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The map label for this gene is cysQ [H]

Identifier: 182677907

GI number: 182677907

Start: 1047926

End: 1048747

Strand: Direct

Name: cysQ [H]

Synonym: Bind_0915

Alternate gene names: 182677907

Gene position: 1047926-1048747 (Clockwise)

Preceding gene: 182677906

Following gene: 182677908

Centisome position: 25.13

GC content: 60.58

Gene sequence:

>822_bases
TTGGCCTCGCTCACTCATTCTGATGATCTCGTCGGCGCCTTTGCCGACATAGCTCGCGGAGCCGGGGATATTGCGCTTTC
CTATTTCAGGCCGGGAGAGCGCACACGCGCGGAAATTCAGCATAAGGTCGGCGGTTCTCCGGTCACAGAAGCGGATTATC
TTGTCGATCGCTTTCTGAAGGAACATCTCGCGAAATTATTGCCGGATGCCGGCTGGCTTTCTGAGGAAAGCGAGGATTCA
CCGGCGCGCCTTGGCAAAAAGCGGGTGGTGATCGTCGATCCGATCGATGGGACGCGCGGTTTCGCGCATGGCGATCCACG
CTGGGCGATCGCGATGGCCTTGGTTGAGGATCAAAGGCCCGTCGTCGGAATCGTCCATGCGCCGGCTCTCGGCGAAACCT
ATCTGGCCGTGGCAGGGCAAGGCGCGCGCTTGAACGACAAGCCCATCACGGTTTCGTCCCGCACCCATATGGACAAGGAT
GCCCGGATCGCGGCGCCCTTGCCGTTGGCCGAGCAATTACGTCAAGCCGGTCTGCCTTTCACGCTCGAACCGAAAATTCC
TTCCCTGGCCGTGCGCATTGCCAAGGTGGCTTCCGGGATCCTGGATGCGGGCTTTGCCACCGAAAATGCCAATGATTGGG
ATATTGCCGCTGCCGATCTCGTGTTGCATGAGGCTGGTGGACGGCTGGCCAGTCTCGAAGGATTGCCTTTGCTTTATAAT
CGGCCAGAGACGCGGCATGGTCTCCTGACGGCGGCGCCTGAGCGGATCCATGCGGAAGTCAATGCGGCGGCGCGCAGGGC
ACGGTCCAACCGGCTGGGTTGA

Upstream 100 bases:

>100_bases
CCGCGCGGATTCGTTGCGCCACCATGAAAAGCTTGTTTTCACTCAAGGAGGGGACTAAGCCTCATCCTACTTGTTTCTCC
TGTGGGTTTGATAATTTCCC

Downstream 100 bases:

>100_bases
CTTTTGCATCTTGGAGGGTTGAAGGGAAAGCGACTGAGCAGTTCGACTGTGCCAGTCCTCCCATTCCCCACTGATTTCCA
ACCGCGGACCAGCGCTGATG

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MASLTHSDDLVGAFADIARGAGDIALSYFRPGERTRAEIQHKVGGSPVTEADYLVDRFLKEHLAKLLPDAGWLSEESEDS
PARLGKKRVVIVDPIDGTRGFAHGDPRWAIAMALVEDQRPVVGIVHAPALGETYLAVAGQGARLNDKPITVSSRTHMDKD
ARIAAPLPLAEQLRQAGLPFTLEPKIPSLAVRIAKVASGILDAGFATENANDWDIAAADLVLHEAGGRLASLEGLPLLYN
RPETRHGLLTAAPERIHAEVNAAARRARSNRLG

Sequences:

>Translated_273_residues
MASLTHSDDLVGAFADIARGAGDIALSYFRPGERTRAEIQHKVGGSPVTEADYLVDRFLKEHLAKLLPDAGWLSEESEDS
PARLGKKRVVIVDPIDGTRGFAHGDPRWAIAMALVEDQRPVVGIVHAPALGETYLAVAGQGARLNDKPITVSSRTHMDKD
ARIAAPLPLAEQLRQAGLPFTLEPKIPSLAVRIAKVASGILDAGFATENANDWDIAAADLVLHEAGGRLASLEGLPLLYN
RPETRHGLLTAAPERIHAEVNAAARRARSNRLG
>Mature_272_residues
ASLTHSDDLVGAFADIARGAGDIALSYFRPGERTRAEIQHKVGGSPVTEADYLVDRFLKEHLAKLLPDAGWLSEESEDSP
ARLGKKRVVIVDPIDGTRGFAHGDPRWAIAMALVEDQRPVVGIVHAPALGETYLAVAGQGARLNDKPITVSSRTHMDKDA
RIAAPLPLAEQLRQAGLPFTLEPKIPSLAVRIAKVASGILDAGFATENANDWDIAAADLVLHEAGGRLASLEGLPLLYNR
PETRHGLLTAAPERIHAEVNAAARRARSNRLG

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=263, Percent_Identity=26.615969581749, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI221625487, Length=263, Percent_Identity=26.615969581749, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7657236, Length=203, Percent_Identity=29.064039408867, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1790659, Length=252, Percent_Identity=28.968253968254, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788882, Length=229, Percent_Identity=29.6943231441048, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=203, Percent_Identity=29.064039408867, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320493, Length=201, Percent_Identity=31.8407960199005, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24664918, Length=284, Percent_Identity=28.8732394366197, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357957, Length=233, Percent_Identity=29.1845493562232, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24664922, Length=235, Percent_Identity=30.6382978723404, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664926, Length=200, Percent_Identity=29.5, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357303, Length=225, Percent_Identity=28, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357329, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29235; Mature: 29103

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2 ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLTHSDDLVGAFADIARGAGDIALSYFRPGERTRAEIQHKVGGSPVTEADYLVDRFLK
CCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
EHLAKLLPDAGWLSEESEDSPARLGKKRVVIVDPIDGTRGFAHGDPRWAIAMALVEDQRP
HHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHCCCC
VVGIVHAPALGETYLAVAGQGARLNDKPITVSSRTHMDKDARIAAPLPLAEQLRQAGLPF
EEEEEECCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCEEECCCCHHHHHHHCCCCE
TLEPKIPSLAVRIAKVASGILDAGFATENANDWDIAAADLVLHEAGGRLASLEGLPLLYN
EECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCEEEC
RPETRHGLLTAAPERIHAEVNAAARRARSNRLG
CCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASLTHSDDLVGAFADIARGAGDIALSYFRPGERTRAEIQHKVGGSPVTEADYLVDRFLK
CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
EHLAKLLPDAGWLSEESEDSPARLGKKRVVIVDPIDGTRGFAHGDPRWAIAMALVEDQRP
HHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHCCCC
VVGIVHAPALGETYLAVAGQGARLNDKPITVSSRTHMDKDARIAAPLPLAEQLRQAGLPF
EEEEEECCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCEEECCCCHHHHHHHCCCCE
TLEPKIPSLAVRIAKVASGILDAGFATENANDWDIAAADLVLHEAGGRLASLEGLPLLYN
EECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCEEEC
RPETRHGLLTAAPERIHAEVNAAARRARSNRLG
CCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]