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The map label for this gene is aroC

Identifier: 182678835

GI number: 182678835

Start: 2128559

End: 2129680

Strand: Reverse

Name: aroC

Synonym: Bind_1868

Alternate gene names: 182678835

Gene position: 2129680-2128559 (Counterclockwise)

Preceding gene: 182678836

Following gene: 182678830

Centisome position: 51.07

GC content: 60.34

Gene sequence:

>1122_bases
ATGTCTCACAATACATTCGGCCATCTCTTTCGCGTGACGACCTTTGGGGAAAGCCATGGACCGGCCATTGGCTGCGTGGT
GGATGGTTGCCCTCCCTTGATCCCAATCGATGAAGCCGACATCCAGACCTTTCTCGATCTGCGCCGTCCCGGCACGTCGC
GTTTCACGACACAGCGCCAGGAAGCCGATCGTGTGCGTATCCTCTCGGGTGTCTTCACGGACGAGGCGAGCGGCAAACAG
GTTTCGACGGGCACACCGATCGCGCTCCTGATCGAAAATACGGATCAGCGCTCGAAGGATTATGACGCGATCAAAAATCT
CTATCGACCAGGCCATGCCGATTTCGCCTATGACGCAAAATATGGCTTGCGTGATCATCGTGGCGGGGGCCGTTCCTCGG
CGCGCGAAACCGCGACGCGGGTCGCAGCCGGTGCCATCGCCCGCAAGGTGGTCGCGGATGTGACGATCAGAGGGGCCCTC
GTGCAGATGGGGCCGCATAAGATCAACCGCGACGCGTGGGATTGGGACGAGACGACGCGCAATCCCTTCTTCTGCCCGGA
TGCAAAGGCGGCGGCTTTTTTTGAAACTTATCTCGATGATATACGCAAGGCCGGGTCCTCGATTGGCGCGGTCATTGAGA
TCGTCGCGGAGAATGTGCCGGCCGGCTGGGGCGCTCCGCTTTATGGCAAGCTCGACGCTGATCTTGCTTCCGGCTTGATG
TCGATCAATGCGGTGAAAGGTGTCGAAATCGGCGAGGGTTTTGACGCGGCCGCGCTGAGCGGTGAAGCCAATGCCGATGA
AATGCGGATCGGTTCTCTCGGCGAGCCGGTCTTTCTCTCGAACCATGCGGGCGGCATTCTGGGGGGTATTTCGACGGGCC
AGCCGCTCGTCATGCGCTTTGCTGTCAAACCGACCTCTTCGATCCTGCAACCGCGTCATACGATCGACCGTTCAGGCCAT
GAAAGCGAGATCGTCACTAAGGGGCGTCATGATCCGTGTGTCGGCATACGCGCCGTGCCGGTGGGCGAGGCCATGGTCGC
TTGCGTGCTCGCCGATCATTTTCTGCGCCATCGCGGCCAGATCGGTGAAGGCGCTGTCTGGCCGGCGAACCGATCACGCT
GA

Upstream 100 bases:

>100_bases
ACGCGATTGGAACAAGGAAAAGGGCCGGCTGCTGCGCGACAAACATTGAGATCGGCCTTCCTCATCTTCTTTGTCTTCCC
TGTTTTCGGCATCATCTCTC

Downstream 100 bases:

>100_bases
AATCTCCCCCGGCTTTTATTGCTGAGGTACGCTGCCGTCGATTTCGGTCGAATAGCTTGCAAGAGCATCGGCCGTATCCC
GCATTGGTTGCTGACTTACG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MSHNTFGHLFRVTTFGESHGPAIGCVVDGCPPLIPIDEADIQTFLDLRRPGTSRFTTQRQEADRVRILSGVFTDEASGKQ
VSTGTPIALLIENTDQRSKDYDAIKNLYRPGHADFAYDAKYGLRDHRGGGRSSARETATRVAAGAIARKVVADVTIRGAL
VQMGPHKINRDAWDWDETTRNPFFCPDAKAAAFFETYLDDIRKAGSSIGAVIEIVAENVPAGWGAPLYGKLDADLASGLM
SINAVKGVEIGEGFDAAALSGEANADEMRIGSLGEPVFLSNHAGGILGGISTGQPLVMRFAVKPTSSILQPRHTIDRSGH
ESEIVTKGRHDPCVGIRAVPVGEAMVACVLADHFLRHRGQIGEGAVWPANRSR

