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The map label for this gene is ybaL [H]

Identifier: 182678825

GI number: 182678825

Start: 2117674

End: 2119515

Strand: Reverse

Name: ybaL [H]

Synonym: Bind_1858

Alternate gene names: 182678825

Gene position: 2119515-2117674 (Counterclockwise)

Preceding gene: 182678826

Following gene: 182678810

Centisome position: 50.83

GC content: 57.71

Gene sequence:

>1842_bases
ATGCCGCATGGAAACCCCTTGATTTCCACGATCGTCACGGCGTTCGTTCTGGCCTTTCTCCTGGGCGTTTTGGCCAATCG
GTTTCGCCTGCCGCCGCTCGTTGGCTATCTCGTCGCCGGCATCATCGTTGGCCCGCATACGCCTGGCCTCGTCGCGGATC
AGACGCTTGCGCAGGAACTCGCAGAAATCGGCATCATCCTCCTGATGTTCGGTGTCGGCCTGCATTTCTCGCTGAAGGAT
CTTGCTTCCGTTCGCGCTGTCGCCGTGCCAGGTGCGATCGCTCAGATCCTCTGCGCCACTTTACTGGGTGTCGGCTTGGG
ACAATGGATGGGCTGGCCGCTCGGCGGCAGTCTGATCTTTGGTCTCGCTCTTTCGGTCGCCTCGACGGTCGTGCTGCTCA
AGGCGCTGCAGGATCGCCGCCTCCTCACGACCGAGCGCGGCAAGATCGCGGTCGGATGGCTCATCGTCGAGGATCTTATC
AGTGTCCTCGCTTTGGTTCTCATCCCGGCGATTGCCGATATTCTGCATGGCAGCGATGGCGCGAAAGAGCCGCTGGCAGC
CGGTTTCGATCAACTGCTCGGCATCGATCTGGGGATCGCGGGCCTGATCGTCGCAATAGTTCTTAAAATTTCTGTCTTTC
TCGCGCTCATGCTGATCGCCGGCCGGCGTGTCATTCCCTGGTGCTTGCACTGGATTGCCCATACGGGTTCACGCGAATTG
TTCCGCCTTGGCGTGCTGGCGATCGCACTCGGTGTCGCTTTTGGCGCAACCTCGCTGTTTGGTGTTTCCCTGTCTCTGAG
CGCCTTTTTTGCCGGCATGGTTTTGGCCGAAAGCGAACTCAGTCACCGTGCCGCTCAGGAAAGCCTGCCTTTGCGGGACG
CCTTTTCTGTTTTGTTTTTCGTGTCGGTCGGCATGCTGTTCGACCCATCGATCGTGCTCAAAGCCCCGCTGCCTCTGCTT
GCTACGGTGTTTATTATCCTGATCGGCAAATCGATCGCGGCCTTCTTTATCGTTCGTATTCTCGGCGGGACGATCGGCGC
TGCTTTGACCATCTCGGCGAGCCTCGCCCAGATTGGCGAATTTTCCTTCATTCTCGCTGAACTCGGTATTGCTCTCGATT
TTCTCCCCGTCGAGGGGCGGGCCTTGATCCTCGCCGGATCGATCTTGTCGATCATTCTCAATTCAGCCGTCTTTTCCCTT
GTCGATCTTCTAAAACCTCGCTTGGAAGCGAAAATCCAGCATCCCCTTCCACAAGACGCAACGCTACGCCTTGAAACCGC
TGTCATGGCGGAATCGGATGTGTCTTCAATGCAGGAAAGAGAGGAGGTGAAGAGGGACAGCATGATTGCGGCCAACGAGG
ATCGCATTGAGGCCGCGCGGGAGGTTGGAGAGGAAACAGATTACAAGCCGACCCGTTTGAAGGAGCATACGATCCTGATC
GGCTTCGGGCGGGTCGGCGCATTCATCGGTAAGACGCTTGAGACCGCGGGCGTTCCTTTCCTCGTTATTGAGGAGAATGA
TCAGATCATCGCTTTGCTTGAGGAACAGAATGTGGAGACCATAGCCGGTAATGCGGCGAGTGATAGCATTCTGGCGCTGG
CCAACCCCGGAACGGCACACAATCTGTTGATTGCCATCCCCAATGCCTTTGAGGCAGGGCAGGTCACGGTTCAGGCGCGG
CGGGCCAATCCCTCATTACGGATCATCGTCCGTGCTCATTCCGATGCGGAGGTCGATCATCTTGAAAAGCTGGGCGCTGA
TACGGTGATCATGGGCGAGCGGGAAATCGCGCGCGGTATGCTCCATTGCATGGGTTTGACCGGACCAGCGATCAGCGCGT
GA

Upstream 100 bases:

>100_bases
TAAAGACGACCTGGAGCTTTCCTCCCTCTTAAACCGTGCTATCAAACAAACCGCTTGTGTCGTCCTGACACAATGATCCA
AACCACTTTCCGGGAACGCC

Downstream 100 bases:

>100_bases
GTGATCAGGCCGCGCAGTGCAGAGCGTAGGAATAGTTGTGGCGACTGCGGGCGCTATGCGGGTCCATAATAACGTGGCTA
AGCGAACTAACGCTTAGAAA

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MPHGNPLISTIVTAFVLAFLLGVLANRFRLPPLVGYLVAGIIVGPHTPGLVADQTLAQELAEIGIILLMFGVGLHFSLKD
LASVRAVAVPGAIAQILCATLLGVGLGQWMGWPLGGSLIFGLALSVASTVVLLKALQDRRLLTTERGKIAVGWLIVEDLI
SVLALVLIPAIADILHGSDGAKEPLAAGFDQLLGIDLGIAGLIVAIVLKISVFLALMLIAGRRVIPWCLHWIAHTGSREL
FRLGVLAIALGVAFGATSLFGVSLSLSAFFAGMVLAESELSHRAAQESLPLRDAFSVLFFVSVGMLFDPSIVLKAPLPLL
ATVFIILIGKSIAAFFIVRILGGTIGAALTISASLAQIGEFSFILAELGIALDFLPVEGRALILAGSILSIILNSAVFSL
VDLLKPRLEAKIQHPLPQDATLRLETAVMAESDVSSMQEREEVKRDSMIAANEDRIEAAREVGEETDYKPTRLKEHTILI
GFGRVGAFIGKTLETAGVPFLVIEENDQIIALLEEQNVETIAGNAASDSILALANPGTAHNLLIAIPNAFEAGQVTVQAR
RANPSLRIIVRAHSDAEVDHLEKLGADTVIMGEREIARGMLHCMGLTGPAISA

Sequences:

>Translated_613_residues
MPHGNPLISTIVTAFVLAFLLGVLANRFRLPPLVGYLVAGIIVGPHTPGLVADQTLAQELAEIGIILLMFGVGLHFSLKD
LASVRAVAVPGAIAQILCATLLGVGLGQWMGWPLGGSLIFGLALSVASTVVLLKALQDRRLLTTERGKIAVGWLIVEDLI
SVLALVLIPAIADILHGSDGAKEPLAAGFDQLLGIDLGIAGLIVAIVLKISVFLALMLIAGRRVIPWCLHWIAHTGSREL
FRLGVLAIALGVAFGATSLFGVSLSLSAFFAGMVLAESELSHRAAQESLPLRDAFSVLFFVSVGMLFDPSIVLKAPLPLL
ATVFIILIGKSIAAFFIVRILGGTIGAALTISASLAQIGEFSFILAELGIALDFLPVEGRALILAGSILSIILNSAVFSL
VDLLKPRLEAKIQHPLPQDATLRLETAVMAESDVSSMQEREEVKRDSMIAANEDRIEAAREVGEETDYKPTRLKEHTILI
GFGRVGAFIGKTLETAGVPFLVIEENDQIIALLEEQNVETIAGNAASDSILALANPGTAHNLLIAIPNAFEAGQVTVQAR
RANPSLRIIVRAHSDAEVDHLEKLGADTVIMGEREIARGMLHCMGLTGPAISA
>Mature_612_residues
PHGNPLISTIVTAFVLAFLLGVLANRFRLPPLVGYLVAGIIVGPHTPGLVADQTLAQELAEIGIILLMFGVGLHFSLKDL
ASVRAVAVPGAIAQILCATLLGVGLGQWMGWPLGGSLIFGLALSVASTVVLLKALQDRRLLTTERGKIAVGWLIVEDLIS
VLALVLIPAIADILHGSDGAKEPLAAGFDQLLGIDLGIAGLIVAIVLKISVFLALMLIAGRRVIPWCLHWIAHTGSRELF
RLGVLAIALGVAFGATSLFGVSLSLSAFFAGMVLAESELSHRAAQESLPLRDAFSVLFFVSVGMLFDPSIVLKAPLPLLA
TVFIILIGKSIAAFFIVRILGGTIGAALTISASLAQIGEFSFILAELGIALDFLPVEGRALILAGSILSIILNSAVFSLV
DLLKPRLEAKIQHPLPQDATLRLETAVMAESDVSSMQEREEVKRDSMIAANEDRIEAAREVGEETDYKPTRLKEHTILIG
FGRVGAFIGKTLETAGVPFLVIEENDQIIALLEEQNVETIAGNAASDSILALANPGTAHNLLIAIPNAFEAGQVTVQARR
ANPSLRIIVRAHSDAEVDHLEKLGADTVIMGEREIARGMLHCMGLTGPAISA

