Click here to switch to the map view.

The map label for this gene is glcB [H]

Identifier: 182678852

GI number: 182678852

Start: 2149773

End: 2151725

Strand: Reverse

Name: glcB [H]

Synonym: Bind_1885

Alternate gene names: 182678852

Gene position: 2151725-2149773 (Counterclockwise)

Preceding gene: 182678853

Following gene: 182678846

Centisome position: 51.6

GC content: 58.22

Gene sequence:

>1953_bases
ATGCCACCCATCAAGATCGGCAGCTTGACCATTAATGAGTCTCTGCATGATTTCGTCACTTATGAAGCCTTGTCGGGCAC
GGGCATTGGCGCGCTGCAATTCTGGACTGGCCTGACCAAGCTGATCGACGAGTTTTCCCCGCTTTTGCGCGCGGCGGATG
CGGAGGGGGAGGGAACATCCGCCACGACTGAAGCTCCTTCTGCGGAGACTCTTGATCCGATCGCGGCCCGGCTCCTGGGT
CCGCAAATCGTCGTGCCGGCATCAGAGCCCCGTTATATCCTCAATGCCGCCAATGCGCGCTGGAGCAGCCTTTATGACGC
GCTTTATAGCTCGCACTTGATCTCCGAGGCCGATGGTGCGGAACGCGGGACGAGTTACAATAAGGTGCGCGGCGCCAAGG
TCATCGAAACGGTGTGCGCCTTTCTCGATGAGATTGTGCCTTTGGCAAACGGAAGCCATGGCGACGTCAAGCTCTATGGC
GTGGCCGGGGGAAAATTCTTCGCCGAATTTGCGCCGGGCGAGCGCGCGGAACTGAAAAATCCGGAGCAATATAGTGGCTT
TCAGGGACGCGCGGAGCGTCCTACGGCGCTTCTGCTTCGTCATGAAGAAGGGTATCTCGTTCTGCGGATCGATCGTCGTC
ATCCGATTGGACGTGAGCATCCGGCTGGTCTCGCCGATCTCCAGCTTGAATCTCTCTTGGCTGTCGTGATCGATTTCGAA
GACAGCGTTCTGTGTGTCGACGCCAAGGAGAAGGTTGCGGCCTATCGCAACTGGCTTGGTGTCTTGAAAGGAAGTTTGCG
GACTCAGTTCAAGAAAAACAACAAAGTGACAGAACGTCTGCTGGCTACGGATGCGTCCTTTACAGGTCCTAAGAGTGAGG
CTTTGTCCATGCCGGGGCATAGCCTCTTGATGGCAAGCCATGCGGCGCCAACCGTTCTCAGCGATCTGATCCTGGATAAA
CATGGCGAGCCGGTGCCGGAAACCCTGATCGATGCGGCTGTCACGGCGTTGATCGCGATCCAGGATCTGAAGCGTGGGCG
CGGGCTGCCAAATAGCGCGAAGGGCGCGATCTATGCCGTCAAGACAAAGCTGCGCGGCAGCCGCGATGTGCAAATCGCCT
GCGATATTTCCAGCCGATTGGAAGGCTTTTTGAGATTGCCGAAAGAGGCGATCAAGCTCGTCCTCATGGAGGAGACGGGA
GCGGTTCATGGGGCTCTTGCCGCGTGCAAGGCCGCAGCGCAAAATCGTTTCGTTGCCTTCATTCCCGATCCTGTCGATGC
GGCTGCTGAAGCCCTTCGCTTGAAAAGCGCCTCGGCGGCGCTCTCTTTCGCGCCGCCTGTATCCACGGCCTGCGCTTTCG
CGGCTTCGCCGAGCACAGTCGCGCTCCATGCCTTTGCCGTTCATCGCGGACAGGCGCCTTCAGCGCCCGTGTGGCCAGAG
CCTGTTGTCTTGGACAAGAAGAGTGGGGCAGAGACGGATCTCCAGACTCTTTGCAGCCAGATCCTGCTCATGCTGGTCGC
CTTGATTGAGTACGGCCAGAGCAGCTTGAAGCGGCATGAAGAGGATGGGCTGGATTTTGTCCGCATCGCTGATCGCGCCA
GCTTGCGCCTGATCAGTGCGCAGATTGCTAATTGGCTCCGCCAGGGGCTTTATGGCGAGGAACAGATCCGTGCTGCTTTG
CGGCAGGCTGCTGTTTCCCTCATGGAGAAGAATGCCAGTGATGCATCTTTCCAGGCACTTGCCGCAGAAGGCGCTGGATC
ATTGCTTCAAGCGGCATGGGATCTCATCGACCTTGGCGTGCAAACGCCAGATGCGCCGATCGAACCTGTCTTGCTGGCTT
ATCGGCGGGCAGCCAAAGAGCGACAAGGCACGACGGTACAGAATCCTTTTGAATCGATGAAAGGGGCGACGCGCGGGCTT
GAAAGCGGCGAAGCCTTCCGGACCAATGATTGA

Upstream 100 bases:

>100_bases
ACAGGCTGGACCATCGGACTTAAGAGTTTATGGAGTCTCTCTTCCGCGTTTTGTCCGCGATCAATGAAGAGAAGTTCTTG
GCTGCGAGGAAAAGCATAGA

Downstream 100 bases:

>100_bases
AATCGAACGGCGCTTGGTTGTCCGCTGATCATGCCGAGAGGCGGGACTGCGGAAGGACCAGCCGTTTCGCGGGAAAGGTG
ACGATGGCGCAAGTGCCGAT

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MPPIKIGSLTINESLHDFVTYEALSGTGIGALQFWTGLTKLIDEFSPLLRAADAEGEGTSATTEAPSAETLDPIAARLLG
PQIVVPASEPRYILNAANARWSSLYDALYSSHLISEADGAERGTSYNKVRGAKVIETVCAFLDEIVPLANGSHGDVKLYG
VAGGKFFAEFAPGERAELKNPEQYSGFQGRAERPTALLLRHEEGYLVLRIDRRHPIGREHPAGLADLQLESLLAVVIDFE
DSVLCVDAKEKVAAYRNWLGVLKGSLRTQFKKNNKVTERLLATDASFTGPKSEALSMPGHSLLMASHAAPTVLSDLILDK
HGEPVPETLIDAAVTALIAIQDLKRGRGLPNSAKGAIYAVKTKLRGSRDVQIACDISSRLEGFLRLPKEAIKLVLMEETG
AVHGALAACKAAAQNRFVAFIPDPVDAAAEALRLKSASAALSFAPPVSTACAFAASPSTVALHAFAVHRGQAPSAPVWPE
PVVLDKKSGAETDLQTLCSQILLMLVALIEYGQSSLKRHEEDGLDFVRIADRASLRLISAQIANWLRQGLYGEEQIRAAL
RQAAVSLMEKNASDASFQALAAEGAGSLLQAAWDLIDLGVQTPDAPIEPVLLAYRRAAKERQGTTVQNPFESMKGATRGL
ESGEAFRTND

Sequences:

>Translated_650_residues
MPPIKIGSLTINESLHDFVTYEALSGTGIGALQFWTGLTKLIDEFSPLLRAADAEGEGTSATTEAPSAETLDPIAARLLG
PQIVVPASEPRYILNAANARWSSLYDALYSSHLISEADGAERGTSYNKVRGAKVIETVCAFLDEIVPLANGSHGDVKLYG
VAGGKFFAEFAPGERAELKNPEQYSGFQGRAERPTALLLRHEEGYLVLRIDRRHPIGREHPAGLADLQLESLLAVVIDFE
DSVLCVDAKEKVAAYRNWLGVLKGSLRTQFKKNNKVTERLLATDASFTGPKSEALSMPGHSLLMASHAAPTVLSDLILDK
HGEPVPETLIDAAVTALIAIQDLKRGRGLPNSAKGAIYAVKTKLRGSRDVQIACDISSRLEGFLRLPKEAIKLVLMEETG
AVHGALAACKAAAQNRFVAFIPDPVDAAAEALRLKSASAALSFAPPVSTACAFAASPSTVALHAFAVHRGQAPSAPVWPE
PVVLDKKSGAETDLQTLCSQILLMLVALIEYGQSSLKRHEEDGLDFVRIADRASLRLISAQIANWLRQGLYGEEQIRAAL
RQAAVSLMEKNASDASFQALAAEGAGSLLQAAWDLIDLGVQTPDAPIEPVLLAYRRAAKERQGTTVQNPFESMKGATRGL
ESGEAFRTND
>Mature_649_residues
PPIKIGSLTINESLHDFVTYEALSGTGIGALQFWTGLTKLIDEFSPLLRAADAEGEGTSATTEAPSAETLDPIAARLLGP
QIVVPASEPRYILNAANARWSSLYDALYSSHLISEADGAERGTSYNKVRGAKVIETVCAFLDEIVPLANGSHGDVKLYGV
AGGKFFAEFAPGERAELKNPEQYSGFQGRAERPTALLLRHEEGYLVLRIDRRHPIGREHPAGLADLQLESLLAVVIDFED
SVLCVDAKEKVAAYRNWLGVLKGSLRTQFKKNNKVTERLLATDASFTGPKSEALSMPGHSLLMASHAAPTVLSDLILDKH
GEPVPETLIDAAVTALIAIQDLKRGRGLPNSAKGAIYAVKTKLRGSRDVQIACDISSRLEGFLRLPKEAIKLVLMEETGA
VHGALAACKAAAQNRFVAFIPDPVDAAAEALRLKSASAALSFAPPVSTACAFAASPSTVALHAFAVHRGQAPSAPVWPEP
VVLDKKSGAETDLQTLCSQILLMLVALIEYGQSSLKRHEEDGLDFVRIADRASLRLISAQIANWLRQGLYGEEQIRAALR
QAAVSLMEKNASDASFQALAAEGAGSLLQAAWDLIDLGVQTPDAPIEPVLLAYRRAAKERQGTTVQNPFESMKGATRGLE
SGEAFRTND