Sequences:

>Translated_373_residues
MSHNTFGHLFRVTTFGESHGPAIGCVVDGCPPLIPIDEADIQTFLDLRRPGTSRFTTQRQEADRVRILSGVFTDEASGKQ
VSTGTPIALLIENTDQRSKDYDAIKNLYRPGHADFAYDAKYGLRDHRGGGRSSARETATRVAAGAIARKVVADVTIRGAL
VQMGPHKINRDAWDWDETTRNPFFCPDAKAAAFFETYLDDIRKAGSSIGAVIEIVAENVPAGWGAPLYGKLDADLASGLM
SINAVKGVEIGEGFDAAALSGEANADEMRIGSLGEPVFLSNHAGGILGGISTGQPLVMRFAVKPTSSILQPRHTIDRSGH
ESEIVTKGRHDPCVGIRAVPVGEAMVACVLADHFLRHRGQIGEGAVWPANRSR
>Mature_372_residues
SHNTFGHLFRVTTFGESHGPAIGCVVDGCPPLIPIDEADIQTFLDLRRPGTSRFTTQRQEADRVRILSGVFTDEASGKQV
STGTPIALLIENTDQRSKDYDAIKNLYRPGHADFAYDAKYGLRDHRGGGRSSARETATRVAAGAIARKVVADVTIRGALV
QMGPHKINRDAWDWDETTRNPFFCPDAKAAAFFETYLDDIRKAGSSIGAVIEIVAENVPAGWGAPLYGKLDADLASGLMS
INAVKGVEIGEGFDAAALSGEANADEMRIGSLGEPVFLSNHAGGILGGISTGQPLVMRFAVKPTSSILQPRHTIDRSGHE
SEIVTKGRHDPCVGIRAVPVGEAMVACVLADHFLRHRGQIGEGAVWPANRSR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=363, Percent_Identity=61.1570247933884, Blast_Score=415, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=42.8954423592493, Blast_Score=281, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BEII9 (B2IDQ8)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001832981.1
- ProteinModelPortal:   B2IDQ8
- GeneID:   6198852
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1868
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39995; Mature: 39863

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTFGESHGPAIGCVVDGCPPLIPIDEADIQTFLDLRRPGTSRFTTQRQ
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
EADRVRILSGVFTDEASGKQVSTGTPIALLIENTDQRSKDYDAIKNLYRPGHADFAYDAK
HHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCC
YGLRDHRGGGRSSARETATRVAAGAIARKVVADVTIRGALVQMGPHKINRDAWDWDETTR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
NPFFCPDAKAAAFFETYLDDIRKAGSSIGAVIEIVAENVPAGWGAPLYGKLDADLASGLM
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
SINAVKGVEIGEGFDAAALSGEANADEMRIGSLGEPVFLSNHAGGILGGISTGQPLVMRF
HHHHCCCCCCCCCCCHHHCCCCCCCCCEEECCCCCCEEEECCCCCEEECCCCCCCEEEEE
AVKPTSSILQPRHTIDRSGHESEIVTKGRHDPCVGIRAVPVGEAMVACVLADHFLRHRGQ
EECCHHHHHCCHHHHCCCCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCC
IGEGAVWPANRSR
CCCCCCCCCCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTFGESHGPAIGCVVDGCPPLIPIDEADIQTFLDLRRPGTSRFTTQRQ
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
EADRVRILSGVFTDEASGKQVSTGTPIALLIENTDQRSKDYDAIKNLYRPGHADFAYDAK
HHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCC
YGLRDHRGGGRSSARETATRVAAGAIARKVVADVTIRGALVQMGPHKINRDAWDWDETTR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
NPFFCPDAKAAAFFETYLDDIRKAGSSIGAVIEIVAENVPAGWGAPLYGKLDADLASGLM
CCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
SINAVKGVEIGEGFDAAALSGEANADEMRIGSLGEPVFLSNHAGGILGGISTGQPLVMRF
HHHHCCCCCCCCCCCHHHCCCCCCCCCEEECCCCCCEEEECCCCCEEECCCCCCCEEEEE
AVKPTSSILQPRHTIDRSGHESEIVTKGRHDPCVGIRAVPVGEAMVACVLADHFLRHRGQ
EECCHHHHHCCHHHHCCCCCCCHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCC
IGEGAVWPANRSR
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA