNRIGAM
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGLGQTLSHLVEERAVMLISRSSQKSKEVA
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]