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The map label for this gene is hypA

Identifier: 182678144

GI number: 182678144

Start: 1341394

End: 1341735

Strand: Direct

Name: hypA

Synonym: Bind_1159

Alternate gene names: 182678144

Gene position: 1341394-1341735 (Clockwise)

Preceding gene: 182678143

Following gene: 182678145

Centisome position: 32.17

GC content: 58.77

Gene sequence:

>342_bases
ATGCATGAACTTTCCCTTTGCGAAAGCGTGATCGAGACGATCATGGACAATGTGCGGACTCATCATTTCAGTCAGGTGCG
GCGGGTACGGCTGACAGTCGGGCGTTTCGCGGGTGTTGAGACCGAGGCTTTGCGCTTTAGTTTTGATGTCGTGGCGCGTG
GCACGCTGGTCGAAGGTGCCGAGCTTGAGCTTCTGGAAGAGCCCGGCGCCGCCTGGTGCTTCGATTGCAGCGAGACCGTG
CCTTTAATGGATCGCCTGGACCCATGCCCGCGTTGCGGTGGAACTCGCCTGCATCCGACCGCGGGCACGGATGTCATGAT
CAAGGATTTGGAGGTCATCTGA

Upstream 100 bases:

>100_bases
CAACCTTGCCGACCGGGCCGCTACAAAGGCCCCTGGCGAGGCTGGTGCTCACCTCGATTAATCCTTGTGTCCCAGTCACC
TTGGCCGAGGCTTGAGAGAG

Downstream 100 bases:

>100_bases
TGTGCACGACTTGCGGCTGTGGCACCGGCGAGGTCAGGATCGAGGGCGAAGCCGGTCATCATCATGACCACGATCATGAC
CATCATGCTCATCACCATCA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGAELELLEEPGAAWCFDCSETV
PLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI

Sequences:

>Translated_113_residues
MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGAELELLEEPGAAWCFDCSETV
PLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI
>Mature_113_residues
MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGAELELLEEPGAAWCFDCSETV
PLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=40.1785714285714, Blast_Score=100, Evalue=3e-23,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=37.1681415929204, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_BEII9 (B2IJ38)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001832290.1
- GeneID:   6201294
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_1159
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- ProtClustDB:   CLSK979690
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12602; Mature: 12602

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCC
ELELLEEPGAAWCFDCSETVPLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI
CEEEECCCCCEEEECCCCCCCHHHCCCCCCCCCCCEECCCCCCCEEEECEECC
>Mature Secondary Structure
MHELSLCESVIETIMDNVRTHHFSQVRRVRLTVGRFAGVETEALRFSFDVVARGTLVEGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCC
ELELLEEPGAAWCFDCSETVPLMDRLDPCPRCGGTRLHPTAGTDVMIKDLEVI
CEEEECCCCCEEEECCCCCCCHHHCCCCCCCCCCCEECCCCCCCEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA