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The map label for this gene is nanR [H]

Identifier: 182679043

GI number: 182679043

Start: 2377499

End: 2378248

Strand: Direct

Name: nanR [H]

Synonym: Bind_2079

Alternate gene names: 182679043

Gene position: 2377499-2378248 (Clockwise)

Preceding gene: 182679042

Following gene: 182679044

Centisome position: 57.01

GC content: 58.53

Gene sequence:

>750_bases
ATGAGCCCGCATGACAAGAATACCTCTCCCATTGCCTCGGTCGTCGGCTCTTCGCTCGGCTTAAAGCGCACGGTGAAGGA
GGCGATCGGCGACAGGATCGAGGACTTGATCGCGTCCGGTATTCTCCAGCTTGGTGATGAACTCCCGAGCGAGCGCGAAC
TGGCCAAAATGCTTTCCGTCAGCCGGGAGACCGTGCGCGGCGCCATTCAGACCCTCTCCGCACGCGGCATTGTCTCGGTT
TCACAAGGGGCACGGACGCGTGTCGCCAATGTTTCGGTGGCGCAGCGGCGCGGTGGTCTTTCCACGCTCGGCACGATCGA
CACCTACGATCTCGAAACGGTTCACGCGTCGAGGCTGCTCGTCGAACGAGCCGTTGTAGCGGATGCGGCGCGGCATATTT
CCGCGCAGACGCTCGCCTTTCTCGATGCATCGCTTGTGGCCCAGCATGAGGTGCTCGACGATCCCATGCGCTTTCTGATC
TATGACCGAGAATTCCATCTCGCCATCTACCATTCCGCAAGCAATCCGTTACTCGCGGATTTCGTGACCGATCTTTACAC
CTATATGCTCGACCGGCGCCGTGTAGCAATGTCGAAACCAGACGCCATGAACCAGAGCTACGAGGATCATGCCGCGATCG
TCGAGGCCTTGAGGTCCCACGACCCAGAAGCCACGAGCCTGGTTTTCGATCGTCACATTAATCGTATTTATGCGACCAGC
AAAAAGCTCATGGGAAGCGGGTCGCAATAG

Upstream 100 bases:

>100_bases
TTAAAGATTATTCCTTGCCGATTGTGCCTTGCGAATTGTGCCTTGACGGTCAGATTATTTGAGCTTACTGGTCTGCTGGT
TGGTCCAGCAGGTCAGTCAA

Downstream 100 bases:

>100_bases
AACACGCCAGCCGCGCCTACAGCGGCGGAAAGATATGTCGCTCGTGAACACACGAGGCCGTGAAAACAAAACGCGTGAAC
AAGAGCGCGTTTAGGGGAGG

Product: regulatory protein GntR HTH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSPHDKNTSPIASVVGSSLGLKRTVKEAIGDRIEDLIASGILQLGDELPSERELAKMLSVSRETVRGAIQTLSARGIVSV
SQGARTRVANVSVAQRRGGLSTLGTIDTYDLETVHASRLLVERAVVADAARHISAQTLAFLDASLVAQHEVLDDPMRFLI
YDREFHLAIYHSASNPLLADFVTDLYTYMLDRRRVAMSKPDAMNQSYEDHAAIVEALRSHDPEATSLVFDRHINRIYATS
KKLMGSGSQ

Sequences:

>Translated_249_residues
MSPHDKNTSPIASVVGSSLGLKRTVKEAIGDRIEDLIASGILQLGDELPSERELAKMLSVSRETVRGAIQTLSARGIVSV
SQGARTRVANVSVAQRRGGLSTLGTIDTYDLETVHASRLLVERAVVADAARHISAQTLAFLDASLVAQHEVLDDPMRFLI
YDREFHLAIYHSASNPLLADFVTDLYTYMLDRRRVAMSKPDAMNQSYEDHAAIVEALRSHDPEATSLVFDRHINRIYATS
KKLMGSGSQ
>Mature_248_residues
SPHDKNTSPIASVVGSSLGLKRTVKEAIGDRIEDLIASGILQLGDELPSERELAKMLSVSRETVRGAIQTLSARGIVSVS
QGARTRVANVSVAQRRGGLSTLGTIDTYDLETVHASRLLVERAVVADAARHISAQTLAFLDASLVAQHEVLDDPMRFLIY
DREFHLAIYHSASNPLLADFVTDLYTYMLDRRRVAMSKPDAMNQSYEDHAAIVEALRSHDPEATSLVFDRHINRIYATSK
KLMGSGSQ

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=253, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789353, Length=214, Percent_Identity=28.9719626168224, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27285; Mature: 27154

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPHDKNTSPIASVVGSSLGLKRTVKEAIGDRIEDLIASGILQLGDELPSERELAKMLSV
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SRETVRGAIQTLSARGIVSVSQGARTRVANVSVAQRRGGLSTLGTIDTYDLETVHASRLL
HHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
VERAVVADAARHISAQTLAFLDASLVAQHEVLDDPMRFLIYDREFHLAIYHSASNPLLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEEECCCCCHHHH
FVTDLYTYMLDRRRVAMSKPDAMNQSYEDHAAIVEALRSHDPEATSLVFDRHINRIYATS
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KKLMGSGSQ
HHHHCCCCC
>Mature Secondary Structure 
SPHDKNTSPIASVVGSSLGLKRTVKEAIGDRIEDLIASGILQLGDELPSERELAKMLSV
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SRETVRGAIQTLSARGIVSVSQGARTRVANVSVAQRRGGLSTLGTIDTYDLETVHASRLL
HHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
VERAVVADAARHISAQTLAFLDASLVAQHEVLDDPMRFLIYDREFHLAIYHSASNPLLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEEEECCCCCHHHH
FVTDLYTYMLDRRRVAMSKPDAMNQSYEDHAAIVEALRSHDPEATSLVFDRHINRIYATS
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KKLMGSGSQ
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA