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The map label for this gene is kup2 [H]

Identifier: 182678246

GI number: 182678246

Start: 1464889

End: 1466820

Strand: Direct

Name: kup2 [H]

Synonym: Bind_1262

Alternate gene names: 182678246

Gene position: 1464889-1466820 (Clockwise)

Preceding gene: 182678244

Following gene: 182678247

Centisome position: 35.13

GC content: 58.23

Gene sequence:

>1932_bases
ATGACGCAGCAGATCGCTCAAGACCAGGGCTCATTGGATGTATCTGTCCCATGTCCGGCGCCCGTGCCGCCGCATGTCCA
ACATGAAGGCTTCGGCGGTCTGGTGCTTGGCTCGATCGGCGTCGTTTACGGCGATATCGGCACGAGCCCGCTCTATGCGT
TGCGGGAATCGCTCAAACATGTCGAGGAAGCTGGCATCTCCGACATGAGCGTGATCGGCACGATTTCCCTGCTGCTCTGG
GCGCTCTTCTTCACCGTTACGGCCAAATATGTTCTGTTCCTGATGCAGGCCGATAACAAGGGTGAGGGCGGCATTCTTTC
GCTGATGGCGCTCGCGCAAAAAGCCCTGGGCCACAGAGCCATATCAGTGTTCTTTCTTGGGGTTGCCGGCGCGGCTCTGT
TTTCCGGCGATGCGATCATCACCCCCGCCATTTCCGTTCTGTCGGCCCTCGAAGGGTTGGAGACCGTCGCGCCGCATCTC
GAACCCTATATTCTGCCGGTGACGGTCGTCATTCTGGTCTCGGTTTTCTGGGTTCAGAGCCATGGAACCGCGCGGGTCGC
CGCCTTTTTTGGCCCGATCATGGCGGTTTTTTTCCTTGTCATCGGTGGTCTTGGCCTCATGCATATTGCCGATGCGCCGC
GTGTTCTGCAGGCCTTCGATCCGACGCACGGCCTGCATTTCCTCTTCAGCCATGGCATGATGGGCTTCATGGTCTTGGGC
TCGGTTTTCCTGGCCGTGACGGGTGCCGAGGCGCTTTATGCTGATATGGGCCATTTCGGTCGCAAGCCGATTCAATATGC
CTGGATCTTCTTCATTTTGCCCGCGCTCAGCCTCAACTATCTTGGCCAGGGCGCGCTCCTGCTTTCGCATCCGGCCGCGG
TCGAAAATCCCTTCTTCCTGCTGGCGCCCCCCTGGGCTTTGTTGCCCCTCGTCATTCTTGCGACCCTGGCGACCGTCATT
GCCAGCCAGGCGGTGATCACAGGCGCCTTTTCTCTGGTGCGCCAGGCGATTCAGCTTGGGCTTCTGCCGCGCATGTTGAT
CCTGCATACGTCCGAGACGCAGGAAGGGCAGATTTTCATCCCGCGCCTCAATCGCCTTCTGCTGATCGGCGTTCTCGTTC
TTGTTTTCGTGTTCAAGAATTCCAGTGCCTTGGCCTCGGCTTATGGCATTGCCGTCACCTGCACCATGGTGGTGACGACG
GCACTCGCCTTTGTGGTGGTCTGGAAATTGTGGAAATGGCCACTCTGGGGCGCTATTGCGTTCGTCTCGGCTTTTCTCGT
CATCGATGTCGCCTTTCTGGCCGCTAACCTCCTCAAGATCGTCGATGGCGGCTGGGTGCCGCTGCTTCTCGGCTGCATGG
TGATGGTGGTGATGTGGACCTGGGTGCGCGGCACGAAATTGCTGAACGCCAAATCACGCCGCGATTCGATTTCCCTGCAG
GATTTGATTCACATGCTGGAGAAATCCAAGCCGACGCGGGTTAAGGGCACGGCGATCTTTCTCACCAGCACGCCGGAGAC
CGCGCCTTCGGCATTCATGCATAATCTGAAACATAACAAGGTCATGCATGAACGCGTGCTGATCATGTCGGTGCAAACCG
AGGACATGCCCCGCGTCGCGCCCGCGAACCGCTATGAGATCGAACAATTGTCGGAGGATTTCACGCGGGTCATCCTGCAT
TACGGCTATATGGAAAGTCCGAGGATCCCGGCAGCGCTCGCGATTCTGCGCAAGTCGGGCTTGAAGTTCGACATTATGAC
GACGTCCTTCTTCCTCGGCCGCCGATCGATCAAGCCCGCACCCAATTCCAGCATGCCCATCTGGCAGGACAAATTGTTCA
TCGCTCTATCGAAACAGGCCGCCAATGCGACGGACTTCTTCTCGATCCCCTCGGACCGTGTGGTGGAGCTCGGCGCGCAG
GTGACGATTTAA

