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The map label for this gene is qorA [H]

Identifier: 182678230

GI number: 182678230

Start: 1447583

End: 1448599

Strand: Direct

Name: qorA [H]

Synonym: Bind_1245

Alternate gene names: 182678230

Gene position: 1447583-1448599 (Clockwise)

Preceding gene: 182678229

Following gene: 182678232

Centisome position: 34.71

GC content: 57.13

Gene sequence:

>1017_bases
ATGGCCGCGATAATTCCCGACAGGATGCGCCAGATTTATTTCGACGGGAAGGGCGGTCCCGAGGTGATCCGTGTCGGCGA
GGCGGAGGTTCCGACGCCTGGTCGTGGTAAGGTCCTGATTGAGGTCGCGGCGGCGGGCATCAACCGGCCCGATTGTGTGC
AGCGCGCCGGATTCTATCCGCCGCCTCCCGGTGAAAGCGAGATCCCGGGTCTCGAAGTCGCTGGCAAAATCGTCAAGCTG
GGCGAGGGCGTGTCGCAATGGCAAATCGGCGATGAAGTCTGCGCTCTGCTCGGTTCTGGTGGTTATGCTGAATATGCCCT
TGCGGATGCGGCTTTGTGCCTGCCGGTGCCGAAGGGTCTGAGCCTGATTGAGGCTGCCGCTCTGCCGGAAACCTATTTCA
CCGTTTACGATAATGTATTCACGCGCGGCCGCTTGCAGCCGGGTGAAAATTTTCTCATCCATGGGGGTTCGAGCGGTATC
GGATCGACGGCGATTCAGCTTGCCAAGCAATTTGGTGCGAAGGTTTTCACGACAGCGGGTTCGGCCGAGAAATGCGCCTT
CTGCCGCACGCTCGGAGCCGACCATGCGATCGATTATAAAACCAGCGATTTCGTTGAGGAAATTCGCAAGATCACGGACA
ATAAATATCCGATCGATGTGATCCTCGACATGGTCGGTGGAAGTTATATCGCCAAAAACCTCTCGCTGCTGAATTTTGAT
GGACGCATGGTGCAGATCGCTTTTCTGCAATCGCCGAAAGTCGCGTCCTTCGATTTTCTGCCTCTCATGCTACGGCGCCT
CACCATGACCGGTTCGACCTTGCGGGCGCGGGCGCTCGGGCAAAAGATCGAAATCGCGGAAGCCTTGCGGGAGTTGGTCT
GGCCATTGCTCGATCAAGGCCTGGTCAAACCCATGGTTCATGCAACCTTTCCTCTAGAGGAAGCCCGGCAGTCGCATGAA
TTGATGGAATCCTCTGCCCATCTCGGCAAAATCCTCCTTGTGACGGGCTTAGCCTGA

Upstream 100 bases:

>100_bases
CGCGTCCTTGGGTTTCGGTTGAGAGAGGGGCTGGATCTTGCGAGTTCGTCATGAATGGACCAGAAAGGGGCACGGGGACA
TCGATCAAGGAGGATGATTC

Downstream 100 bases:

>100_bases
AAGTTTGATGTCTGTTGCGTCATCGAGCCTGTATACGATGAACCAAGGGTCACTCTCCGCGATCCTTGGTATCTGGGCAG
GAAAGCAGGCTTGACGCTAA

Product: PIG3 family NAD(P)H quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAAIIPDRMRQIYFDGKGGPEVIRVGEAEVPTPGRGKVLIEVAAAGINRPDCVQRAGFYPPPPGESEIPGLEVAGKIVKL
GEGVSQWQIGDEVCALLGSGGYAEYALADAALCLPVPKGLSLIEAAALPETYFTVYDNVFTRGRLQPGENFLIHGGSSGI
GSTAIQLAKQFGAKVFTTAGSAEKCAFCRTLGADHAIDYKTSDFVEEIRKITDNKYPIDVILDMVGGSYIAKNLSLLNFD
GRMVQIAFLQSPKVASFDFLPLMLRRLTMTGSTLRARALGQKIEIAEALRELVWPLLDQGLVKPMVHATFPLEEARQSHE
LMESSAHLGKILLVTGLA

Sequences:

>Translated_338_residues
MAAIIPDRMRQIYFDGKGGPEVIRVGEAEVPTPGRGKVLIEVAAAGINRPDCVQRAGFYPPPPGESEIPGLEVAGKIVKL
GEGVSQWQIGDEVCALLGSGGYAEYALADAALCLPVPKGLSLIEAAALPETYFTVYDNVFTRGRLQPGENFLIHGGSSGI
GSTAIQLAKQFGAKVFTTAGSAEKCAFCRTLGADHAIDYKTSDFVEEIRKITDNKYPIDVILDMVGGSYIAKNLSLLNFD
GRMVQIAFLQSPKVASFDFLPLMLRRLTMTGSTLRARALGQKIEIAEALRELVWPLLDQGLVKPMVHATFPLEEARQSHE
LMESSAHLGKILLVTGLA
>Mature_337_residues
AAIIPDRMRQIYFDGKGGPEVIRVGEAEVPTPGRGKVLIEVAAAGINRPDCVQRAGFYPPPPGESEIPGLEVAGKIVKLG
EGVSQWQIGDEVCALLGSGGYAEYALADAALCLPVPKGLSLIEAAALPETYFTVYDNVFTRGRLQPGENFLIHGGSSGIG
STAIQLAKQFGAKVFTTAGSAEKCAFCRTLGADHAIDYKTSDFVEEIRKITDNKYPIDVILDMVGGSYIAKNLSLLNFDG
RMVQIAFLQSPKVASFDFLPLMLRRLTMTGSTLRARALGQKIEIAEALRELVWPLLDQGLVKPMVHATFPLEEARQSHEL
MESSAHLGKILLVTGLA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=39.0909090909091, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=39.0909090909091, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=31.306990881459, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=31.306990881459, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=31.5286624203822, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=27.1137026239067, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI194239676, Length=329, Percent_Identity=27.9635258358663, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI28557745, Length=238, Percent_Identity=31.0924369747899, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI41872631, Length=312, Percent_Identity=27.2435897435897, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI47519420, Length=330, Percent_Identity=27.5757575757576, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=26.7676767676768, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1790485, Length=331, Percent_Identity=33.2326283987915, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI226510941, Length=332, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17507255, Length=336, Percent_Identity=28.2738095238095, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI212642053, Length=307, Percent_Identity=28.6644951140065, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=356, Percent_Identity=26.685393258427, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=243, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=341, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=360, Percent_Identity=26.3888888888889, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=360, Percent_Identity=26.1111111111111, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=363, Percent_Identity=25.3443526170799, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=26.0355029585799, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324195, Length=296, Percent_Identity=25.6756756756757, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920632, Length=273, Percent_Identity=25.2747252747253, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221330659, Length=273, Percent_Identity=25.2747252747253, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24581345, Length=275, Percent_Identity=26.5454545454545, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36360; Mature: 36228

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIIPDRMRQIYFDGKGGPEVIRVGEAEVPTPGRGKVLIEVAAAGINRPDCVQRAGFYP
CCCCCCCHHHEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCC
PPPGESEIPGLEVAGKIVKLGEGVSQWQIGDEVCALLGSGGYAEYALADAALCLPVPKGL
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCH
SLIEAAALPETYFTVYDNVFTRGRLQPGENFLIHGGSSGIGSTAIQLAKQFGAKVFTTAG
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCEEEEECC
SAEKCAFCRTLGADHAIDYKTSDFVEEIRKITDNKYPIDVILDMVGGSYIAKNLSLLNFD
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCEEEECC
GRMVQIAFLQSPKVASFDFLPLMLRRLTMTGSTLRARALGQKIEIAEALRELVWPLLDQG
CCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LVKPMVHATFPLEEARQSHELMESSAHLGKILLVTGLA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCC
>Mature Secondary Structure 
AAIIPDRMRQIYFDGKGGPEVIRVGEAEVPTPGRGKVLIEVAAAGINRPDCVQRAGFYP
CCCCCCHHHEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEEECCCCCCHHHHHCCCCC
PPPGESEIPGLEVAGKIVKLGEGVSQWQIGDEVCALLGSGGYAEYALADAALCLPVPKGL
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCH
SLIEAAALPETYFTVYDNVFTRGRLQPGENFLIHGGSSGIGSTAIQLAKQFGAKVFTTAG
HHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCEEEEECC
SAEKCAFCRTLGADHAIDYKTSDFVEEIRKITDNKYPIDVILDMVGGSYIAKNLSLLNFD
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCEEEECC
GRMVQIAFLQSPKVASFDFLPLMLRRLTMTGSTLRARALGQKIEIAEALRELVWPLLDQG
CCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LVKPMVHATFPLEEARQSHELMESSAHLGKILLVTGLA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]