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The map label for this gene is ssb [H]

Identifier: 182679033

GI number: 182679033

Start: 2366006

End: 2366548

Strand: Reverse

Name: ssb [H]

Synonym: Bind_2069

Alternate gene names: 182679033

Gene position: 2366548-2366006 (Counterclockwise)

Preceding gene: 182679034

Following gene: 182679031

Centisome position: 56.75

GC content: 58.38

Gene sequence:

>543_bases
ATGTCGGGAAGTGTCAATAAGGTCATTCTCATCGGCAATCTCGGCCGGGACCCCGAGGTGCGGCGGATGAATTCCGGAGA
GGCGGTCGTCAGTTTCAGCCTGGCGACGACGGAATCCTGGCGCGATAAGATGTCGGGTGAGCGCCGGGACCGGACGGAAT
GGCACAATGTTGTGATTTTCAACGAGAATCTAGGCAAGATCGCAGAGCAATATTGCAAGAAGGGCTCAAAGGTCTATCTC
GAAGGCCAATTGCAGACGCGTGAATACCAAGATCGTGACGGCAACCAGCGCCGCACCACGGAAGTCGTCTTGCAGCGCTT
TCGCGGCGAATTGACCCTGCTCGATAGCCGTGGCGGCGGGCGTGGCGATTATGGCGGTGACGCTATGGTCGAAGGCGGCG
GCAATGCCAGTTTCGGGCGCAGCTCGCCCATGGAACGTTCGCAGGATCGCCCGATGGACCGGAATGAGGACAGAATGTCC
GATCGCCGCTCGAGTGGTCCGGGCCGCATGGCCGATGTCATTGATGATGATATTCCATTCTAA

Upstream 100 bases:

>100_bases
CGATTTAAACGCTTGCCAGCATGCAACCGCGCCGTTTCCTGTTATCACAGGCATTGAAGCATTATTTTAAACGCAATGCT
GCTCAGGATAGGAGGCGGTG

Downstream 100 bases:

>100_bases
GAGAGTGTGTGATCAAACTCCAAAATGGATTCACTTTGGAGTTTGATCTGAATACAATATACAATACTCAAGGGGCTTGT
TCCAAGCGCTCGACCATGGC

Product: single-strand binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSGSVNKVILIGNLGRDPEVRRMNSGEAVVSFSLATTESWRDKMSGERRDRTEWHNVVIFNENLGKIAEQYCKKGSKVYL
EGQLQTREYQDRDGNQRRTTEVVLQRFRGELTLLDSRGGGRGDYGGDAMVEGGGNASFGRSSPMERSQDRPMDRNEDRMS
DRRSSGPGRMADVIDDDIPF

Sequences:

>Translated_180_residues
MSGSVNKVILIGNLGRDPEVRRMNSGEAVVSFSLATTESWRDKMSGERRDRTEWHNVVIFNENLGKIAEQYCKKGSKVYL
EGQLQTREYQDRDGNQRRTTEVVLQRFRGELTLLDSRGGGRGDYGGDAMVEGGGNASFGRSSPMERSQDRPMDRNEDRMS
DRRSSGPGRMADVIDDDIPF
>Mature_179_residues
SGSVNKVILIGNLGRDPEVRRMNSGEAVVSFSLATTESWRDKMSGERRDRTEWHNVVIFNENLGKIAEQYCKKGSKVYLE
GQLQTREYQDRDGNQRRTTEVVLQRFRGELTLLDSRGGGRGDYGGDAMVEGGGNASFGRSSPMERSQDRPMDRNEDRMSD
RRSSGPGRMADVIDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=105, Percent_Identity=39.0476190476191, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1790494, Length=195, Percent_Identity=40.5128205128205, Blast_Score=133, Evalue=7e-33,
Organism=Drosophila melanogaster, GI85725234, Length=100, Percent_Identity=35, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647376, Length=100, Percent_Identity=35, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 20272; Mature: 20141

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSVNKVILIGNLGRDPEVRRMNSGEAVVSFSLATTESWRDKMSGERRDRTEWHNVVIF
CCCCCCEEEEEECCCCCCHHEECCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCEEEEE
NENLGKIAEQYCKKGSKVYLEGQLQTREYQDRDGNQRRTTEVVLQRFRGELTLLDSRGGG
ECCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC
RGDYGGDAMVEGGGNASFGRSSPMERSQDRPMDRNEDRMSDRRSSGPGRMADVIDDDIPF
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure 
SGSVNKVILIGNLGRDPEVRRMNSGEAVVSFSLATTESWRDKMSGERRDRTEWHNVVIF
CCCCCEEEEEECCCCCCHHEECCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCEEEEE
NENLGKIAEQYCKKGSKVYLEGQLQTREYQDRDGNQRRTTEVVLQRFRGELTLLDSRGGG
ECCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCC
RGDYGGDAMVEGGGNASFGRSSPMERSQDRPMDRNEDRMSDRRSSGPGRMADVIDDDIPF
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]