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The map label for this gene is hflX [H]

Identifier: 182678502

GI number: 182678502

Start: 1727458

End: 1728858

Strand: Direct

Name: hflX [H]

Synonym: Bind_1526

Alternate gene names: 182678502

Gene position: 1727458-1728858 (Clockwise)

Preceding gene: 182678501

Following gene: 182678506

Centisome position: 41.42

GC content: 61.03

Gene sequence:

>1401_bases
TTGCCGGGTGAATCCAACAAGGGTTCACCCGCTCTTACGCGGGCCGCCAAGACCCGCGCTATGGTTGTCGGCCCTTATCT
CAATCAGCGCGCAACGCAGCCCCATGGCCGATCGGCTGTTGCCCTTCCGGAGAAGGCGTTCCGGTCGCCGCAGGCGCGTT
TCGACGAAGTGCTTGGCCTCGCCGAAGCGCTCGACCTCGATATTGTCGACCAGCGCCTTTTGACGCTGGCTGAGATCAAG
CCCTCGACCTTCCTCGGCACCGGCAAGGTGGCCGAACTGGGTGAGGCCATCAAGGCCGCGGAGGCCGAGCTGGTCATCAT
GGACTGCGCCTTGTCTCCCGTGCAGCAGCGCAATCTTGAAAAAGCGCTCGGGGCCAAGGTGATCGATAGGACCGGCCTGA
TCCTCGAAATCTTCGGCCGCAGGGCGCGCACGCGCGAAGGCAGCTTGCAAGTCGAACTTGCTCATCTCGCCTATCAGAAA
TCACGTTTGGTGCGGTCCTGGACCCATCTCGAACGCCAGCGCGGCGGTTTCGGCTTCCTCGGCGGTCCTGGCGAAACGCA
AATCGAGGCCGACCGGCGCTTGTTGCAGGAACGCATGACGCGACTCGAGCAAGATCTTGCCGGAGTTAAGCGGACACGCG
GCCTGCACCGCAAGACGCGGCGTGATGTGCCTTACCCGATCATTGCGCTTGTCGGTTACACCAATGCCGGCAAATCGACC
CTGTTCAACCGTCTGACCGAGGCGGATGTGCTGGCGCAGAACATGCTCTTTGCGACGCTTGATCCGACCTTGCGGAGCCT
CACCTTGCCGCATGGGGCCAAGGTGATTCTCTCCGATACGGTGGGGTTCATTTCGGATCTGCCGACGATGCTGGTTTCAG
CTTTCCGCGCGACCCTTGAGGAGGTGCTGGAAGCCGATCTTATCCTGCACGTGCGCGATATCGCCCATCAGGATGCCGAG
GCCCAGTGTCAGGATGTGGAAAGTGTGCTCGCCGAACTCGGCATTGACATGGCCGACGAGCAGAGAATTCTGGAAGTCTG
GAACAAAGCTGATCTCCTCGATGAGGAGGCGCAAGCAGCAGCGCTCAATAATGCCAGGCGCTGGAAGAATGCCGAAAACC
AGCCGATTCTCGTCTCAGCGCTGACAGGGCAGGGAGTCGCAACCCTGGAGGCTGAAATCGAGGCGAGGCTTGCGCGGGGA
CGCCTGCTGTTCGATATCACGCTCGACCCGGCCAATGGCGAGGGCCTGCATTGGCTGCACGAACATACTGAGGTCATGCA
CAAAAGCATTGATGAGGATGGCACCATCCATGTCTCAGTGAGGGTGGCGCCGGAACGAGCTGAGCCGATCAAGCGGCGCT
TTGGCGCGATGCTGGTCGAGCGGGAAGGTTTAACCGCCTGA

Upstream 100 bases:

>100_bases
GGGAGAATCGGCTTCTACCGGTTTATTTTTGCGGACACAGGAGTTTCCCATAGACGCACCGACCGTTTCACCTTCGGCCA
GATTTTCGGGGACGAAGGGT

Downstream 100 bases:

>100_bases
TTTCTCGCTTTCCTTGGCCTGTTGCCATAGGGCATCCATTTCGGCCAGGTTCGCCTCTTCCAGCGTTTTGCCTTGCTCTC
TCAGCGCCGTTTCGATGAAA

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MPGESNKGSPALTRAAKTRAMVVGPYLNQRATQPHGRSAVALPEKAFRSPQARFDEVLGLAEALDLDIVDQRLLTLAEIK
PSTFLGTGKVAELGEAIKAAEAELVIMDCALSPVQQRNLEKALGAKVIDRTGLILEIFGRRARTREGSLQVELAHLAYQK
SRLVRSWTHLERQRGGFGFLGGPGETQIEADRRLLQERMTRLEQDLAGVKRTRGLHRKTRRDVPYPIIALVGYTNAGKST
LFNRLTEADVLAQNMLFATLDPTLRSLTLPHGAKVILSDTVGFISDLPTMLVSAFRATLEEVLEADLILHVRDIAHQDAE
AQCQDVESVLAELGIDMADEQRILEVWNKADLLDEEAQAAALNNARRWKNAENQPILVSALTGQGVATLEAEIEARLARG
RLLFDITLDPANGEGLHWLHEHTEVMHKSIDEDGTIHVSVRVAPERAEPIKRRFGAMLVEREGLTA

Sequences:

>Translated_466_residues
MPGESNKGSPALTRAAKTRAMVVGPYLNQRATQPHGRSAVALPEKAFRSPQARFDEVLGLAEALDLDIVDQRLLTLAEIK
PSTFLGTGKVAELGEAIKAAEAELVIMDCALSPVQQRNLEKALGAKVIDRTGLILEIFGRRARTREGSLQVELAHLAYQK
SRLVRSWTHLERQRGGFGFLGGPGETQIEADRRLLQERMTRLEQDLAGVKRTRGLHRKTRRDVPYPIIALVGYTNAGKST
LFNRLTEADVLAQNMLFATLDPTLRSLTLPHGAKVILSDTVGFISDLPTMLVSAFRATLEEVLEADLILHVRDIAHQDAE
AQCQDVESVLAELGIDMADEQRILEVWNKADLLDEEAQAAALNNARRWKNAENQPILVSALTGQGVATLEAEIEARLARG
RLLFDITLDPANGEGLHWLHEHTEVMHKSIDEDGTIHVSVRVAPERAEPIKRRFGAMLVEREGLTA
>Mature_465_residues
PGESNKGSPALTRAAKTRAMVVGPYLNQRATQPHGRSAVALPEKAFRSPQARFDEVLGLAEALDLDIVDQRLLTLAEIKP
STFLGTGKVAELGEAIKAAEAELVIMDCALSPVQQRNLEKALGAKVIDRTGLILEIFGRRARTREGSLQVELAHLAYQKS
RLVRSWTHLERQRGGFGFLGGPGETQIEADRRLLQERMTRLEQDLAGVKRTRGLHRKTRRDVPYPIIALVGYTNAGKSTL
FNRLTEADVLAQNMLFATLDPTLRSLTLPHGAKVILSDTVGFISDLPTMLVSAFRATLEEVLEADLILHVRDIAHQDAEA
QCQDVESVLAELGIDMADEQRILEVWNKADLLDEEAQAAALNNARRWKNAENQPILVSALTGQGVATLEAEIEARLARGR
LLFDITLDPANGEGLHWLHEHTEVMHKSIDEDGTIHVSVRVAPERAEPIKRRFGAMLVEREGLTA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=289, Percent_Identity=37.0242214532872, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI310133116, Length=298, Percent_Identity=35.9060402684564, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI310124269, Length=266, Percent_Identity=37.218045112782, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124267, Length=266, Percent_Identity=37.218045112782, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124171, Length=266, Percent_Identity=37.218045112782, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124169, Length=266, Percent_Identity=37.218045112782, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1790615, Length=364, Percent_Identity=45.6043956043956, Blast_Score=286, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17561038, Length=283, Percent_Identity=33.5689045936396, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24650079, Length=468, Percent_Identity=30.1282051282051, Blast_Score=161, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51390; Mature: 51258

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGESNKGSPALTRAAKTRAMVVGPYLNQRATQPHGRSAVALPEKAFRSPQARFDEVLGL
CCCCCCCCCHHHHHHHHCCEEEECCCHHCCCCCCCCCCEEECCHHHHCCHHHHHHHHHHH
AEALDLDIVDQRLLTLAEIKPSTFLGTGKVAELGEAIKAAEAELVIMDCALSPVQQRNLE
HHHHCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
KALGAKVIDRTGLILEIFGRRARTREGSLQVELAHLAYQKSRLVRSWTHLERQRGGFGFL
HHHHHHHHHCCCHHHHHHCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GGPGETQIEADRRLLQERMTRLEQDLAGVKRTRGLHRKTRRDVPYPIIALVGYTNAGKST
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHH
LFNRLTEADVLAQNMLFATLDPTLRSLTLPHGAKVILSDTVGFISDLPTMLVSAFRATLE
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
EVLEADLILHVRDIAHQDAEAQCQDVESVLAELGIDMADEQRILEVWNKADLLDEEAQAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
ALNNARRWKNAENQPILVSALTGQGVATLEAEIEARLARGRLLFDITLDPANGEGLHWLH
HHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHH
EHTEVMHKSIDEDGTIHVSVRVAPERAEPIKRRFGAMLVEREGLTA
HHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PGESNKGSPALTRAAKTRAMVVGPYLNQRATQPHGRSAVALPEKAFRSPQARFDEVLGL
CCCCCCCCHHHHHHHHCCEEEECCCHHCCCCCCCCCCEEECCHHHHCCHHHHHHHHHHH
AEALDLDIVDQRLLTLAEIKPSTFLGTGKVAELGEAIKAAEAELVIMDCALSPVQQRNLE
HHHHCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
KALGAKVIDRTGLILEIFGRRARTREGSLQVELAHLAYQKSRLVRSWTHLERQRGGFGFL
HHHHHHHHHCCCHHHHHHCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GGPGETQIEADRRLLQERMTRLEQDLAGVKRTRGLHRKTRRDVPYPIIALVGYTNAGKST
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHH
LFNRLTEADVLAQNMLFATLDPTLRSLTLPHGAKVILSDTVGFISDLPTMLVSAFRATLE
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
EVLEADLILHVRDIAHQDAEAQCQDVESVLAELGIDMADEQRILEVWNKADLLDEEAQAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHH
ALNNARRWKNAENQPILVSALTGQGVATLEAEIEARLARGRLLFDITLDPANGEGLHWLH
HHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHH
EHTEVMHKSIDEDGTIHVSVRVAPERAEPIKRRFGAMLVEREGLTA
HHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]