Definition Beijerinckia indica subsp. indica ATCC 9039 chromosome, complete genome.
Accession NC_010581
Length 4,170,153

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The map label for this gene is dxs

Identifier: 182678782

GI number: 182678782

Start: 2059384

End: 2061312

Strand: Direct

Name: dxs

Synonym: Bind_1811

Alternate gene names: 182678782

Gene position: 2059384-2061312 (Clockwise)

Preceding gene: 182678778

Following gene: 182678783

Centisome position: 49.38

GC content: 60.13

Gene sequence:

>1929_bases
GTGAGGACAGATTCGAAGACTCCCCTTCTCGATACGATCGCCACTCCCACAGATCTCCGCCGTTTGAAGGAATCGGACCT
GGCGCAGCTCGCTGATGAGTTGCGTACTGAGACGATTGATGCGGTTTCGGTCACGGGTGGCCATCTCGGCGCCGGTCTCG
GCGTCGTCGAGTTGACAGTCGCCCTGCATTACGTTTTTGACACACCGCACGATCGGCTGATCTGGGACGTCGGTCATCAG
GCCTATCCGCACAAGATTCTGACGGGACGGCGTGACCGGATTCGCACGCTGCGGCGTGCAGGCGGATTGTCTGGATTCAC
CAAACGGTCCGAAAGCGTTTATGATCCCTTCGGCACCGCTCATTCCTCGACGTCGATCTCCGCTGGTCTCGGCATGGCAG
CGGCGACCACGCTTTCGGGTGGCAATAATAATGTTATCGCCGTGATTGGCGACGGCTCCATGTCAGCCGGCATGGCCTAT
GAGGCCATGAATAATGCCGGCGCCATGCATTCCCGTCTCATTATCATTTTGAATGATAATGAAATGTCGATCGCTCCGCC
GGCAGGAGCGCTTTCCGCTTATCTCGCTCGCCTTGTCTCGGGCGGCACCTATCGCACGGTTCGCGAAGCCGCCAAGCAGC
TTGGCCGGCATTTGCCGCATTTCATTTATGACCGCGCCCGCAAAACCGAGGAATTCGCCCGGAACTTCTGGGCCGGCGGC
ACGATGTTCGAGGAGCTTGGCATCTATTATGTCGGCCCGATCGACGGTCATAATCTCGACCATCTGCTGCCCGTCCTGAA
AAATGTCCGCGATTTCAAGGAAACGGGACCCATTCTCGTCCATGTCGTGACGCAAAAGGGCAAGGGCTATGCGCCGGCCG
CCGCGGCGAGCGACAAATATCACAGCGTCAATACCTTCGACGTCGTCACCGGTGTCCAGACCAAGCCCAAGGCCAACGCG
CCGTCTTATACGCGCGTCTTTGCCGATGCCCTGGTCAAGGAGGCCGAGCGCGACGACAAGATCGTGGCGATCACCGCCGC
CATGCCGGGGGGCACTGGCCTCGACGTGTTTGGCAAAGCCTTTCCTGAGCGCACATTCGACGTCGGCATTGCCGAGCAGC
ATGCCGTGACCTTCGCGGCTGGTCTCGCGACCGAAGGCTATCGCCCCTTCTGCGCCCTGTATTCCACCTTCCTTCAGCGC
GGCTATGATCAGGTCGTGCATGATGTGGCGATACAGAATCTGCCTGTTCGCTTCGCCATCGACCGCGCAGGCCTCGTCGG
CGCCGATGGCGCGACCCATGCGGGTTCGTTCGATGTGTCCTATCTCGGCATTTTGCCGAATATGGTGATCATGGCCGCCG
CCGATGAAGCGGAGCTCGTCCATATGGTCGCGACGGCCGCCGCCTATGATGAAGGCCCAATCGCTTTCCGTTATCCACGT
GGCGAGGGTGTCGGCATCGAATTGCCGCAAATCGGCGAAATTCTCGATATCGGCCGTGGCCGTATCGTGCGGGAAGGCAC
GACGGTAGCCCTCCTGTCGCTCGGGACGCGCCTTGCGGAAGCCTCAAAGGCGGCGGAGCAATTGGCGAGCTATGGCATTT
CCGTCACGGTCGCCGATGCGCGTTTCGCCAAGCCCCTCGATCTCGATCTCGTGCGGCGGCTCGCCAAGAATCATGAGGTT
TTGATCACCATCGAGGAAGGCAGCGTCGGCGGTTTCGGTTCCTTCGTCATGCAGGCCCTGGCCGAGGAAGGCTTGCTGGA
TGGAACGGGTCTCAAATTCCGCTCCATGGTTCTGCCTGACACGTTCCTCGATCACGACAAGCCGGAAAAGCTCTATGCCC
AGGCCGGCCTCGACGCCAAGGGCATTGTGGCCAAGGTTCTCGCGACGCTGGGACGCGAGAACGAAGCCCATCAAAGCCTG
ATTGCCTGA

Upstream 100 bases:

>100_bases
GCGAATAGAAAGCCCCTTTCGGCTTCTTCGCACATTCGGGGCGGCCTTTGCATGGATCGAGGATCGCCCATCACACGGAA
TTCCTATTGAAGAGGCGCCG

Downstream 100 bases:

>100_bases
GACGGAACCAGATCTCCCTTTTTCCGCAAGGATCGCCGCCGAAGCGCTCGCGGCCGTCCTTGCGGCTTTTCGGCGTGATG
GCACTGATATTCCATGGCTC

Product: 1-deoxy-D-xylulose-5-phosphate synthase

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MRTDSKTPLLDTIATPTDLRRLKESDLAQLADELRTETIDAVSVTGGHLGAGLGVVELTVALHYVFDTPHDRLIWDVGHQ
AYPHKILTGRRDRIRTLRRAGGLSGFTKRSESVYDPFGTAHSSTSISAGLGMAAATTLSGGNNNVIAVIGDGSMSAGMAY
EAMNNAGAMHSRLIIILNDNEMSIAPPAGALSAYLARLVSGGTYRTVREAAKQLGRHLPHFIYDRARKTEEFARNFWAGG
TMFEELGIYYVGPIDGHNLDHLLPVLKNVRDFKETGPILVHVVTQKGKGYAPAAAASDKYHSVNTFDVVTGVQTKPKANA
PSYTRVFADALVKEAERDDKIVAITAAMPGGTGLDVFGKAFPERTFDVGIAEQHAVTFAAGLATEGYRPFCALYSTFLQR
GYDQVVHDVAIQNLPVRFAIDRAGLVGADGATHAGSFDVSYLGILPNMVIMAAADEAELVHMVATAAAYDEGPIAFRYPR
GEGVGIELPQIGEILDIGRGRIVREGTTVALLSLGTRLAEASKAAEQLASYGISVTVADARFAKPLDLDLVRRLAKNHEV
LITIEEGSVGGFGSFVMQALAEEGLLDGTGLKFRSMVLPDTFLDHDKPEKLYAQAGLDAKGIVAKVLATLGRENEAHQSL
IA

Sequences:

>Translated_642_residues
MRTDSKTPLLDTIATPTDLRRLKESDLAQLADELRTETIDAVSVTGGHLGAGLGVVELTVALHYVFDTPHDRLIWDVGHQ
AYPHKILTGRRDRIRTLRRAGGLSGFTKRSESVYDPFGTAHSSTSISAGLGMAAATTLSGGNNNVIAVIGDGSMSAGMAY
EAMNNAGAMHSRLIIILNDNEMSIAPPAGALSAYLARLVSGGTYRTVREAAKQLGRHLPHFIYDRARKTEEFARNFWAGG
TMFEELGIYYVGPIDGHNLDHLLPVLKNVRDFKETGPILVHVVTQKGKGYAPAAAASDKYHSVNTFDVVTGVQTKPKANA
PSYTRVFADALVKEAERDDKIVAITAAMPGGTGLDVFGKAFPERTFDVGIAEQHAVTFAAGLATEGYRPFCALYSTFLQR
GYDQVVHDVAIQNLPVRFAIDRAGLVGADGATHAGSFDVSYLGILPNMVIMAAADEAELVHMVATAAAYDEGPIAFRYPR
GEGVGIELPQIGEILDIGRGRIVREGTTVALLSLGTRLAEASKAAEQLASYGISVTVADARFAKPLDLDLVRRLAKNHEV
LITIEEGSVGGFGSFVMQALAEEGLLDGTGLKFRSMVLPDTFLDHDKPEKLYAQAGLDAKGIVAKVLATLGRENEAHQSL
IA
>Mature_642_residues
MRTDSKTPLLDTIATPTDLRRLKESDLAQLADELRTETIDAVSVTGGHLGAGLGVVELTVALHYVFDTPHDRLIWDVGHQ
AYPHKILTGRRDRIRTLRRAGGLSGFTKRSESVYDPFGTAHSSTSISAGLGMAAATTLSGGNNNVIAVIGDGSMSAGMAY
EAMNNAGAMHSRLIIILNDNEMSIAPPAGALSAYLARLVSGGTYRTVREAAKQLGRHLPHFIYDRARKTEEFARNFWAGG
TMFEELGIYYVGPIDGHNLDHLLPVLKNVRDFKETGPILVHVVTQKGKGYAPAAAASDKYHSVNTFDVVTGVQTKPKANA
PSYTRVFADALVKEAERDDKIVAITAAMPGGTGLDVFGKAFPERTFDVGIAEQHAVTFAAGLATEGYRPFCALYSTFLQR
GYDQVVHDVAIQNLPVRFAIDRAGLVGADGATHAGSFDVSYLGILPNMVIMAAADEAELVHMVATAAAYDEGPIAFRYPR
GEGVGIELPQIGEILDIGRGRIVREGTTVALLSLGTRLAEASKAAEQLASYGISVTVADARFAKPLDLDLVRRLAKNHEV
LITIEEGSVGGFGSFVMQALAEEGLLDGTGLKFRSMVLPDTFLDHDKPEKLYAQAGLDAKGIVAKVLATLGRENEAHQSL
IA

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily

Homologues:

Organism=Homo sapiens, GI205277463, Length=642, Percent_Identity=23.208722741433, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4507521, Length=642, Percent_Identity=23.208722741433, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI225637463, Length=552, Percent_Identity=23.731884057971, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI225637459, Length=522, Percent_Identity=24.3295019157088, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI225637461, Length=522, Percent_Identity=24.3295019157088, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI133778974, Length=593, Percent_Identity=23.6087689713322, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI156564403, Length=279, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786622, Length=627, Percent_Identity=50.0797448165869, Blast_Score=608, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI17539652, Length=419, Percent_Identity=25.5369928400955, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551847, Length=593, Percent_Identity=25.4637436762226, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550715, Length=593, Percent_Identity=25.4637436762226, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24645119, Length=483, Percent_Identity=25.6728778467909, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24666278, Length=594, Percent_Identity=24.4107744107744, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DXS_BEII9 (B2IDK3)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001832928.1
- GeneID:   6201246
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1811
- HOGENOM:   HBG571647
- OMA:   QRFPDRY
- ProtClustDB:   PRK05444
- HAMAP:   MF_00315
- InterPro:   IPR001017
- InterPro:   IPR005477
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474
- Gene3D:   G3DSA:3.40.50.920
- SMART:   SM00861
- TIGRFAMs:   TIGR00204

Pfam domain/function: PF00676 E1_dh; PF02779 Transket_pyr; PF02780 Transketolase_C; SSF52922 Transketo_C_like

EC number: =2.2.1.7

Molecular weight: Translated: 68696; Mature: 68696

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00801 TRANSKETOLASE_1; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MRTDSKTPLLDTIATPTDLRRLKESDLAQLADELRTETIDAVSVTGGHLGAGLGVVELTV
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHH
ALHYVFDTPHDRLIWDVGHQAYPHKILTGRRDRIRTLRRAGGLSGFTKRSESVYDPFGTA
HHHHHCCCCCCCEEEECCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCC
HSSTSISAGLGMAAATTLSGGNNNVIAVIGDGSMSAGMAYEAMNNAGAMHSRLIIILNDN
CCCCCHHHCCCHHHHEEECCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEECCC
EMSIAPPAGALSAYLARLVSGGTYRTVREAAKQLGRHLPHFIYDRARKTEEFARNFWAGG
CEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
TMFEELGIYYVGPIDGHNLDHLLPVLKNVRDFKETGPILVHVVTQKGKGYAPAAAASDKY
CHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCC
HSVNTFDVVTGVQTKPKANAPSYTRVFADALVKEAERDDKIVAITAAMPGGTGLDVFGKA
CCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHH
FPERTFDVGIAEQHAVTFAAGLATEGYRPFCALYSTFLQRGYDQVVHDVAIQNLPVRFAI
CCCCHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DRAGLVGADGATHAGSFDVSYLGILPNMVIMAAADEAELVHMVATAAAYDEGPIAFRYPR
CCCCEECCCCCCCCCCCCCHHHHHHHCEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCC
GEGVGIELPQIGEILDIGRGRIVREGTTVALLSLGTRLAEASKAAEQLASYGISVTVADA
CCCCEECCCCHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECC
RFAKPLDLDLVRRLAKNHEVLITIEEGSVGGFGSFVMQALAEEGLLDGTGLKFRSMVLPD
CCCCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCH
TFLDHDKPEKLYAQAGLDAKGIVAKVLATLGRENEAHQSLIA
HHCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MRTDSKTPLLDTIATPTDLRRLKESDLAQLADELRTETIDAVSVTGGHLGAGLGVVELTV
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHH
ALHYVFDTPHDRLIWDVGHQAYPHKILTGRRDRIRTLRRAGGLSGFTKRSESVYDPFGTA
HHHHHCCCCCCCEEEECCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCC
HSSTSISAGLGMAAATTLSGGNNNVIAVIGDGSMSAGMAYEAMNNAGAMHSRLIIILNDN
CCCCCHHHCCCHHHHEEECCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEEEECCC
EMSIAPPAGALSAYLARLVSGGTYRTVREAAKQLGRHLPHFIYDRARKTEEFARNFWAGG
CEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCC
TMFEELGIYYVGPIDGHNLDHLLPVLKNVRDFKETGPILVHVVTQKGKGYAPAAAASDKY
CHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCC
HSVNTFDVVTGVQTKPKANAPSYTRVFADALVKEAERDDKIVAITAAMPGGTGLDVFGKA
CCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHH
FPERTFDVGIAEQHAVTFAAGLATEGYRPFCALYSTFLQRGYDQVVHDVAIQNLPVRFAI
CCCCHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DRAGLVGADGATHAGSFDVSYLGILPNMVIMAAADEAELVHMVATAAAYDEGPIAFRYPR
CCCCEECCCCCCCCCCCCCHHHHHHHCEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCC
GEGVGIELPQIGEILDIGRGRIVREGTTVALLSLGTRLAEASKAAEQLASYGISVTVADA
CCCCEECCCCHHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECC
RFAKPLDLDLVRRLAKNHEVLITIEEGSVGGFGSFVMQALAEEGLLDGTGLKFRSMVLPD
CCCCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCH
TFLDHDKPEKLYAQAGLDAKGIVAKVLATLGRENEAHQSLIA
HHCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA