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The map label for this gene is hypB [H]

Identifier: 182678145

GI number: 182678145

Start: 1341735

End: 1342676

Strand: Direct

Name: hypB [H]

Synonym: Bind_1160

Alternate gene names: 182678145

Gene position: 1341735-1342676 (Clockwise)

Preceding gene: 182678144

Following gene: 182678146

Centisome position: 32.17

GC content: 60.19

Gene sequence:

>942_bases
ATGTGCACGACTTGCGGCTGTGGCACCGGCGAGGTCAGGATCGAGGGCGAAGCCGGTCATCATCATGACCACGATCATGA
CCATCATGCTCATCACCATCATGGCCATACACATGATCATTCTCATGATCATGATCATGCGCCTCCAGAATCTCATGATC
ACACCCATGCCGATGGGGCCCTGGATTATGGCGCGGGCCCGGCGCGTTCGCATGCTCCAGGCCTCTCCCAGGCGCGGATG
ATCGAGATCGAGCAAGGCATACTCTCGAAGAATGATGGTCTCGCCGCGGGAAATCGCGCGCGGCTGCGCCAGGATGGTGT
TTTGGCGCTCAACCTTCTAGCGGGACCGGGCGCAGGTAAGACTACATTGCTGGTCGAAACTTTGCGGCGCCTTAAAAGCC
AGATCCCGGCGGCGGTGATCGAGGGTGATCAGCAGACCAGCCATGATGCCGAGCGAATCCGGGCAACCGGCGCGCCGGCC
ATTCAAGTCAATACCGGCAAGGGGTGCCATCTCGATGCCCATATGGTCGGCCATGCCATGGCGCATTTGCCCCTGAATAT
GGGTTCGGTGCTGTTTGTCGAGAATGTCGGCAATCTCGTTTGCCCGGCTGCCTTCGATCTCGGCGAGCGGCGGCGCGTCA
CCTTGCTCTCGGTCACCGAGGGGGAAGATAAACCGCTCAAATATCCGGATATTTTCGAAGGCGCGGATCTGGTACTTCTG
ACCAAAATCGATCTCCTGCCGCATCTCGATCTGGACCTTGCCGCATTGCGGGCCAATGTCGCGCGGATTGCGCCTAAAGC
CCAGGTGATCGCGCTTTCTACGCGCTCGGGTGAAGGCATGGAGGACTGGCTTGGCTGGTTGCGGGCGGAGCGACAGGCTT
TTCTCGCGGAATTGGCTGGTGAGGCCGAGGCACGCGCAGCGCTGCTACGGGCGGCGGAATAG

Upstream 100 bases:

>100_bases
CTTTAATGGATCGCCTGGACCCATGCCCGCGTTGCGGTGGAACTCGCCTGCATCCGACCGCGGGCACGGATGTCATGATC
AAGGATTTGGAGGTCATCTG

Downstream 100 bases:

>100_bases
GTTCTGATGAACGATCTTCCACCCATATTGGTCGTGGACGATGAACCACGCTCGGTGGAAGTGATGGCCCGTGTCCTGCG
CGAGGAATTCGACGTGCATG

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MCTTCGCGTGEVRIEGEAGHHHDHDHDHHAHHHHGHTHDHSHDHDHAPPESHDHTHADGALDYGAGPARSHAPGLSQARM
IEIEQGILSKNDGLAAGNRARLRQDGVLALNLLAGPGAGKTTLLVETLRRLKSQIPAAVIEGDQQTSHDAERIRATGAPA
IQVNTGKGCHLDAHMVGHAMAHLPLNMGSVLFVENVGNLVCPAAFDLGERRRVTLLSVTEGEDKPLKYPDIFEGADLVLL
TKIDLLPHLDLDLAALRANVARIAPKAQVIALSTRSGEGMEDWLGWLRAERQAFLAELAGEAEARAALLRAAE

Sequences:

>Translated_313_residues
MCTTCGCGTGEVRIEGEAGHHHDHDHDHHAHHHHGHTHDHSHDHDHAPPESHDHTHADGALDYGAGPARSHAPGLSQARM
IEIEQGILSKNDGLAAGNRARLRQDGVLALNLLAGPGAGKTTLLVETLRRLKSQIPAAVIEGDQQTSHDAERIRATGAPA
IQVNTGKGCHLDAHMVGHAMAHLPLNMGSVLFVENVGNLVCPAAFDLGERRRVTLLSVTEGEDKPLKYPDIFEGADLVLL
TKIDLLPHLDLDLAALRANVARIAPKAQVIALSTRSGEGMEDWLGWLRAERQAFLAELAGEAEARAALLRAAE
>Mature_313_residues
MCTTCGCGTGEVRIEGEAGHHHDHDHDHHAHHHHGHTHDHSHDHDHAPPESHDHTHADGALDYGAGPARSHAPGLSQARM
IEIEQGILSKNDGLAAGNRARLRQDGVLALNLLAGPGAGKTTLLVETLRRLKSQIPAAVIEGDQQTSHDAERIRATGAPA
IQVNTGKGCHLDAHMVGHAMAHLPLNMGSVLFVENVGNLVCPAAFDLGERRRVTLLSVTEGEDKPLKYPDIFEGADLVLL
TKIDLLPHLDLDLAALRANVARIAPKAQVIALSTRSGEGMEDWLGWLRAERQAFLAELAGEAEARAALLRAAE

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=293, Percent_Identity=53.9249146757679, Blast_Score=313, Evalue=8e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 33548; Mature: 33548

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTTCGCGTGEVRIEGEAGHHHDHDHDHHAHHHHGHTHDHSHDHDHAPPESHDHTHADGA
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LDYGAGPARSHAPGLSQARMIEIEQGILSKNDGLAAGNRARLRQDGVLALNLLAGPGAGK
CCCCCCCCCCCCCCCCCCEEEEEHHCHHCCCCCCCCCCHHHHCCCCEEEEEEEECCCCCC
TTLLVETLRRLKSQIPAAVIEGDQQTSHDAERIRATGAPAIQVNTGKGCHLDAHMVGHAM
HHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHH
AHLPLNMGSVLFVENVGNLVCPAAFDLGERRRVTLLSVTEGEDKPLKYPDIFEGADLVLL
HHCCCCCCCEEEEECCCCEECCHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEE
TKIDLLPHLDLDLAALRANVARIAPKAQVIALSTRSGEGMEDWLGWLRAERQAFLAELAG
EEEHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
EAEARAALLRAAE
CHHHHHHHHHCCC
>Mature Secondary Structure
MCTTCGCGTGEVRIEGEAGHHHDHDHDHHAHHHHGHTHDHSHDHDHAPPESHDHTHADGA
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LDYGAGPARSHAPGLSQARMIEIEQGILSKNDGLAAGNRARLRQDGVLALNLLAGPGAGK
CCCCCCCCCCCCCCCCCCEEEEEHHCHHCCCCCCCCCCHHHHCCCCEEEEEEEECCCCCC
TTLLVETLRRLKSQIPAAVIEGDQQTSHDAERIRATGAPAIQVNTGKGCHLDAHMVGHAM
HHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHH
AHLPLNMGSVLFVENVGNLVCPAAFDLGERRRVTLLSVTEGEDKPLKYPDIFEGADLVLL
HHCCCCCCCEEEEECCCCEECCHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEE
TKIDLLPHLDLDLAALRANVARIAPKAQVIALSTRSGEGMEDWLGWLRAERQAFLAELAG
EEEHHCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
EAEARAALLRAAE
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]