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The map label for this gene is pabC [H]

Identifier: 182678124

GI number: 182678124

Start: 1319973

End: 1320839

Strand: Direct

Name: pabC [H]

Synonym: Bind_1139

Alternate gene names: 182678124

Gene position: 1319973-1320839 (Clockwise)

Preceding gene: 182678123

Following gene: 182678125

Centisome position: 31.65

GC content: 59.63

Gene sequence:

>867_bases
ATGCCCCTGTTTTGGAGTGATGGCGCACTTTTCGAAACGGCGGTCCATCCCTACGATCTAACCGATCGCGGCTTGCTGCT
CGGTGACGGCCTGTTTGACACCGCTCTGGTCCTGCGGGGAAAGGTGCATCGCGAGATGGCGCACCGGATGCGGCTTTTGG
AGGGGCTCTCCGAGATCGGAATCGCGATGGCGCCGGAAATAATCATCGAGGCCTTCTCCGTTCTGGCCCATGCCAGCCGC
ACCAAAGGGATCGAACGGGCCGCCCTGCGCGTGATGATTACACGTGGCCCCGGTCCGCGCGGCCTCGGCCTGCCTCCCAC
GCCTTTGCCGCATCTTTTGGCCAGTCTCGCGCCGCTCGCTAACAATCCGTCCGCGCCATTGACCCTGCATGTCTCGAAGA
TCAGGCGCAACGAGACGTCGCCGCTGTCGCGTCTCAAAACCCTGTCGTCCCTCGACGCCGTGCTGGCTCATCGTGAGGCC
TTGAACGCCGGTTGCGACGAAGCTCTGTGCCTCAATACAGCGGGGCGGATCGCTTGCGCGGCCAGCGGTAATCTTTTCGC
GGTTTTTGGCCGTAAAATTCTCACCCCCAAGCTCGGCGAAGGGCTTTTGCCAGGCTGTATCCGTGCTCTCCTGCTCGCAG
AGGGCGCGTCCCTGGGCTATGAAATGATCGAAACAGAGTTGGAATGTGAGCATTTGCTTGCGGCCGAGGCTGTCTTCATG
ACCAATAGTCTGCGCCTGCTTGCGCCGGTTTCACGCATTGACGATGTGTCTTTTGTATCTGCTTCCCATGCGGCTTTCGC
CGCTTTGCGAGACTTTGTCTGGAGACATGCAGAGAATGAATGTGGTGTCGCTAATCATGATGTCTGA

Upstream 100 bases:

>100_bases
ATCTGGCCGCTGTTTGGCGTCCAGTTTCATCCAGAATCCGTCCTGACTCCTTGGGGAGACACAATTTTTCGCAATTTTTT
AAATGTGGTTGAGGCTTGGC

Downstream 100 bases:

>100_bases
GCCATGATCGAAGCTGCCCATTTCAAGCGATTGATCTTTCGCCATGGGCAATGGCCGCGCATGCTGCGCCAGAAAGTTTC
AGGTTTCGGCAAGGTGGCTG

Product: class IV aminotransferase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MPLFWSDGALFETAVHPYDLTDRGLLLGDGLFDTALVLRGKVHREMAHRMRLLEGLSEIGIAMAPEIIIEAFSVLAHASR
TKGIERAALRVMITRGPGPRGLGLPPTPLPHLLASLAPLANNPSAPLTLHVSKIRRNETSPLSRLKTLSSLDAVLAHREA
LNAGCDEALCLNTAGRIACAASGNLFAVFGRKILTPKLGEGLLPGCIRALLLAEGASLGYEMIETELECEHLLAAEAVFM
TNSLRLLAPVSRIDDVSFVSASHAAFAALRDFVWRHAENECGVANHDV

Sequences:

>Translated_288_residues
MPLFWSDGALFETAVHPYDLTDRGLLLGDGLFDTALVLRGKVHREMAHRMRLLEGLSEIGIAMAPEIIIEAFSVLAHASR
TKGIERAALRVMITRGPGPRGLGLPPTPLPHLLASLAPLANNPSAPLTLHVSKIRRNETSPLSRLKTLSSLDAVLAHREA
LNAGCDEALCLNTAGRIACAASGNLFAVFGRKILTPKLGEGLLPGCIRALLLAEGASLGYEMIETELECEHLLAAEAVFM
TNSLRLLAPVSRIDDVSFVSASHAAFAALRDFVWRHAENECGVANHDV
>Mature_287_residues
PLFWSDGALFETAVHPYDLTDRGLLLGDGLFDTALVLRGKVHREMAHRMRLLEGLSEIGIAMAPEIIIEAFSVLAHASRT
KGIERAALRVMITRGPGPRGLGLPPTPLPHLLASLAPLANNPSAPLTLHVSKIRRNETSPLSRLKTLSSLDAVLAHREAL
NAGCDEALCLNTAGRIACAASGNLFAVFGRKILTPKLGEGLLPGCIRALLLAEGASLGYEMIETELECEHLLAAEAVFMT
NSLRLLAPVSRIDDVSFVSASHAAFAALRDFVWRHAENECGVANHDV

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=257, Percent_Identity=30.3501945525292, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30898; Mature: 30767

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFWSDGALFETAVHPYDLTDRGLLLGDGLFDTALVLRGKVHREMAHRMRLLEGLSEIG
CCCEECCCCHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAMAPEIIIEAFSVLAHASRTKGIERAALRVMITRGPGPRGLGLPPTPLPHLLASLAPLA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
NNPSAPLTLHVSKIRRNETSPLSRLKTLSSLDAVLAHREALNAGCDEALCLNTAGRIACA
CCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEE
ASGNLFAVFGRKILTPKLGEGLLPGCIRALLLAEGASLGYEMIETELECEHLLAAEAVFM
CCCCEEEECCCHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TNSLRLLAPVSRIDDVSFVSASHAAFAALRDFVWRHAENECGVANHDV
HCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PLFWSDGALFETAVHPYDLTDRGLLLGDGLFDTALVLRGKVHREMAHRMRLLEGLSEIG
CCEECCCCHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAMAPEIIIEAFSVLAHASRTKGIERAALRVMITRGPGPRGLGLPPTPLPHLLASLAPLA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
NNPSAPLTLHVSKIRRNETSPLSRLKTLSSLDAVLAHREALNAGCDEALCLNTAGRIACA
CCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEE
ASGNLFAVFGRKILTPKLGEGLLPGCIRALLLAEGASLGYEMIETELECEHLLAAEAVFM
CCCCEEEECCCHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
TNSLRLLAPVSRIDDVSFVSASHAAFAALRDFVWRHAENECGVANHDV
HCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]