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The map label for this gene is arsC [H]

Identifier: 182679102

GI number: 182679102

Start: 2442007

End: 2442546

Strand: Reverse

Name: arsC [H]

Synonym: Bind_2139

Alternate gene names: 182679102

Gene position: 2442546-2442007 (Counterclockwise)

Preceding gene: 182679103

Following gene: 182679101

Centisome position: 58.57

GC content: 53.15

Gene sequence:

>540_bases
ATGACTGAACGCTTATGGAATGTTTTGTTTCTCTGCACAGGGAATTCAGCCCGCTCGATCCTTGCGGAAAGCATTTTGAG
AAAAGAAGGTGCAGGGAAATTCAAAGCCTTTTCCGCCGGCAGCCAACCGAAGGGCGCTGTCAATCCCTTCGCACTCAAAG
TTTTACAGAGCTTCGACTACCCGATTGAAGGCTTGCATTCCAAGAGCTGGGATGAGTTTGCGGGGCCAGAGGCTCCTGTC
ATGGATTTTATTTTCACCGTCTGCGACAATGCAGCAGGTGAGACTTGTCCAGTCTGGCCAGGACATCCAGCCACAGCGCA
TTGGGGAATTGAAGATCCAGCGGCTGTCGAAGGATCAGACCTTGAGAAGGAACGCGCCTTCGTCACAGCCTTTAGATATA
TGAAAAACAGGATCTCGGCCTTTGCCGCTTTGCCGCTGGAACAGCTCGATAGTCTTGCTTTGACTAGCAAGCTGCGGGAG
ATCGGCCAAAGCGCGGGAGCGAGTCAAGCTGCGAGTGCGCCTCATCCCGAGGTTGCCTGA

Upstream 100 bases:

>100_bases
TGCTGTTTCTTGTAAAAGATTGCTGTGGCGGTGCGACGGAAATTTGTGCGCCATTGATCGCCGATCTCATGCCGTGCTGT
CCGCCGGAAAAGGTGTCTTC

Downstream 100 bases:

>100_bases
TGAGTGCCCCCATCGACATTATCATCTACCACAATCCTGATTGCGGTACGTCGCGCAACACCTTGGCGATGATCCGCAAT
GCCGGCATCGAGCCGCATGT

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTERLWNVLFLCTGNSARSILAESILRKEGAGKFKAFSAGSQPKGAVNPFALKVLQSFDYPIEGLHSKSWDEFAGPEAPV
MDFIFTVCDNAAGETCPVWPGHPATAHWGIEDPAAVEGSDLEKERAFVTAFRYMKNRISAFAALPLEQLDSLALTSKLRE
IGQSAGASQAASAPHPEVA

Sequences:

>Translated_179_residues
MTERLWNVLFLCTGNSARSILAESILRKEGAGKFKAFSAGSQPKGAVNPFALKVLQSFDYPIEGLHSKSWDEFAGPEAPV
MDFIFTVCDNAAGETCPVWPGHPATAHWGIEDPAAVEGSDLEKERAFVTAFRYMKNRISAFAALPLEQLDSLALTSKLRE
IGQSAGASQAASAPHPEVA
>Mature_178_residues
TERLWNVLFLCTGNSARSILAESILRKEGAGKFKAFSAGSQPKGAVNPFALKVLQSFDYPIEGLHSKSWDEFAGPEAPVM
DFIFTVCDNAAGETCPVWPGHPATAHWGIEDPAAVEGSDLEKERAFVTAFRYMKNRISAFAALPLEQLDSLALTSKLREI
GQSAGASQAASAPHPEVA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 19253; Mature: 19122

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERLWNVLFLCTGNSARSILAESILRKEGAGKFKAFSAGSQPKGAVNPFALKVLQSFDY
CCHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PIEGLHSKSWDEFAGPEAPVMDFIFTVCDNAAGETCPVWPGHPATAHWGIEDPAAVEGSD
CCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
LEKERAFVTAFRYMKNRISAFAALPLEQLDSLALTSKLREIGQSAGASQAASAPHPEVA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TERLWNVLFLCTGNSARSILAESILRKEGAGKFKAFSAGSQPKGAVNPFALKVLQSFDY
CHHHEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCC
PIEGLHSKSWDEFAGPEAPVMDFIFTVCDNAAGETCPVWPGHPATAHWGIEDPAAVEGSD
CCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCC
LEKERAFVTAFRYMKNRISAFAALPLEQLDSLALTSKLREIGQSAGASQAASAPHPEVA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]