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=374, Percent_Identity=25.1336898395722, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1786685, Length=604, Percent_Identity=50.4966887417219, Blast_Score=545, Evalue=1e-156,
Organism=Escherichia coli, GI1786232, Length=587, Percent_Identity=27.0868824531516, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1789749, Length=564, Percent_Identity=25, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 64787; Mature: 64656

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGNPLISTIVTAFVLAFLLGVLANRFRLPPLVGYLVAGIIVGPHTPGLVADQTLAQEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCHHHHHHHHH
AEIGIILLMFGVGLHFSLKDLASVRAVAVPGAIAQILCATLLGVGLGQWMGWPLGGSLIF
HHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GLALSVASTVVLLKALQDRRLLTTERGKIAVGWLIVEDLISVLALVLIPAIADILHGSDG
HHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AKEPLAAGFDQLLGIDLGIAGLIVAIVLKISVFLALMLIAGRRVIPWCLHWIAHTGSREL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
FRLGVLAIALGVAFGATSLFGVSLSLSAFFAGMVLAESELSHRAAQESLPLRDAFSVLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VSVGMLFDPSIVLKAPLPLLATVFIILIGKSIAAFFIVRILGGTIGAALTISASLAQIGE
HHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFILAELGIALDFLPVEGRALILAGSILSIILNSAVFSLVDLLKPRLEAKIQHPLPQDA
HHHHHHHHHHHHEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TLRLETAVMAESDVSSMQEREEVKRDSMIAANEDRIEAAREVGEETDYKPTRLKEHTILI
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEE
GFGRVGAFIGKTLETAGVPFLVIEENDQIIALLEEQNVETIAGNAASDSILALANPGTAH
EEHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHCCCCCCCCEEEEECCCCCC
NLLIAIPNAFEAGQVTVQARRANPSLRIIVRAHSDAEVDHLEKLGADTVIMGEREIARGM
EEEEEECCCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHCCCCEEEECCHHHHHHH
LHCMGLTGPAISA
HHHHCCCCCCCCC
>Mature Secondary Structure 
PHGNPLISTIVTAFVLAFLLGVLANRFRLPPLVGYLVAGIIVGPHTPGLVADQTLAQEL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCCHHHHHHHHH
AEIGIILLMFGVGLHFSLKDLASVRAVAVPGAIAQILCATLLGVGLGQWMGWPLGGSLIF
HHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GLALSVASTVVLLKALQDRRLLTTERGKIAVGWLIVEDLISVLALVLIPAIADILHGSDG
HHHHHHHHHHHHHHHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AKEPLAAGFDQLLGIDLGIAGLIVAIVLKISVFLALMLIAGRRVIPWCLHWIAHTGSREL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
FRLGVLAIALGVAFGATSLFGVSLSLSAFFAGMVLAESELSHRAAQESLPLRDAFSVLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VSVGMLFDPSIVLKAPLPLLATVFIILIGKSIAAFFIVRILGGTIGAALTISASLAQIGE
HHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFILAELGIALDFLPVEGRALILAGSILSIILNSAVFSLVDLLKPRLEAKIQHPLPQDA
HHHHHHHHHHHHEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TLRLETAVMAESDVSSMQEREEVKRDSMIAANEDRIEAAREVGEETDYKPTRLKEHTILI
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEE
GFGRVGAFIGKTLETAGVPFLVIEENDQIIALLEEQNVETIAGNAASDSILALANPGTAH
EEHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCHHHCCCCCCCCEEEEECCCCCC
NLLIAIPNAFEAGQVTVQARRANPSLRIIVRAHSDAEVDHLEKLGADTVIMGEREIARGM
EEEEEECCCCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHCCCCEEEECCHHHHHHH
LHCMGLTGPAISA
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]