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=720, Percent_Identity=30.6944444444444, Blast_Score=292, Evalue=4e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 69620; Mature: 69489

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPIKIGSLTINESLHDFVTYEALSGTGIGALQFWTGLTKLIDEFSPLLRAADAEGEGTS
CCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ATTEAPSAETLDPIAARLLGPQIVVPASEPRYILNAANARWSSLYDALYSSHLISEADGA
CCCCCCCCCHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
ERGTSYNKVRGAKVIETVCAFLDEIVPLANGSHGDVKLYGVAGGKFFAEFAPGERAELKN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCCCCCCC
PEQYSGFQGRAERPTALLLRHEEGYLVLRIDRRHPIGREHPAGLADLQLESLLAVVIDFE
CHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEECC
DSVLCVDAKEKVAAYRNWLGVLKGSLRTQFKKNNKVTERLLATDASFTGPKSEALSMPGH
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHCCCCC
SLLMASHAAPTVLSDLILDKHGEPVPETLIDAAVTALIAIQDLKRGRGLPNSAKGAIYAV
HHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
KTKLRGSRDVQIACDISSRLEGFLRLPKEAIKLVLMEETGAVHGALAACKAAAQNRFVAF
EECCCCCCCEEEEECHHHHHHHHHHCCHHHHHEEEECCCCCHHHHHHHHHHHHCCCEEEE
IPDPVDAAAEALRLKSASAALSFAPPVSTACAFAASPSTVALHAFAVHRGQAPSAPVWPE
CCCCHHHHHHHHHHHHHHCCEECCCCHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCC
PVVLDKKSGAETDLQTLCSQILLMLVALIEYGQSSLKRHEEDGLDFVRIADRASLRLISA
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEHHHHHHHHHHH
QIANWLRQGLYGEEQIRAALRQAAVSLMEKNASDASFQALAAEGAGSLLQAAWDLIDLGV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
QTPDAPIEPVLLAYRRAAKERQGTTVQNPFESMKGATRGLESGEAFRTND
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PPIKIGSLTINESLHDFVTYEALSGTGIGALQFWTGLTKLIDEFSPLLRAADAEGEGTS
CCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ATTEAPSAETLDPIAARLLGPQIVVPASEPRYILNAANARWSSLYDALYSSHLISEADGA
CCCCCCCCCHHHHHHHHHCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
ERGTSYNKVRGAKVIETVCAFLDEIVPLANGSHGDVKLYGVAGGKFFAEFAPGERAELKN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCCCCCCC
PEQYSGFQGRAERPTALLLRHEEGYLVLRIDRRHPIGREHPAGLADLQLESLLAVVIDFE
CHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEEECC
DSVLCVDAKEKVAAYRNWLGVLKGSLRTQFKKNNKVTERLLATDASFTGPKSEALSMPGH
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHCCCCC
SLLMASHAAPTVLSDLILDKHGEPVPETLIDAAVTALIAIQDLKRGRGLPNSAKGAIYAV
HHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
KTKLRGSRDVQIACDISSRLEGFLRLPKEAIKLVLMEETGAVHGALAACKAAAQNRFVAF
EECCCCCCCEEEEECHHHHHHHHHHCCHHHHHEEEECCCCCHHHHHHHHHHHHCCCEEEE
IPDPVDAAAEALRLKSASAALSFAPPVSTACAFAASPSTVALHAFAVHRGQAPSAPVWPE
CCCCHHHHHHHHHHHHHHCCEECCCCHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCC
PVVLDKKSGAETDLQTLCSQILLMLVALIEYGQSSLKRHEEDGLDFVRIADRASLRLISA
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEHHHHHHHHHHH
QIANWLRQGLYGEEQIRAALRQAAVSLMEKNASDASFQALAAEGAGSLLQAAWDLIDLGV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
QTPDAPIEPVLLAYRRAAKERQGTTVQNPFESMKGATRGLESGEAFRTND
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA