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The map label for this gene is panC [H]

Identifier: 182678304

GI number: 182678304

Start: 1532597

End: 1533451

Strand: Direct

Name: panC [H]

Synonym: Bind_1321

Alternate gene names: 182678304

Gene position: 1532597-1533451 (Clockwise)

Preceding gene: 182678302

Following gene: 182678305

Centisome position: 36.75

GC content: 58.95

Gene sequence:

>855_bases
ATGAATGATAATCACATCGAAATCCTGCGGGATCCGGCATCTTTGCAGGCCAAGATCGCGCATTGGCGTAGTCAAGGACA
GCGTATTGTCCTGGTGCCGACCATGGGTGCCTTGCACGCCGGGCATATGTCTTTGGTGAAAGAAGCCAAACGGCTTGGCG
ACCGCGTGCTTTTGTCGATTTTCGTTAATCCAACCCAATTCGCGCCGAACGAGGATTATGCGGTCTATCCGCGCCGTCTC
GAAGCCGATGCCGAGCTCTCGACCGAGGCCGGGGCCGATCTGATCTTCGCTCCGACACCGGAGATCATGTATCCGGCCGG
TTTTGCGACAACCATTTCCCTGACGGGTCCGGCAACGGCCGGGCTCGAGGATAAGTTCCGGCCGACTCATTTCGCTGGTG
TCGCGACGGTGGTCGCCAAGCTGCTCAATCTCGCGCGGGCCGATGTCGCGATTTTCGGCCAAAAGGATTATCAGCAGCTT
CAGGTCATCCAGCAGATGGTGAGTGATCTCGCCATTCCGGTCGAGATCGTGGGGGCGCCAACCATGCGCGAGAAGGACGG
GCTCGCGCTTTCCTCGCGCAATTTCTATCTGACCGTCGCCGAGCGTGATGCCGCGCCGCGCCTCTATGCGGCTCTCGTGC
AATGCGCTCGGGATATCGCGCGTGGCGAAACCATCAATAAAGCCCTGGCGAACGCTATGGAGAGCGTAATCGCCGCGGGT
TTTGTGATCGATTATATCGAGGCCCGCCATGCCGAAACTTTGGCGCTGGTCGAAAATAGCGGCGAGGGGCCGATCCGCCT
GCTCGCGGCGGCCAAGCTCGGCACGACACGTCTTATTGACAATATTGCTGTATGA

Upstream 100 bases:

>100_bases
CGTCTCCCTCCATACTGTCGTTTGGCGGGGCCGCATTCCCTCCTCGCCCGCACTTTCGCCTTGGCCGAATGGCCGCGTTC
CAATGACCAGAATCGTCCCC

Downstream 100 bases:

>100_bases
GTGAGCCGGAATGAGCGCGGAATTGATCGTTCATTTGCGCGTCGGTGGCCGTGTTCAGGGTGTCGGTTACCGTGCCTGGA
CCGTTGCCGAGGCGCGTCGT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNDNHIEILRDPASLQAKIAHWRSQGQRIVLVPTMGALHAGHMSLVKEAKRLGDRVLLSIFVNPTQFAPNEDYAVYPRRL
EADAELSTEAGADLIFAPTPEIMYPAGFATTISLTGPATAGLEDKFRPTHFAGVATVVAKLLNLARADVAIFGQKDYQQL
QVIQQMVSDLAIPVEIVGAPTMREKDGLALSSRNFYLTVAERDAAPRLYAALVQCARDIARGETINKALANAMESVIAAG
FVIDYIEARHAETLALVENSGEGPIRLLAAAKLGTTRLIDNIAV

Sequences:

>Translated_284_residues
MNDNHIEILRDPASLQAKIAHWRSQGQRIVLVPTMGALHAGHMSLVKEAKRLGDRVLLSIFVNPTQFAPNEDYAVYPRRL
EADAELSTEAGADLIFAPTPEIMYPAGFATTISLTGPATAGLEDKFRPTHFAGVATVVAKLLNLARADVAIFGQKDYQQL
QVIQQMVSDLAIPVEIVGAPTMREKDGLALSSRNFYLTVAERDAAPRLYAALVQCARDIARGETINKALANAMESVIAAG
FVIDYIEARHAETLALVENSGEGPIRLLAAAKLGTTRLIDNIAV
>Mature_284_residues
MNDNHIEILRDPASLQAKIAHWRSQGQRIVLVPTMGALHAGHMSLVKEAKRLGDRVLLSIFVNPTQFAPNEDYAVYPRRL
EADAELSTEAGADLIFAPTPEIMYPAGFATTISLTGPATAGLEDKFRPTHFAGVATVVAKLLNLARADVAIFGQKDYQQL
QVIQQMVSDLAIPVEIVGAPTMREKDGLALSSRNFYLTVAERDAAPRLYAALVQCARDIARGETINKALANAMESVIAAG
FVIDYIEARHAETLALVENSGEGPIRLLAAAKLGTTRLIDNIAV

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=272, Percent_Identity=46.6911764705882, Blast_Score=230, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6322046, Length=314, Percent_Identity=37.2611464968153, Blast_Score=179, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 30697; Mature: 30697

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNHIEILRDPASLQAKIAHWRSQGQRIVLVPTMGALHAGHMSLVKEAKRLGDRVLLSI
CCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEE
FVNPTQFAPNEDYAVYPRRLEADAELSTEAGADLIFAPTPEIMYPAGFATTISLTGPATA
EECCCCCCCCCCCEECCHHCCCCCCCCCCCCCCEEEECCCCCEECCCCEEEEEECCCCCC
GLEDKFRPTHFAGVATVVAKLLNLARADVAIFGQKDYQQLQVIQQMVSDLAIPVEIVGAP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCC
TMREKDGLALSSRNFYLTVAERDAAPRLYAALVQCARDIARGETINKALANAMESVIAAG
CCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FVIDYIEARHAETLALVENSGEGPIRLLAAAKLGTTRLIDNIAV
HHHHHHHHHCCCEEEEEECCCCCCEEEEEEHHCCHHHHHHHHCC
>Mature Secondary Structure
MNDNHIEILRDPASLQAKIAHWRSQGQRIVLVPTMGALHAGHMSLVKEAKRLGDRVLLSI
CCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEE
FVNPTQFAPNEDYAVYPRRLEADAELSTEAGADLIFAPTPEIMYPAGFATTISLTGPATA
EECCCCCCCCCCCEECCHHCCCCCCCCCCCCCCEEEECCCCCEECCCCEEEEEECCCCCC
GLEDKFRPTHFAGVATVVAKLLNLARADVAIFGQKDYQQLQVIQQMVSDLAIPVEIVGAP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHHHHHCCCEEEECCC
TMREKDGLALSSRNFYLTVAERDAAPRLYAALVQCARDIARGETINKALANAMESVIAAG
CCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FVIDYIEARHAETLALVENSGEGPIRLLAAAKLGTTRLIDNIAV
HHHHHHHHHCCCEEEEEECCCCCCEEEEEEHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA