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The map label for this gene is srpA [H]

Identifier: 182678255

GI number: 182678255

Start: 1478659

End: 1479777

Strand: Direct

Name: srpA [H]

Synonym: Bind_1271

Alternate gene names: 182678255

Gene position: 1478659-1479777 (Clockwise)

Preceding gene: 182678249

Following gene: 182678256

Centisome position: 35.46

GC content: 60.86

Gene sequence:

>1119_bases
ATGTCCCAGTTTCCTGGTCCATCAAAAAGCGCGCCTGCGCCTTTGTCGTCCACGGCCCTTGTCCTGCGCTTTGGTGTAAT
CGGCGCCATTGTCTGCGCCGGCGCGGCCGCCTTTGCTTATGCGGGCGGCTGGTTCTCCCCCGCGCGGCTGACGCCCAGCC
GGTTAATCGAAACATTCCAGGAGGTCAACGGCTTCTATCCGGGATTTCGGCGCAATCACGCGAAGGGCATCTGCTTTTCA
GGCCATTTCGAGAGCAATGGCCAGGGCGCTGACCTCTCGAAAGCCAGCTTGTTCGCTCCAGGCCGCGTCACCCCAGTCAC
CGGCCGTTTCGCCTTGGCGGGTGGCCAGCCCTACGCAGCCGATGCCGAGACGACAGTGCGCAGCATGGCGGTCCGCTTCC
GGCTCGACAATGGCGAAGAATGGCGAACCGGCATGAATGATATTCCTGTCTTCGCAGTAAACACGCCTGAGGCCTTTCGA
GATCAGCTCCTGGCGGGGCGAAAGGATCCTGCGACCGGCAAGCCGGATCCCGCCGCAATGGCGGCTTTTCTCGCAGCGCA
TCCTGAGACAGCGCGGGCCGCGGCCCTGATCAAGGCCCGCAGCATTTCCTCGGGCTTCGACGATGATACTTACAACGGCC
TCAATACGTTCCTGTTTGTCAATTCGGCCGGTGTCGCGACGCCCGTGCGTTGGTCGATGGTGCCCATCGCCCCCTTCATT
AGCGAGGAACCGGAAAAAACCGTGAAGATCGACAAGGATTTCCTGTTCGTTGATCTGATCAATGAAGCTGGGGACCATCC
TCTGCAATGGCGTCTCGTCGTTATGGTCGGAAAGCCGGGTGATCCCACGATGGACGCGACGCTTCCCTGGCCGAGCGAGC
GTGAGCACCGGGAACTTGGCAGTCTTACAATAGAAAGCCTTCAGGATGAAGCCGATGGGCGCTGCCGCGACGTCAATTTC
GACCCGCTCATCCTGCCGCAGGGCATTGAGGCCTCGGACGATCCGCTGCTGAGCGCGCGATCGGCCGTTTATTCACAATC
CTTTACCCGCCGCGAGGGCGAGCCCAAAACACCGAGCGCCGTGATGATGCCGAATGGGACGAAAGGGGACAAATCATGA

Upstream 100 bases:

>100_bases
GATCGATTTTGGAGATCGATTTTTTAATAAGGGTGAATTGGATTTGGAACGGCGCTTCGGCGATGATCGAAGCAAGCACT
TATCAAGTGAGCAAATCCCC

Downstream 100 bases:

>100_bases
AAGCCGCGACTCATTTCCATGGCCTGTCCCGTGCCTTGCACTGGATCATGGCTGTTTTGATCCTCGCTATGCTGTTCATC
GGCGTCAGCATGGTCTCCCG

Product: catalase domain-containing protein

Products: H2O; O2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSQFPGPSKSAPAPLSSTALVLRFGVIGAIVCAGAAAFAYAGGWFSPARLTPSRLIETFQEVNGFYPGFRRNHAKGICFS
GHFESNGQGADLSKASLFAPGRVTPVTGRFALAGGQPYAADAETTVRSMAVRFRLDNGEEWRTGMNDIPVFAVNTPEAFR
DQLLAGRKDPATGKPDPAAMAAFLAAHPETARAAALIKARSISSGFDDDTYNGLNTFLFVNSAGVATPVRWSMVPIAPFI
SEEPEKTVKIDKDFLFVDLINEAGDHPLQWRLVVMVGKPGDPTMDATLPWPSEREHRELGSLTIESLQDEADGRCRDVNF
DPLILPQGIEASDDPLLSARSAVYSQSFTRREGEPKTPSAVMMPNGTKGDKS

Sequences:

>Translated_372_residues
MSQFPGPSKSAPAPLSSTALVLRFGVIGAIVCAGAAAFAYAGGWFSPARLTPSRLIETFQEVNGFYPGFRRNHAKGICFS
GHFESNGQGADLSKASLFAPGRVTPVTGRFALAGGQPYAADAETTVRSMAVRFRLDNGEEWRTGMNDIPVFAVNTPEAFR
DQLLAGRKDPATGKPDPAAMAAFLAAHPETARAAALIKARSISSGFDDDTYNGLNTFLFVNSAGVATPVRWSMVPIAPFI
SEEPEKTVKIDKDFLFVDLINEAGDHPLQWRLVVMVGKPGDPTMDATLPWPSEREHRELGSLTIESLQDEADGRCRDVNF
DPLILPQGIEASDDPLLSARSAVYSQSFTRREGEPKTPSAVMMPNGTKGDKS
>Mature_371_residues
SQFPGPSKSAPAPLSSTALVLRFGVIGAIVCAGAAAFAYAGGWFSPARLTPSRLIETFQEVNGFYPGFRRNHAKGICFSG
HFESNGQGADLSKASLFAPGRVTPVTGRFALAGGQPYAADAETTVRSMAVRFRLDNGEEWRTGMNDIPVFAVNTPEAFRD
QLLAGRKDPATGKPDPAAMAAFLAAHPETARAAALIKARSISSGFDDDTYNGLNTFLFVNSAGVATPVRWSMVPIAPFIS
EEPEKTVKIDKDFLFVDLINEAGDHPLQWRLVVMVGKPGDPTMDATLPWPSEREHRELGSLTIESLQDEADGRCRDVNFD
PLILPQGIEASDDPLLSARSAVYSQSFTRREGEPKTPSAVMMPNGTKGDKS

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=311, Percent_Identity=27.3311897106109, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI48994891, Length=301, Percent_Identity=25.2491694352159, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71998444, Length=306, Percent_Identity=26.4705882352941, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25147792, Length=306, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25151141, Length=306, Percent_Identity=25.4901960784314, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920968, Length=298, Percent_Identity=26.510067114094, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17981717, Length=309, Percent_Identity=24.9190938511327, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6 [C]

Molecular weight: Translated: 39980; Mature: 39849

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFPGPSKSAPAPLSSTALVLRFGVIGAIVCAGAAAFAYAGGWFSPARLTPSRLIETFQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EVNGFYPGFRRNHAKGICFSGHFESNGQGADLSKASLFAPGRVTPVTGRFALAGGQPYAA
HHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCC
DAETTVRSMAVRFRLDNGEEWRTGMNDIPVFAVNTPEAFRDQLLAGRKDPATGKPDPAAM
CHHHHHHEEEEEEEECCCHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCHHHH
AAFLAAHPETARAAALIKARSISSGFDDDTYNGLNTFLFVNSAGVATPVRWSMVPIAPFI
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCHHH
SEEPEKTVKIDKDFLFVDLINEAGDHPLQWRLVVMVGKPGDPTMDATLPWPSEREHRELG
CCCCCHHEEECCCEEEEEEHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHH
SLTIESLQDEADGRCRDVNFDPLILPQGIEASDDPLLSARSAVYSQSFTRREGEPKTPSA
HHHHHHHHHHCCCCEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCE
VMMPNGTKGDKS
EECCCCCCCCCC
>Mature Secondary Structure 
SQFPGPSKSAPAPLSSTALVLRFGVIGAIVCAGAAAFAYAGGWFSPARLTPSRLIETFQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EVNGFYPGFRRNHAKGICFSGHFESNGQGADLSKASLFAPGRVTPVTGRFALAGGQPYAA
HHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCC
DAETTVRSMAVRFRLDNGEEWRTGMNDIPVFAVNTPEAFRDQLLAGRKDPATGKPDPAAM
CHHHHHHEEEEEEEECCCHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCHHHH
AAFLAAHPETARAAALIKARSISSGFDDDTYNGLNTFLFVNSAGVATPVRWSMVPIAPFI
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCHHH
SEEPEKTVKIDKDFLFVDLINEAGDHPLQWRLVVMVGKPGDPTMDATLPWPSEREHRELG
CCCCCHHEEECCCEEEEEEHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHH
SLTIESLQDEADGRCRDVNFDPLILPQGIEASDDPLLSARSAVYSQSFTRREGEPKTPSA
HHHHHHHHHHCCCCEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCE
VMMPNGTKGDKS
EECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: Hydrogen peroxide [C]

Specific reaction: (2) Hydrogen peroxide --> (2) H2O + O2 [C]

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]