Upstream 100 bases:

>100_bases
TCCTTTCTCGAATTGTCGTTTGCTGCATAAGGCAAAGATTCGAGATGGGCTCCGATGATTTTTTGTGACCATCGGGGTTG
GACTTCGACAAGGATTCACC

Downstream 100 bases:

>100_bases
TCCAGCGCGATTTTTCGCTTATCCACGCCTGAAACAGGGCTGAGCCGTGCATCGGGCCATGGGCTTTGCTAAAGTGCACC
CATGCCGAAACCCGTCGTCG

Product: K potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MTQQIAQDQGSLDVSVPCPAPVPPHVQHEGFGGLVLGSIGVVYGDIGTSPLYALRESLKHVEEAGISDMSVIGTISLLLW
ALFFTVTAKYVLFLMQADNKGEGGILSLMALAQKALGHRAISVFFLGVAGAALFSGDAIITPAISVLSALEGLETVAPHL
EPYILPVTVVILVSVFWVQSHGTARVAAFFGPIMAVFFLVIGGLGLMHIADAPRVLQAFDPTHGLHFLFSHGMMGFMVLG
SVFLAVTGAEALYADMGHFGRKPIQYAWIFFILPALSLNYLGQGALLLSHPAAVENPFFLLAPPWALLPLVILATLATVI
ASQAVITGAFSLVRQAIQLGLLPRMLILHTSETQEGQIFIPRLNRLLLIGVLVLVFVFKNSSALASAYGIAVTCTMVVTT
ALAFVVVWKLWKWPLWGAIAFVSAFLVIDVAFLAANLLKIVDGGWVPLLLGCMVMVVMWTWVRGTKLLNAKSRRDSISLQ
DLIHMLEKSKPTRVKGTAIFLTSTPETAPSAFMHNLKHNKVMHERVLIMSVQTEDMPRVAPANRYEIEQLSEDFTRVILH
YGYMESPRIPAALAILRKSGLKFDIMTTSFFLGRRSIKPAPNSSMPIWQDKLFIALSKQAANATDFFSIPSDRVVELGAQ
VTI

Sequences:

>Translated_643_residues
MTQQIAQDQGSLDVSVPCPAPVPPHVQHEGFGGLVLGSIGVVYGDIGTSPLYALRESLKHVEEAGISDMSVIGTISLLLW
ALFFTVTAKYVLFLMQADNKGEGGILSLMALAQKALGHRAISVFFLGVAGAALFSGDAIITPAISVLSALEGLETVAPHL
EPYILPVTVVILVSVFWVQSHGTARVAAFFGPIMAVFFLVIGGLGLMHIADAPRVLQAFDPTHGLHFLFSHGMMGFMVLG
SVFLAVTGAEALYADMGHFGRKPIQYAWIFFILPALSLNYLGQGALLLSHPAAVENPFFLLAPPWALLPLVILATLATVI
ASQAVITGAFSLVRQAIQLGLLPRMLILHTSETQEGQIFIPRLNRLLLIGVLVLVFVFKNSSALASAYGIAVTCTMVVTT
ALAFVVVWKLWKWPLWGAIAFVSAFLVIDVAFLAANLLKIVDGGWVPLLLGCMVMVVMWTWVRGTKLLNAKSRRDSISLQ
DLIHMLEKSKPTRVKGTAIFLTSTPETAPSAFMHNLKHNKVMHERVLIMSVQTEDMPRVAPANRYEIEQLSEDFTRVILH
YGYMESPRIPAALAILRKSGLKFDIMTTSFFLGRRSIKPAPNSSMPIWQDKLFIALSKQAANATDFFSIPSDRVVELGAQ
VTI
>Mature_642_residues
TQQIAQDQGSLDVSVPCPAPVPPHVQHEGFGGLVLGSIGVVYGDIGTSPLYALRESLKHVEEAGISDMSVIGTISLLLWA
LFFTVTAKYVLFLMQADNKGEGGILSLMALAQKALGHRAISVFFLGVAGAALFSGDAIITPAISVLSALEGLETVAPHLE
PYILPVTVVILVSVFWVQSHGTARVAAFFGPIMAVFFLVIGGLGLMHIADAPRVLQAFDPTHGLHFLFSHGMMGFMVLGS
VFLAVTGAEALYADMGHFGRKPIQYAWIFFILPALSLNYLGQGALLLSHPAAVENPFFLLAPPWALLPLVILATLATVIA
SQAVITGAFSLVRQAIQLGLLPRMLILHTSETQEGQIFIPRLNRLLLIGVLVLVFVFKNSSALASAYGIAVTCTMVVTTA
LAFVVVWKLWKWPLWGAIAFVSAFLVIDVAFLAANLLKIVDGGWVPLLLGCMVMVVMWTWVRGTKLLNAKSRRDSISLQD
LIHMLEKSKPTRVKGTAIFLTSTPETAPSAFMHNLKHNKVMHERVLIMSVQTEDMPRVAPANRYEIEQLSEDFTRVILHY
GYMESPRIPAALAILRKSGLKFDIMTTSFFLGRRSIKPAPNSSMPIWQDKLFIALSKQAANATDFFSIPSDRVVELGAQV
TI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=618, Percent_Identity=47.5728155339806, Blast_Score=575, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 69848; Mature: 69716

