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The map label for this gene is argE [H]

Identifier: 182678026

GI number: 182678026

Start: 1192367

End: 1193545

Strand: Direct

Name: argE [H]

Synonym: Bind_1040

Alternate gene names: 182678026

Gene position: 1192367-1193545 (Clockwise)

Preceding gene: 182678025

Following gene: 182678028

Centisome position: 28.59

GC content: 58.86

Gene sequence:

>1179_bases
ATGGTGAATTCGCAAAATCCAGATGCCAGGCTGGGCGCTACGCTCGACATGCTTGAATGCCTTATCAGCTTTGACACGGA
GAGTTCGAAATCGAATCTGCCCCTCGTTGCGGCGGTCGAGGATTATCTTCGCGAACAAGCTGTTGACTATGTCAAAGTCC
CCAATGCGGAAGGGGATAAGGCCGCCCTTTTCATCAGCATTGGGCCGAAAGTGGATGGGGGCGTTGTCCTCTCCGGCCAT
ACGGATGTCGTGCCGGTTGAAGGGCAAAGCTGGACCAGCGACCCGTTTACCCTGCGCCGCGAGGCTGACCGTGTATTCGG
GCGCGGAACCTGTGACATGAAAGGTTTCGACGCCCTCTGTCTCGCCATGATTCCGGAATTCAAACAGGCGCGGCTGGCGC
GGCCGATCCATATTCTGCTGTCCTACGACGAGGAAATCGCCTGTACGGGCTCGCTGGATACGATTGCTCGTTTCGGTCAT
GATCTGCCACGTCCGGCGGCAGTGCTGGTGGGTGAACCAACCCTGATGCAAGTCGCCGACGCCCACAAAAGTGTCGCCAC
CTATCGCACGACTGTTCACGGTCACGAGGCGCATTCCTCGAAACCCTATCTCGGCGCCAGTGCTGTCGAAGCGGGCTGTG
ATCTCGTGACCGAGCTTTATCGTTTTGCCGAAGTTTTGGCCGCCGAAGGCGATCCGAGTGGCCGTTTCGATCCACCCGCC
TCGACCATTCATGTCGGCACGATTCATGGCGGTACGGCGCGCAATATCCTTGCGAAGGAATGCAGTTTCCTTTGGGAGTT
TCGTGGCCTGCCAGGCGTGGCGCAGGACCGTGCCTTGCGGCACCTTGAAGACTATGCCGCCCGTGTGGTTTTGCCGAAAA
TGACCCGTTATGCCCCCAAGGCGTCCATCGAGACTCTGGTCGAGGTGGAAGTTCCGGGGCTTGCTCCAGAAACGGGCTCG
CAAGCCGAGAGCCTGGCCTTGAAACTCGCGCGTTCCAATCGGACCATTACTGTGCCTTTCGCCACGGAAGCCGGCCAATT
TCAAAAGGCCGAAGTGCCGACCATCGTTTGCGGCCCGGGCTCGATCGACCAAGCGCATCAGCCGGATGAATATATTGCCA
TTGCCCAGATCGAGGCCGGCATTGCCTTCATGCGCCGGCTCGCGACCGAGATGGGTTGA

Upstream 100 bases:

>100_bases
AAGCAGCAATCCCCGTCTTTTCGCTCGATTCCCCATTCTCTCGACAAGTCCTAAACTGATCTTCGGATAAGAGCGGCGTC
TCGTCTCAACTGGATTGGCC

Downstream 100 bases:

>100_bases
TCTGCTCAGAACAGAAAATAGCGCTGCGCCATGGGCAGGCTCCTCGCTGGCTCGCAGGTCAGTACCATGCCATCAGCCTT
GACCACATAGGTTTCCGGAT

Product: acetylornithine deacetylase ArgE

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MVNSQNPDARLGATLDMLECLISFDTESSKSNLPLVAAVEDYLREQAVDYVKVPNAEGDKAALFISIGPKVDGGVVLSGH
TDVVPVEGQSWTSDPFTLRREADRVFGRGTCDMKGFDALCLAMIPEFKQARLARPIHILLSYDEEIACTGSLDTIARFGH
DLPRPAAVLVGEPTLMQVADAHKSVATYRTTVHGHEAHSSKPYLGASAVEAGCDLVTELYRFAEVLAAEGDPSGRFDPPA
STIHVGTIHGGTARNILAKECSFLWEFRGLPGVAQDRALRHLEDYAARVVLPKMTRYAPKASIETLVEVEVPGLAPETGS
QAESLALKLARSNRTITVPFATEAGQFQKAEVPTIVCGPGSIDQAHQPDEYIAIAQIEAGIAFMRRLATEMG

Sequences:

>Translated_392_residues
MVNSQNPDARLGATLDMLECLISFDTESSKSNLPLVAAVEDYLREQAVDYVKVPNAEGDKAALFISIGPKVDGGVVLSGH
TDVVPVEGQSWTSDPFTLRREADRVFGRGTCDMKGFDALCLAMIPEFKQARLARPIHILLSYDEEIACTGSLDTIARFGH
DLPRPAAVLVGEPTLMQVADAHKSVATYRTTVHGHEAHSSKPYLGASAVEAGCDLVTELYRFAEVLAAEGDPSGRFDPPA
STIHVGTIHGGTARNILAKECSFLWEFRGLPGVAQDRALRHLEDYAARVVLPKMTRYAPKASIETLVEVEVPGLAPETGS
QAESLALKLARSNRTITVPFATEAGQFQKAEVPTIVCGPGSIDQAHQPDEYIAIAQIEAGIAFMRRLATEMG
>Mature_392_residues
MVNSQNPDARLGATLDMLECLISFDTESSKSNLPLVAAVEDYLREQAVDYVKVPNAEGDKAALFISIGPKVDGGVVLSGH
TDVVPVEGQSWTSDPFTLRREADRVFGRGTCDMKGFDALCLAMIPEFKQARLARPIHILLSYDEEIACTGSLDTIARFGH
DLPRPAAVLVGEPTLMQVADAHKSVATYRTTVHGHEAHSSKPYLGASAVEAGCDLVTELYRFAEVLAAEGDPSGRFDPPA
STIHVGTIHGGTARNILAKECSFLWEFRGLPGVAQDRALRHLEDYAARVVLPKMTRYAPKASIETLVEVEVPGLAPETGS
QAESLALKLARSNRTITVPFATEAGQFQKAEVPTIVCGPGSIDQAHQPDEYIAIAQIEAGIAFMRRLATEMG

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=347, Percent_Identity=33.1412103746398, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788816, Length=207, Percent_Identity=28.5024154589372, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42210; Mature: 42210

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNSQNPDARLGATLDMLECLISFDTESSKSNLPLVAAVEDYLREQAVDYVKVPNAEGDK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHCCEEECCCCCCCC
AALFISIGPKVDGGVVLSGHTDVVPVEGQSWTSDPFTLRREADRVFGRGTCDMKGFDALC
EEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
LAMIPEFKQARLARPIHILLSYDEEIACTGSLDTIARFGHDLPRPAAVLVGEPTLMQVAD
HHHCCHHHHHHHCCCEEEEEECCCCEEECCCHHHHHHHCCCCCCCCEEEECCCHHHHHHH
AHKSVATYRTTVHGHEAHSSKPYLGASAVEAGCDLVTELYRFAEVLAAEGDPSGRFDPPA
HHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STIHVGTIHGGTARNILAKECSFLWEFRGLPGVAQDRALRHLEDYAARVVLPKMTRYAPK
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASIETLVEVEVPGLAPETGSQAESLALKLARSNRTITVPFATEAGQFQKAEVPTIVCGPG
CCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEECCC
SIDQAHQPDEYIAIAQIEAGIAFMRRLATEMG
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNSQNPDARLGATLDMLECLISFDTESSKSNLPLVAAVEDYLREQAVDYVKVPNAEGDK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHCCEEECCCCCCCC
AALFISIGPKVDGGVVLSGHTDVVPVEGQSWTSDPFTLRREADRVFGRGTCDMKGFDALC
EEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
LAMIPEFKQARLARPIHILLSYDEEIACTGSLDTIARFGHDLPRPAAVLVGEPTLMQVAD
HHHCCHHHHHHHCCCEEEEEECCCCEEECCCHHHHHHHCCCCCCCCEEEECCCHHHHHHH
AHKSVATYRTTVHGHEAHSSKPYLGASAVEAGCDLVTELYRFAEVLAAEGDPSGRFDPPA
HHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STIHVGTIHGGTARNILAKECSFLWEFRGLPGVAQDRALRHLEDYAARVVLPKMTRYAPK
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASIETLVEVEVPGLAPETGSQAESLALKLARSNRTITVPFATEAGQFQKAEVPTIVCGPG
CCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEECCC
SIDQAHQPDEYIAIAQIEAGIAFMRRLATEMG
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10692366 [H]