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The map label for this gene is aroD [H]

Identifier: 182679088

GI number: 182679088

Start: 2424726

End: 2425538

Strand: Reverse

Name: aroD [H]

Synonym: Bind_2125

Alternate gene names: 182679088

Gene position: 2425538-2424726 (Counterclockwise)

Preceding gene: 182679089

Following gene: 182679087

Centisome position: 58.16

GC content: 56.46

Gene sequence:

>813_bases
TTGTTGTCGAATGTTGCCGGTCTGCTTGAATGGAAAGCCGAAATGCGCGTGGTGAGCGTCAAAGATGTTGTGATCGGAGC
GGGGCGACCCAAGATCATCGTGCCCATCACGGCCAAGACTTTCAAGGATGCATTGACGTCCGCCACGCGGCTCTCAGAAG
AAAAGACGCTGGACCTCATCGAATTGCGGGTGGATTATCTTGAGAATGCGCTCGATGCTCGCGGTGTCGCGGGCCTCTTG
CGGGAAGCAGCGAAAATCCAAAATGCCAAGCCGATGATTGTGACTTTCCGAACCAAGGCGGAAGGTGGCATGACAGCGCT
CGACGGATCGAGCTATGTGGATTTTTACAAGACAATCCTCCAGGAGGGCCGGCCCGATCTGATCGATGTGGAAGTCATGC
GCGGTGATGAGATCGTGCGTGAAGTAATCGATGCTGCCCATGGTGTGGGGGTCGGTGTTATTCTTTCCAATCACGATTTC
AATGGGACAGCGCCGGCAGAGGAACTGGTCGCGCGTATGCGATCCATGCAGGATTTAGGGGCGGATATCGTCAAGATCGC
CACAATGCCTAAAGACGCGGGCGATGTTCTGCAGCTTCTCAATGCGACATGGCTCATGCACAGCCGATATGCCGAATGTC
CCTTGATCACGATGGCCATGGCGGGGCAGGGGGTGGTCTCCCGACTTTCGGGGGAAGTTTTCGGCTCGGCGGCGACATTC
GGAATGGTCGGTGAGGCCTCTGCTCCCGGCCAAGTCCAGCTTCATGAACTACGGCCGGTTCTGGATCTCATTCATGCCGC
GCTCGGGCGTTAA

Upstream 100 bases:

>100_bases
ATCGCAGATGCTGGAGACACCGAAGCCCGTATCAATCTCCTTCATCGGCGAGCATTGCATCCCTTCGCGTCGAATTGTCC
TTTGTTGCAAGGAGACGCGA

Downstream 100 bases:

>100_bases
GTTTGAAAGGATAGCCTTTCAGGCTAAATATGCCGGATTCCAGAGCATATAAATTTAAGATCCCTTTCATCAAAGAAAGA
GTATATTGAACCTCTTGTGG

Product: 3-dehydroquinate dehydratase, type I

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLSNVAGLLEWKAEMRVVSVKDVVIGAGRPKIIVPITAKTFKDALTSATRLSEEKTLDLIELRVDYLENALDARGVAGLL
REAAKIQNAKPMIVTFRTKAEGGMTALDGSSYVDFYKTILQEGRPDLIDVEVMRGDEIVREVIDAAHGVGVGVILSNHDF
NGTAPAEELVARMRSMQDLGADIVKIATMPKDAGDVLQLLNATWLMHSRYAECPLITMAMAGQGVVSRLSGEVFGSAATF
GMVGEASAPGQVQLHELRPVLDLIHAALGR

Sequences:

>Translated_270_residues
MLSNVAGLLEWKAEMRVVSVKDVVIGAGRPKIIVPITAKTFKDALTSATRLSEEKTLDLIELRVDYLENALDARGVAGLL
REAAKIQNAKPMIVTFRTKAEGGMTALDGSSYVDFYKTILQEGRPDLIDVEVMRGDEIVREVIDAAHGVGVGVILSNHDF
NGTAPAEELVARMRSMQDLGADIVKIATMPKDAGDVLQLLNATWLMHSRYAECPLITMAMAGQGVVSRLSGEVFGSAATF
GMVGEASAPGQVQLHELRPVLDLIHAALGR
>Mature_270_residues
MLSNVAGLLEWKAEMRVVSVKDVVIGAGRPKIIVPITAKTFKDALTSATRLSEEKTLDLIELRVDYLENALDARGVAGLL
REAAKIQNAKPMIVTFRTKAEGGMTALDGSSYVDFYKTILQEGRPDLIDVEVMRGDEIVREVIDAAHGVGVGVILSNHDF
NGTAPAEELVARMRSMQDLGADIVKIATMPKDAGDVLQLLNATWLMHSRYAECPLITMAMAGQGVVSRLSGEVFGSAATF
GMVGEASAPGQVQLHELRPVLDLIHAALGR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=256, Percent_Identity=46.484375, Blast_Score=224, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 29023; Mature: 29023

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNVAGLLEWKAEMRVVSVKDVVIGAGRPKIIVPITAKTFKDALTSATRLSEEKTLDLI
CCCHHHHHHHHHHHHEEEEEHHEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
ELRVDYLENALDARGVAGLLREAAKIQNAKPMIVTFRTKAEGGMTALDGSSYVDFYKTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHH
QEGRPDLIDVEVMRGDEIVREVIDAAHGVGVGVILSNHDFNGTAPAEELVARMRSMQDLG
HCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHC
ADIVKIATMPKDAGDVLQLLNATWLMHSRYAECPLITMAMAGQGVVSRLSGEVFGSAATF
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHCCHHHH
GMVGEASAPGQVQLHELRPVLDLIHAALGR
CCCCCCCCCCCEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSNVAGLLEWKAEMRVVSVKDVVIGAGRPKIIVPITAKTFKDALTSATRLSEEKTLDLI
CCCHHHHHHHHHHHHEEEEEHHEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
ELRVDYLENALDARGVAGLLREAAKIQNAKPMIVTFRTKAEGGMTALDGSSYVDFYKTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHH
QEGRPDLIDVEVMRGDEIVREVIDAAHGVGVGVILSNHDFNGTAPAEELVARMRSMQDLG
HCCCCCEEEEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHC
ADIVKIATMPKDAGDVLQLLNATWLMHSRYAECPLITMAMAGQGVVSRLSGEVFGSAATF
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHCCHHHH
GMVGEASAPGQVQLHELRPVLDLIHAALGR
CCCCCCCCCCCEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA