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The map label for this gene is ydbM [H]

Identifier: 182678814

GI number: 182678814

Start: 2104084

End: 2105232

Strand: Direct

Name: ydbM [H]

Synonym: Bind_1847

Alternate gene names: 182678814

Gene position: 2104084-2105232 (Clockwise)

Preceding gene: 182678813

Following gene: 182678815

Centisome position: 50.46

GC content: 63.71

Gene sequence:

>1149_bases
ATGAACACGCATGTCACTGATCTGCCCTCTCTTCTCGGCACCGCACGAGTTCTCGCCGAAAGCTTCGCCGAGACGGCAGC
CCATTATGATGCCACAGGCGCCTTTCCGTTTGCGAATTTCCAGGCCCTGTTCGACTCCGGCCTTCTGACACTCACGGCGC
CAAAGGCCTATGGCGGGGCGGGCCGGGGGCTCGTCGATGCCCAGGCCGTCATCAGTGAGATCGCAAGGGGTGAGGCCTCG
ACGGGCCTGGTGCTCGCAATGAACTATTTCCAGAACGCCAATATGGCGCGACCCACACAATGGCCTTCCCATGTGGCGGC
AGCAGTGGTCAGACGCTCACTCGAAGAAGTGACGCTCCTGAACGCTGCTCAGGCAGAGCCGAATATTGGCTCGCCCTCTC
ATGGCGCCCTGCCCGAGACACGGGCGCGGCTTGTCGAGGGAACCTGGCGGATCACGGGCCGCAAGGCCTATGTGACGGGC
CAGCCCGGCCTTGCCTTCGCGGCCGTTTTCGCCGTGACCGAGGAAGATGATCCGCGTCTCTCTCATTTCCTCGTCCCGCT
CGACGCGCCCGGGATCAGAATCATCGAGACTTGGAACGCCACCGGCATGCGGGCGACAGCCAGCCATGACATCATTTTCG
ATAATGTCGCCGTTCCCCTTGATCATCGTCTCGATGATCAGCCTGCCGAGGGAGGCGTCAAGCGTGACGAGACGAGCATG
GCCTGGGCTTCGATCTTGATCGCTTCCGTCTATGACGGCATCGCGCGGTCGGCACGTGACTGGATCGTCGATTTCGTCAA
GAACCGCGTGCCCGGAAGTCTCGGCGCACCCTTGGCGAGCGTGCCGCGCATTCGCGACGCCATCGGCGACATCGAGGTGC
GTCTCATCACCAATGCCCGGCTCCTGCGCTCGGTGGCGGAAGATGTCGATGCCGGGCTGCCGCTCGGACCCGCGCCCGCC
AGCGTCAGACATGTCGTCATCGAAAACGCTTTCGCCGTGACGAGCCTCGCTCTCGAACTCGGTGGCAATCCCGGCGTCTC
GCGAGCCAATCCGCTGGAGCGTCATCATCGCAACGCCCTCACCGGGCGCGCCCATGCCCCCCAGGGCAATTTGATCCGCG
GCATTGCCGCCCGCGCCATTCTCGACTGA

Upstream 100 bases:

>100_bases
CTCGGTGATTACGCATACGGCCTATGATCGGGAAGAACACGCTTGATATCTGGAATACGTGCCCGGCGTGTATGTGGCCG
TTAGAACTCCAGGGAGCCTC

Downstream 100 bases:

>100_bases
TCGCCGCAGGAGGCTTCATGACAGATAGTGACACTTTCGACATAGAGGCGCTGAATGCGCTCCGCCTGCTTGGTCCCGAC
CCCGCCGATTGGGTCGCCGA

Product: acyl-CoA dehydrogenase type 2

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNTHVTDLPSLLGTARVLAESFAETAAHYDATGAFPFANFQALFDSGLLTLTAPKAYGGAGRGLVDAQAVISEIARGEAS
TGLVLAMNYFQNANMARPTQWPSHVAAAVVRRSLEEVTLLNAAQAEPNIGSPSHGALPETRARLVEGTWRITGRKAYVTG
QPGLAFAAVFAVTEEDDPRLSHFLVPLDAPGIRIIETWNATGMRATASHDIIFDNVAVPLDHRLDDQPAEGGVKRDETSM
AWASILIASVYDGIARSARDWIVDFVKNRVPGSLGAPLASVPRIRDAIGDIEVRLITNARLLRSVAEDVDAGLPLGPAPA
SVRHVVIENAFAVTSLALELGGNPGVSRANPLERHHRNALTGRAHAPQGNLIRGIAARAILD

Sequences:

