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The map label for this gene is pdxH [H]

Identifier: 182678093

GI number: 182678093

Start: 1276738

End: 1277364

Strand: Direct

Name: pdxH [H]

Synonym: Bind_1108

Alternate gene names: 182678093

Gene position: 1276738-1277364 (Clockwise)

Preceding gene: 182678090

Following gene: 182678095

Centisome position: 30.62

GC content: 59.01

Gene sequence:

>627_bases
GTGAATGAGTTAATGGGTCGTGACGTTCCGACAGCCACGCAATCGGACACGAATCCCTTCGAGACTTTTGCCGCCTGGTT
CGCCGAAGCCGAAAAAAGCGAAATCAACGATCCGAACGCCATGGCGCTCGCGACCGTCGACGCGTCGGGCTTGCCCGATG
TGCGGATGGTGCTGCTCAAGGCCTTCGACAGTACCGGATTCGTCTTTTACAGCAATGCCGAAAGCGCCAAGGGGCGCCAA
CTCGCCGGCAATATGCAGGCCGCTGCCGTATTGCATTGGAAATCCCTGCGCAGGCAGATTCGTTTTCGTGGGCCGGTCAG
TCAGGTGAGTACGGCGGAAGCAGATGCCTATTTCGCATCCCGTCCGTTGCAGAGCCGCATCGGGGCCTGGGCGAGCCAGC
AGTCACGTCCGCTCGAAAGCCGTTTCGCGCTTGAGACGGCGGTCGCTAAATTCACCGCCAAACATGCTCTGACACCTTTG
ACGAGACCGCCCTATTGGGTCGGTTATCGTATCGTGCCCCTCGCCATCGAATTCTGGTCCGATGGTGCTTTCCGGCTGCA
CGACCGTATTCGCTATTTCCGGCAGGCGGATACGGAACCCTGGAGTAAAGAGCGGCTCTATCCGTGA

Upstream 100 bases:

>100_bases
TGTCGTGGGACCATTGTGTCGTGCCTCCTTGCGGCAGCGTCCAGTCTTCACGGAATCAGGATGCCGGCCTGCAGCGGAGT
GATTAGCATGGGAGATTATC

Downstream 100 bases:

>100_bases
ATATTCATCCGTCGCGGGAAGGGAAGGACGAGGAGATGCGATGAAAGGGGATTAGAGGTGATGGGTCACCTCAGGTGAGT
CCCTATTTTTTCTTCCGGGC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MNELMGRDVPTATQSDTNPFETFAAWFAEAEKSEINDPNAMALATVDASGLPDVRMVLLKAFDSTGFVFYSNAESAKGRQ
LAGNMQAAAVLHWKSLRRQIRFRGPVSQVSTAEADAYFASRPLQSRIGAWASQQSRPLESRFALETAVAKFTAKHALTPL
TRPPYWVGYRIVPLAIEFWSDGAFRLHDRIRYFRQADTEPWSKERLYP

Sequences:

>Translated_208_residues
MNELMGRDVPTATQSDTNPFETFAAWFAEAEKSEINDPNAMALATVDASGLPDVRMVLLKAFDSTGFVFYSNAESAKGRQ
LAGNMQAAAVLHWKSLRRQIRFRGPVSQVSTAEADAYFASRPLQSRIGAWASQQSRPLESRFALETAVAKFTAKHALTPL
TRPPYWVGYRIVPLAIEFWSDGAFRLHDRIRYFRQADTEPWSKERLYP
>Mature_208_residues
MNELMGRDVPTATQSDTNPFETFAAWFAEAEKSEINDPNAMALATVDASGLPDVRMVLLKAFDSTGFVFYSNAESAKGRQ
LAGNMQAAAVLHWKSLRRQIRFRGPVSQVSTAEADAYFASRPLQSRIGAWASQQSRPLESRFALETAVAKFTAKHALTPL
TRPPYWVGYRIVPLAIEFWSDGAFRLHDRIRYFRQADTEPWSKERLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=205, Percent_Identity=39.5121951219512, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI1787926, Length=205, Percent_Identity=38.5365853658537, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553712, Length=211, Percent_Identity=39.8104265402844, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6319509, Length=199, Percent_Identity=39.1959798994975, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45551845, Length=186, Percent_Identity=40.8602150537634, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644901, Length=186, Percent_Identity=40.8602150537634, Blast_Score=121, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23437; Mature: 23437

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELMGRDVPTATQSDTNPFETFAAWFAEAEKSEINDPNAMALATVDASGLPDVRMVLLK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
AFDSTGFVFYSNAESAKGRQLAGNMQAAAVLHWKSLRRQIRFRGPVSQVSTAEADAYFAS
HHCCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
RPLQSRIGAWASQQSRPLESRFALETAVAKFTAKHALTPLTRPPYWVGYRIVPLAIEFWS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECEEEEEEEEEECC
DGAFRLHDRIRYFRQADTEPWSKERLYP
CCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNELMGRDVPTATQSDTNPFETFAAWFAEAEKSEINDPNAMALATVDASGLPDVRMVLLK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHH
AFDSTGFVFYSNAESAKGRQLAGNMQAAAVLHWKSLRRQIRFRGPVSQVSTAEADAYFAS
HHCCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
RPLQSRIGAWASQQSRPLESRFALETAVAKFTAKHALTPLTRPPYWVGYRIVPLAIEFWS
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECEEEEEEEEEECC
DGAFRLHDRIRYFRQADTEPWSKERLYP
CCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA