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The map label for this gene is pgsA [H]

Identifier: 182678686

GI number: 182678686

Start: 1934514

End: 1935110

Strand: Direct

Name: pgsA [H]

Synonym: Bind_1713

Alternate gene names: 182678686

Gene position: 1934514-1935110 (Clockwise)

Preceding gene: 182678685

Following gene: 182678687

Centisome position: 46.39

GC content: 58.63

Gene sequence:

>597_bases
ATGGCGATTACCACGATCTCGCGAGGCTATGGGGGGACCTGGAGCCTGCCCAATATTTTGACTTATGGACGGCTGGTTGC
TGTGCCACTGGTCGTCGGCTGCCTGTTCTGGTCGGAATTCGATATTATGCGCTGGACAGCGCTCGGCCTCTTCATCGTGG
CCGGAATCACCGACTTTCTTGACGGCTATCTCGCTCGCGCGCTCGCTCAGCAATCGTCCCTCGGCCGTATGCTCGATCCG
ATCGCCGATAAGCTTCTCGTCGCCGCGGTGATCGTCATGCTGGTGGCCGATCATACGTTGCGCAGCTATTCACTTTGCGC
CGCCGTCGTCATTCTCTGCCGAGAAATCCTCGTCTCGGGCTTACGAGAATATCTCGCCGAACTCAAAGTGCCCGTGCCGG
TCAGCAAAGTCGCCAAATGGAAGACCACGGTGCAGCTCGTGGCGCTCGGTTTTCTCATCGCTGGCCCGGCGGGTGAAAGG
GTCCTTCCTGGCACGATCGTGATCGGCCTTGCCTTGTTCTGGGCCTCCGCGCTGCTTACCCTCTATACGGGTTGGGATTA
TCTGCGCGCTGGGGTCAAGCATGTGATTGACGAATAA

Upstream 100 bases:

>100_bases
TCCCGCGCGGCTTTGCCCGATCTCGAAAAAGTCCCGGGGATCAACGCCGCAAGCGCAAAGCTCATCTATGATTTTTTCCA
CGAGCGTGGCAAATAGAGGC

Downstream 100 bases:

>100_bases
AGCGCGCCGATCAAGGCAGGTATCGACGAGCGGCAATATGAAAGCGCTTTATTTTTCGTGGGTGCGCGAACGCATTGGCA
AGAGCGAGGAAGACATAACA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAITTISRGYGGTWSLPNILTYGRLVAVPLVVGCLFWSEFDIMRWTALGLFIVAGITDFLDGYLARALAQQSSLGRMLDP
IADKLLVAAVIVMLVADHTLRSYSLCAAVVILCREILVSGLREYLAELKVPVPVSKVAKWKTTVQLVALGFLIAGPAGER
VLPGTIVIGLALFWASALLTLYTGWDYLRAGVKHVIDE

Sequences:

>Translated_198_residues
MAITTISRGYGGTWSLPNILTYGRLVAVPLVVGCLFWSEFDIMRWTALGLFIVAGITDFLDGYLARALAQQSSLGRMLDP
IADKLLVAAVIVMLVADHTLRSYSLCAAVVILCREILVSGLREYLAELKVPVPVSKVAKWKTTVQLVALGFLIAGPAGER
VLPGTIVIGLALFWASALLTLYTGWDYLRAGVKHVIDE
>Mature_197_residues
AITTISRGYGGTWSLPNILTYGRLVAVPLVVGCLFWSEFDIMRWTALGLFIVAGITDFLDGYLARALAQQSSLGRMLDPI
ADKLLVAAVIVMLVADHTLRSYSLCAAVVILCREILVSGLREYLAELKVPVPVSKVAKWKTTVQLVALGFLIAGPAGERV
LPGTIVIGLALFWASALLTLYTGWDYLRAGVKHVIDE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=205, Percent_Identity=28.2926829268293, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI10092647, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788220, Length=190, Percent_Identity=37.3684210526316, Blast_Score=107, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320059, Length=158, Percent_Identity=33.5443037974684, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21478; Mature: 21347

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITTISRGYGGTWSLPNILTYGRLVAVPLVVGCLFWSEFDIMRWTALGLFIVAGITDFL
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGYLARALAQQSSLGRMLDPIADKLLVAAVIVMLVADHTLRSYSLCAAVVILCREILVSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREYLAELKVPVPVSKVAKWKTTVQLVALGFLIAGPAGERVLPGTIVIGLALFWASALLT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
LYTGWDYLRAGVKHVIDE
HHHCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AITTISRGYGGTWSLPNILTYGRLVAVPLVVGCLFWSEFDIMRWTALGLFIVAGITDFL
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGYLARALAQQSSLGRMLDPIADKLLVAAVIVMLVADHTLRSYSLCAAVVILCREILVSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREYLAELKVPVPVSKVAKWKTTVQLVALGFLIAGPAGERVLPGTIVIGLALFWASALLT
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
LYTGWDYLRAGVKHVIDE
HHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA