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The map label for this gene is pcp [H]

Identifier: 182678632

GI number: 182678632

Start: 1875325

End: 1876002

Strand: Direct

Name: pcp [H]

Synonym: Bind_1658

Alternate gene names: 182678632

Gene position: 1875325-1876002 (Clockwise)

Preceding gene: 182678630

Following gene: 182678635

Centisome position: 44.97

GC content: 59.73

Gene sequence:

>678_bases
ATGAGCCACACCGATGTGCGCCTTCTTGTCACGGGATTTGGCCGTTTTCCTGGCGCGCCGCGCAATCCAACGGCAACCCT
GATGCATCGGCTGACGCGCCATCATGCCCGCCTGGAACGGTTCGGCATTGATGTCACATGCGCCATTTTACCTGTGGTCT
ATGCGGACTTACCCGAACAGCTCGATAGCCTGCTGAATCATTCTCATCCCGACGGTGTTTTGCATTTCGGCCTGGCGCCC
CGGCGCACCGTCTTCAGCGTGGAAACGCGAGCCTTGAATCGCCGCTCTCCCTTGCGCTTCGATGCCGGCGGAGCACGGCC
GGCGCGAGCCTTTATCGCCGCGGGCGGTGCCTTCAGCCTGCACAGCCGCTTTCCCGCTCAGGCGATCACGACCACTCTGG
AACAGGCCCATATCCCCAGTGGTCTCTCTCGGGATGCCGGTGATTATCTGTGCAATATGGCGCTTTATTTGTCCTGCCGT
TCTGGGGTCGCATCCACCGGATTCATCCATGTGCCAGCGCGTGTTCGACCCCGACCCGACACCATGCCACAGCCTTTGAC
TCTGGCCATGCTGGAGCGCGCTGCCTTGATCACAATTTTCGTGATGGCTCATGATCTGCGCGTCAAACGAAGACTCGATC
GGACGAAGATTCAATCGTGCGATAAGGGCACGCCTTGA

Upstream 100 bases:

>100_bases
ACAGGTCTATCCTGATTGTCAGCGGGGGAAAGCCGAGTAAACTGGATCACCTTAGTTTGAAGAACCGGCGTCCCCAAGGG
CTTTCCCTATGAGGGTTTCC

Downstream 100 bases:

>100_bases
AGGCTCAATTTGAGCTTTCAAGCAGAGTTTTCAGATGAGTCAGGCCCTGCATGTAAAAATCACCCAGCTTCTCTGCCGCC
AGGGCCGGTGCAACACCCTC

Product: peptidase C15 pyroglutamyl peptidase I

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSHTDVRLLVTGFGRFPGAPRNPTATLMHRLTRHHARLERFGIDVTCAILPVVYADLPEQLDSLLNHSHPDGVLHFGLAP
RRTVFSVETRALNRRSPLRFDAGGARPARAFIAAGGAFSLHSRFPAQAITTTLEQAHIPSGLSRDAGDYLCNMALYLSCR
SGVASTGFIHVPARVRPRPDTMPQPLTLAMLERAALITIFVMAHDLRVKRRLDRTKIQSCDKGTP

Sequences:

>Translated_225_residues
MSHTDVRLLVTGFGRFPGAPRNPTATLMHRLTRHHARLERFGIDVTCAILPVVYADLPEQLDSLLNHSHPDGVLHFGLAP
RRTVFSVETRALNRRSPLRFDAGGARPARAFIAAGGAFSLHSRFPAQAITTTLEQAHIPSGLSRDAGDYLCNMALYLSCR
SGVASTGFIHVPARVRPRPDTMPQPLTLAMLERAALITIFVMAHDLRVKRRLDRTKIQSCDKGTP
>Mature_224_residues
SHTDVRLLVTGFGRFPGAPRNPTATLMHRLTRHHARLERFGIDVTCAILPVVYADLPEQLDSLLNHSHPDGVLHFGLAPR
RTVFSVETRALNRRSPLRFDAGGARPARAFIAAGGAFSLHSRFPAQAITTTLEQAHIPSGLSRDAGDYLCNMALYLSCRS
GVASTGFIHVPARVRPRPDTMPQPLTLAMLERAALITIFVMAHDLRVKRRLDRTKIQSCDKGTP

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 24788; Mature: 24657

Theoretical pI: Translated: 11.37; Mature: 11.37

Prosite motif: PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTDVRLLVTGFGRFPGAPRNPTATLMHRLTRHHARLERFGIDVTCAILPVVYADLPEQ
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LDSLLNHSHPDGVLHFGLAPRRTVFSVETRALNRRSPLRFDAGGARPARAFIAAGGAFSL
HHHHHCCCCCCCEEEECCCCCCEEEEHHHHHHCCCCCCEECCCCCCHHHHHEECCCCEEH
HSRFPAQAITTTLEQAHIPSGLSRDAGDYLCNMALYLSCRSGVASTGFIHVPARVRPRPD
HHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
TMPQPLTLAMLERAALITIFVMAHDLRVKRRLDRTKIQSCDKGTP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SHTDVRLLVTGFGRFPGAPRNPTATLMHRLTRHHARLERFGIDVTCAILPVVYADLPEQ
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LDSLLNHSHPDGVLHFGLAPRRTVFSVETRALNRRSPLRFDAGGARPARAFIAAGGAFSL
HHHHHCCCCCCCEEEECCCCCCEEEEHHHHHHCCCCCCEECCCCCCHHHHHEECCCCEEH
HSRFPAQAITTTLEQAHIPSGLSRDAGDYLCNMALYLSCRSGVASTGFIHVPARVRPRPD
HHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
TMPQPLTLAMLERAALITIFVMAHDLRVKRRLDRTKIQSCDKGTP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]