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The map label for this gene is oxlT [H]

Identifier: 182677973

GI number: 182677973

Start: 1130143

End: 1131813

Strand: Direct

Name: oxlT [H]

Synonym: Bind_0986

Alternate gene names: 182677973

Gene position: 1130143-1131813 (Clockwise)

Preceding gene: 182677972

Following gene: 182677975

Centisome position: 27.1

GC content: 57.21

Gene sequence:

>1671_bases
ATGAGAACGGCCTATCCTTCAGAGGAAGAAGTGACAACAGCAGGACCCTTGCAGCCGGATGTGAGCTATGGCCTGTTTGC
GCGCGAACGAATTGTCGCGGAACGCGGATTTAACCGTTGGCTGATCCCGCCCTGCGCCCTGGCCATCCATCTTTGTATTG
GCATGGCCTATGGTTTCAGTGTGTTCTGGTTGCCGTTGAGCCAGGCTCTTGGAATAGCAGCGCCTCTTGCCTGTCCTGAG
GAGATGAGTCTCTTGGGGCGGCTTTTCACGACCCAATGTGATTGGAAAATTGCTGATCTCGGCTGGATGTATACCCTGTT
TTTCGTTCTTCTCGGCTCGTCGGCGGCGCTCTTCGGTGGCTGGCTGGAAAAGGCGGGGCCGCGCAAGGCTGGCGTGATCG
CCGCTTTATGTTGGTGCGGTGGCCTCGTCGTCTCGGCGCTTGGAATCAAGCTGCATCAACTTTGGCTTTTATGGCTTGGC
TCCGGTGTCATTGGTGGCATCGGTCTTGGCCTTGGCTATATTTCGCCGGTTTCAACCTTGATCAAATGGTTTCCTGACCG
GCGCGGCATGGCGACGGGCATGGCAATCATGGGATTTGGTGGCGGTGCCATGATTGGTTCGCCACTGGCTGCCCTGTTAA
TGGCGCATTTCAGGACATCGGCCTCGGTCGGCGTCCTTGAAACTTTTCTTGTCATGGCGGGGATCTATTTCGTCTTCATG
ATGGTCGGGGCTTTCGGCTATCGTGTGCCCCCTTCAGGCTGGCAACCGGCGGGCTGGCAGTCTCCGGCCGGTACGAAGCG
GATGATCACCAACGGCCATGTGCATCTCAGTGAAGCGCATAAGACACCGCAATTCTGGTTGATCTGGGCTGTTCTCTGCC
TCAATGTTTCGGCAGGGATCGGCGTCATCGGCATGGCGTCTCCCATGCTGCAGGAAATTTTTGGCGGCAATCTCATTCAT
CGGCCGGATCTTGGTTTTGCCGCGCTCGATCCCGTGCAGCGTGGGGCCATCGCCGGCATTGCGGCGGGTTTCGCGGCTCT
TCTCTCGCTTTTCAATATTGGCGGCCGTTTCTTCTGGTCGACATTGTCGGACAAGATCGGCCGTAAAACAGCCTATCTGG
TGTTTTTTCTCCTTGGCATCATCCTCTATGCCGCTGCGCCGACATTTGCGCATATGGGGTCCAGGACTTTGTTCGTTGGT
GCCCTCTGCATTATCGTGTCGATGTATGGCGGTGGCTTCGCGCTGGCGCCGGCCTATCTTGCCGACATGTTCGGCACACA
ATTTGTCGGCGCCATCCATGGCCGTCTTTTGACAGCCTGGTCGACAGCCGGAATCATCGGCCCTGTCGTGGTCAATTATA
TTCGCGAGATCAATAAGGCGGCCGGTGTTCCTGACGACCGGCTCTATGATGTGACGCTCTATGTCCTGGCGGGCTTTCTC
GTTCTAGGCTTGCTCTGCAACGCTTTGATCAAGCCGGTGGCCGAGCATCGCTTCATGGACGTGGGAACAGGACCCGGCGC
CCATGAGACATCCGTCGCAGGCGATCTGTCTCACGGAATCGGGCGTGGTGGCCTGACGCCAACGGCTGCCCTGGCGTGGA
TGCTGGTTATTTTGCCGCTTCTCTGGGGTGTCGCGAAAACACTCGAAAGCGCAATCCGGCTTTTTCAATGA

Upstream 100 bases:

>100_bases
AGCATCGGTCCCGGAAGTGGTTGCTCCTTTCGGAATCGATGCGATAGCGCTGCGCGCCGGTATAAAGTTTGCTCAAGCAA
ACAAGGTCTTGGGAGGAATG

Downstream 100 bases:

>100_bases
AGCTATTCCAGCGGTCATCAACCATGACCGCTGGTCTCTCTATTATGAATGTCCTCCCGCGCCATAGAGCGTCTTGGCGA
GCTGCCGTGCTTCGGTGAAC

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MRTAYPSEEEVTTAGPLQPDVSYGLFARERIVAERGFNRWLIPPCALAIHLCIGMAYGFSVFWLPLSQALGIAAPLACPE
EMSLLGRLFTTQCDWKIADLGWMYTLFFVLLGSSAALFGGWLEKAGPRKAGVIAALCWCGGLVVSALGIKLHQLWLLWLG
SGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAMIGSPLAALLMAHFRTSASVGVLETFLVMAGIYFVFM
MVGAFGYRVPPSGWQPAGWQSPAGTKRMITNGHVHLSEAHKTPQFWLIWAVLCLNVSAGIGVIGMASPMLQEIFGGNLIH
RPDLGFAALDPVQRGAIAGIAAGFAALLSLFNIGGRFFWSTLSDKIGRKTAYLVFFLLGIILYAAAPTFAHMGSRTLFVG
ALCIIVSMYGGGFALAPAYLADMFGTQFVGAIHGRLLTAWSTAGIIGPVVVNYIREINKAAGVPDDRLYDVTLYVLAGFL
VLGLLCNALIKPVAEHRFMDVGTGPGAHETSVAGDLSHGIGRGGLTPTAALAWMLVILPLLWGVAKTLESAIRLFQ

Sequences:

>Translated_556_residues
MRTAYPSEEEVTTAGPLQPDVSYGLFARERIVAERGFNRWLIPPCALAIHLCIGMAYGFSVFWLPLSQALGIAAPLACPE
EMSLLGRLFTTQCDWKIADLGWMYTLFFVLLGSSAALFGGWLEKAGPRKAGVIAALCWCGGLVVSALGIKLHQLWLLWLG
SGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAMIGSPLAALLMAHFRTSASVGVLETFLVMAGIYFVFM
MVGAFGYRVPPSGWQPAGWQSPAGTKRMITNGHVHLSEAHKTPQFWLIWAVLCLNVSAGIGVIGMASPMLQEIFGGNLIH
RPDLGFAALDPVQRGAIAGIAAGFAALLSLFNIGGRFFWSTLSDKIGRKTAYLVFFLLGIILYAAAPTFAHMGSRTLFVG
ALCIIVSMYGGGFALAPAYLADMFGTQFVGAIHGRLLTAWSTAGIIGPVVVNYIREINKAAGVPDDRLYDVTLYVLAGFL
VLGLLCNALIKPVAEHRFMDVGTGPGAHETSVAGDLSHGIGRGGLTPTAALAWMLVILPLLWGVAKTLESAIRLFQ
>Mature_556_residues
MRTAYPSEEEVTTAGPLQPDVSYGLFARERIVAERGFNRWLIPPCALAIHLCIGMAYGFSVFWLPLSQALGIAAPLACPE
EMSLLGRLFTTQCDWKIADLGWMYTLFFVLLGSSAALFGGWLEKAGPRKAGVIAALCWCGGLVVSALGIKLHQLWLLWLG
SGVIGGIGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAMIGSPLAALLMAHFRTSASVGVLETFLVMAGIYFVFM
MVGAFGYRVPPSGWQPAGWQSPAGTKRMITNGHVHLSEAHKTPQFWLIWAVLCLNVSAGIGVIGMASPMLQEIFGGNLIH
RPDLGFAALDPVQRGAIAGIAAGFAALLSLFNIGGRFFWSTLSDKIGRKTAYLVFFLLGIILYAAAPTFAHMGSRTLFVG
ALCIIVSMYGGGFALAPAYLADMFGTQFVGAIHGRLLTAWSTAGIIGPVVVNYIREINKAAGVPDDRLYDVTLYVLAGFL
VLGLLCNALIKPVAEHRFMDVGTGPGAHETSVAGDLSHGIGRGGLTPTAALAWMLVILPLLWGVAKTLESAIRLFQ

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=393, Percent_Identity=23.4096692111959, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 59204; Mature: 59204

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]