>Translated_382_residues
MNTHVTDLPSLLGTARVLAESFAETAAHYDATGAFPFANFQALFDSGLLTLTAPKAYGGAGRGLVDAQAVISEIARGEAS
TGLVLAMNYFQNANMARPTQWPSHVAAAVVRRSLEEVTLLNAAQAEPNIGSPSHGALPETRARLVEGTWRITGRKAYVTG
QPGLAFAAVFAVTEEDDPRLSHFLVPLDAPGIRIIETWNATGMRATASHDIIFDNVAVPLDHRLDDQPAEGGVKRDETSM
AWASILIASVYDGIARSARDWIVDFVKNRVPGSLGAPLASVPRIRDAIGDIEVRLITNARLLRSVAEDVDAGLPLGPAPA
SVRHVVIENAFAVTSLALELGGNPGVSRANPLERHHRNALTGRAHAPQGNLIRGIAARAILD
>Mature_382_residues
MNTHVTDLPSLLGTARVLAESFAETAAHYDATGAFPFANFQALFDSGLLTLTAPKAYGGAGRGLVDAQAVISEIARGEAS
TGLVLAMNYFQNANMARPTQWPSHVAAAVVRRSLEEVTLLNAAQAEPNIGSPSHGALPETRARLVEGTWRITGRKAYVTG
QPGLAFAAVFAVTEEDDPRLSHFLVPLDAPGIRIIETWNATGMRATASHDIIFDNVAVPLDHRLDDQPAEGGVKRDETSM
AWASILIASVYDGIARSARDWIVDFVKNRVPGSLGAPLASVPRIRDAIGDIEVRLITNARLLRSVAEDVDAGLPLGPAPA
SVRHVVIENAFAVTSLALELGGNPGVSRANPLERHHRNALTGRAHAPQGNLIRGIAARAILD

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=360, Percent_Identity=28.8888888888889, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI4501859, Length=345, Percent_Identity=24.0579710144928, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557231, Length=383, Percent_Identity=25.3263707571802, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI187960098, Length=383, Percent_Identity=25.3263707571802, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786223, Length=387, Percent_Identity=23.5142118863049, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=339, Percent_Identity=23.3038348082596, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=22.6063829787234, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646207, Length=389, Percent_Identity=26.4781491002571, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 40543; Mature: 40543

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHVTDLPSLLGTARVLAESFAETAAHYDATGAFPFANFQALFDSGLLTLTAPKAYGGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCC
GRGLVDAQAVISEIARGEASTGLVLAMNYFQNANMARPTQWPSHVAAAVVRRSLEEVTLL
CCCHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NAAQAEPNIGSPSHGALPETRARLVEGTWRITGRKAYVTGQPGLAFAAVFAVTEEDDPRL
HHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEECEEEEEECCCCCEEEEEEEECCCCCCCC
SHFLVPLDAPGIRIIETWNATGMRATASHDIIFDNVAVPLDHRLDDQPAEGGVKRDETSM
EEEEEECCCCCEEEEEECCCCCCEECCCCCEEECCEECCCCCCCCCCCCCCCCCCCHHHH
AWASILIASVYDGIARSARDWIVDFVKNRVPGSLGAPLASVPRIRDAIGDIEVRLITNAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCHH
LLRSVAEDVDAGLPLGPAPASVRHVVIENAFAVTSLALELGGNPGVSRANPLERHHRNAL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
TGRAHAPQGNLIRGIAARAILD
CCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNTHVTDLPSLLGTARVLAESFAETAAHYDATGAFPFANFQALFDSGLLTLTAPKAYGGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCC
GRGLVDAQAVISEIARGEASTGLVLAMNYFQNANMARPTQWPSHVAAAVVRRSLEEVTLL
CCCHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NAAQAEPNIGSPSHGALPETRARLVEGTWRITGRKAYVTGQPGLAFAAVFAVTEEDDPRL
HHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEECEEEEEECCCCCEEEEEEEECCCCCCCC
SHFLVPLDAPGIRIIETWNATGMRATASHDIIFDNVAVPLDHRLDDQPAEGGVKRDETSM
EEEEEECCCCCEEEEEECCCCCCEECCCCCEEECCEECCCCCCCCCCCCCCCCCCCHHHH
AWASILIASVYDGIARSARDWIVDFVKNRVPGSLGAPLASVPRIRDAIGDIEVRLITNAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEECCHH
LLRSVAEDVDAGLPLGPAPASVRHVVIENAFAVTSLALELGGNPGVSRANPLERHHRNAL
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
TGRAHAPQGNLIRGIAARAILD
CCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]