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQIAQDQGSLDVSVPCPAPVPPHVQHEGFGGLVLGSIGVVYGDIGTSPLYALRESLKH
CCCCHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHH
VEEAGISDMSVIGTISLLLWALFFTVTAKYVLFLMQADNKGEGGILSLMALAQKALGHRA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
ISVFFLGVAGAALFSGDAIITPAISVLSALEGLETVAPHLEPYILPVTVVILVSVFWVQS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
HGTARVAAFFGPIMAVFFLVIGGLGLMHIADAPRVLQAFDPTHGLHFLFSHGMMGFMVLG
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCCHHHHHHHCCHHHHHHHH
SVFLAVTGAEALYADMGHFGRKPIQYAWIFFILPALSLNYLGQGALLLSHPAAVENPFFL
HHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEE
LAPPWALLPLVILATLATVIASQAVITGAFSLVRQAIQLGLLPRMLILHTSETQEGQIFI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCCCEEEH
PRLNRLLLIGVLVLVFVFKNSSALASAYGIAVTCTMVVTTALAFVVVWKLWKWPLWGAIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FVSAFLVIDVAFLAANLLKIVDGGWVPLLLGCMVMVVMWTWVRGTKLLNAKSRRDSISLQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHH
DLIHMLEKSKPTRVKGTAIFLTSTPETAPSAFMHNLKHNKVMHERVLIMSVQTEDMPRVA
HHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
PANRYEIEQLSEDFTRVILHYGYMESPRIPAALAILRKSGLKFDIMTTSFFLGRRSIKPA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCC
PNSSMPIWQDKLFIALSKQAANATDFFSIPSDRVVELGAQVTI
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TQQIAQDQGSLDVSVPCPAPVPPHVQHEGFGGLVLGSIGVVYGDIGTSPLYALRESLKH
CCCHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCHHHHHHHHHHH
VEEAGISDMSVIGTISLLLWALFFTVTAKYVLFLMQADNKGEGGILSLMALAQKALGHRA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
ISVFFLGVAGAALFSGDAIITPAISVLSALEGLETVAPHLEPYILPVTVVILVSVFWVQS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
HGTARVAAFFGPIMAVFFLVIGGLGLMHIADAPRVLQAFDPTHGLHFLFSHGMMGFMVLG
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCCHHHHHHHCCHHHHHHHH
SVFLAVTGAEALYADMGHFGRKPIQYAWIFFILPALSLNYLGQGALLLSHPAAVENPFFL
HHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEE
LAPPWALLPLVILATLATVIASQAVITGAFSLVRQAIQLGLLPRMLILHTSETQEGQIFI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCCCEEEH
PRLNRLLLIGVLVLVFVFKNSSALASAYGIAVTCTMVVTTALAFVVVWKLWKWPLWGAIA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FVSAFLVIDVAFLAANLLKIVDGGWVPLLLGCMVMVVMWTWVRGTKLLNAKSRRDSISLQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHH
DLIHMLEKSKPTRVKGTAIFLTSTPETAPSAFMHNLKHNKVMHERVLIMSVQTEDMPRVA
HHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCC
PANRYEIEQLSEDFTRVILHYGYMESPRIPAALAILRKSGLKFDIMTTSFFLGRRSIKPA
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCC
PNSSMPIWQDKLFIALSKQAANATDFFSIPSDRVVELGAQVTI
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA