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The map label for this gene is yafC [H]

Identifier: 182678458

GI number: 182678458

Start: 1685893

End: 1686798

Strand: Direct

Name: yafC [H]

Synonym: Bind_1481

Alternate gene names: 182678458

Gene position: 1685893-1686798 (Clockwise)

Preceding gene: 182678453

Following gene: 182678459

Centisome position: 40.43

GC content: 63.91

Gene sequence:

>906_bases
ATGAAAATCGACCTCAACGACTATGCCTATTTTGCCGAGGTTGTCGCCCATGGCGGGTTTGCCGCAGCTGGGCGCGCGCT
CCGCGAGCCAAAGTCCAAGCTCAGCCGGCGCATTGCTGGGTTGGAGGATCGGTTGGGACTGCGCTTGATAGAGCGGTCCA
GCAGGCGCTTTCGCGTGACAGACACGGGCCAGGCCTTTTACGAGAGATGCCGGGCGATGCTGGCCGAGGCGGAGCAGGCG
GAGGCATTGGTCATGCAGGCTCAGGCCGAGCCCCATGGTCGCATCCGATTCAGCTGCCCGACGGGCATGCTGGAGCCGAT
CTCGGGCCTGATCTCGTCTTTCCTGGTCCGCTATCCGAAGGTGCGGCTCCAGCTCGTGGCAACGGATCGGGCACTCAACC
TGATCGAGGAACGGATCGATCTGGCACTCCGGGTGCGCGGGAGCCTTACCAGCGACGCCGCGCTGACAATGCGATCACTC
GGCCTATCCACCCGCATCCTCGTCGCCAGCCCCCTGATCGCCAGCCAGGTGGGAAGCATCGAGCAATTGGCCTTATTCCC
CGCTTTGGCGACCAATGACACGGCGGACGATCTCGAATGGCACCTGGAAACGGAAGACGGCCTCAAGCAGGTCATCCGCG
TTGAACCGCGAATGGGATGCGAGGACATGGCCACCGTGCGCGCCGCCGCCATCGACGGCATCGGGGTGGCGATTCTGCCC
GATCATGTCTGTCTTGATGCATTGGAAGCGGGACGCCTGGTGCGCGTGCTGCCGGCATGGCGCGGACTACAGGGGATCGT
GCATCTCGTCTTCACGACCCGGCGCGGTTTGCCACCGGCCGTCCGCGCACTCATTGACCATCTGGCTGCCGGCTTTCCGC
GCGACGTCTTGGGGAAGAATGCGTAA

Upstream 100 bases:

>100_bases
AATGGTCGGCGAAGCGCCGGTGCCCCTCGTAGATGCAATGAGAACGATGATGCGTGTAGTCGGTGGATATGGCACTTAGC
GTTCTAATGGAGGAACGCTG

Downstream 100 bases:

>100_bases
AGCCGCGACCAATGGATCCGGTGGAGACGGCGACTGATCCGCCTGTTAAAAGTAATCCCGCTAGTTTGGCTTCACGCGCC
ATTTGAGAACGAAGCTGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKIDLNDYAYFAEVVAHGGFAAAGRALREPKSKLSRRIAGLEDRLGLRLIERSSRRFRVTDTGQAFYERCRAMLAEAEQA
EALVMQAQAEPHGRIRFSCPTGMLEPISGLISSFLVRYPKVRLQLVATDRALNLIEERIDLALRVRGSLTSDAALTMRSL
GLSTRILVASPLIASQVGSIEQLALFPALATNDTADDLEWHLETEDGLKQVIRVEPRMGCEDMATVRAAAIDGIGVAILP
DHVCLDALEAGRLVRVLPAWRGLQGIVHLVFTTRRGLPPAVRALIDHLAAGFPRDVLGKNA

Sequences:

>Translated_301_residues
MKIDLNDYAYFAEVVAHGGFAAAGRALREPKSKLSRRIAGLEDRLGLRLIERSSRRFRVTDTGQAFYERCRAMLAEAEQA
EALVMQAQAEPHGRIRFSCPTGMLEPISGLISSFLVRYPKVRLQLVATDRALNLIEERIDLALRVRGSLTSDAALTMRSL
GLSTRILVASPLIASQVGSIEQLALFPALATNDTADDLEWHLETEDGLKQVIRVEPRMGCEDMATVRAAAIDGIGVAILP
DHVCLDALEAGRLVRVLPAWRGLQGIVHLVFTTRRGLPPAVRALIDHLAAGFPRDVLGKNA
>Mature_301_residues
MKIDLNDYAYFAEVVAHGGFAAAGRALREPKSKLSRRIAGLEDRLGLRLIERSSRRFRVTDTGQAFYERCRAMLAEAEQA
EALVMQAQAEPHGRIRFSCPTGMLEPISGLISSFLVRYPKVRLQLVATDRALNLIEERIDLALRVRGSLTSDAALTMRSL
GLSTRILVASPLIASQVGSIEQLALFPALATNDTADDLEWHLETEDGLKQVIRVEPRMGCEDMATVRAAAIDGIGVAILP
DHVCLDALEAGRLVRVLPAWRGLQGIVHLVFTTRRGLPPAVRALIDHLAAGFPRDVLGKNA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=298, Percent_Identity=30.8724832214765, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=28.1786941580756, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI145693193, Length=305, Percent_Identity=26.8852459016393, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=26.6211604095563, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789440, Length=261, Percent_Identity=27.2030651340996, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=27.7027027027027, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787128, Length=310, Percent_Identity=22.9032258064516, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789173, Length=255, Percent_Identity=27.0588235294118, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32935; Mature: 32935

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDLNDYAYFAEVVAHGGFAAAGRALREPKSKLSRRIAGLEDRLGLRLIERSSRRFRVT
CEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEE
DTGQAFYERCRAMLAEAEQAEALVMQAQAEPHGRIRFSCPTGMLEPISGLISSFLVRYPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCC
VRLQLVATDRALNLIEERIDLALRVRGSLTSDAALTMRSLGLSTRILVASPLIASQVGSI
CEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEHHHHCCHHHHHHCCH
EQLALFPALATNDTADDLEWHLETEDGLKQVIRVEPRMGCEDMATVRAAAIDGIGVAILP
HHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECC
DHVCLDALEAGRLVRVLPAWRGLQGIVHLVFTTRRGLPPAVRALIDHLAAGFPRDVLGKN
HHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCC
A
C
>Mature Secondary Structure
MKIDLNDYAYFAEVVAHGGFAAAGRALREPKSKLSRRIAGLEDRLGLRLIERSSRRFRVT
CEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEE
DTGQAFYERCRAMLAEAEQAEALVMQAQAEPHGRIRFSCPTGMLEPISGLISSFLVRYPK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCC
VRLQLVATDRALNLIEERIDLALRVRGSLTSDAALTMRSLGLSTRILVASPLIASQVGSI
CEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEHHHHCCHHHHHHCCH
EQLALFPALATNDTADDLEWHLETEDGLKQVIRVEPRMGCEDMATVRAAAIDGIGVAILP
HHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECC
DHVCLDALEAGRLVRVLPAWRGLQGIVHLVFTTRRGLPPAVRALIDHLAAGFPRDVLGKN
HHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]