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The map label for this gene is degP [C]

Identifier: 182677790

GI number: 182677790

Start: 890259

End: 891239

Strand: Direct

Name: degP [C]

Synonym: Bind_0797

Alternate gene names: 182677790

Gene position: 890259-891239 (Clockwise)

Preceding gene: 182677789

Following gene: 182677791

Centisome position: 21.35

GC content: 59.43

Gene sequence:

>981_bases
ATGGTGCTCAAGGACGAAGACTGGAAAATTCCACCCGAGGCCCAGCCCAAACAAGGCAATTTTCGTTTCGATCTCGAACA
GACGATGAGTTCCATCGTCTCGATACGCTCACGTGTGCCGGCCGATGCCTTTACCGCCGGTATTTTGGGGACGGAACGGT
CCGGCAATGGCGTGCTGATCGACGCCGATGGTATTGTCCTGACGATCGGCTATCTCGTGACCGAAGCCGAGGAAGTCTGG
CTCACCACCAATGACGGTGTGGTCGTTGCCGGCCATGTGCTCGGCATTGATCCCGCGACGGGTTTCGCCCTTGTGCAAGC
GCTCGGCCGGCTGGAATTGCCCGTTATGCCGCTTGGGGAATCGCACAGCACAAGGGTCGGCGAGAGGGTGATCATTGGTG
GCGCTGGCGGTGTCGCGCATGCGCTCATCGCCCATATTGTCGCCAAACAGGAATTTGCCGGCTATTGGGAATATGTCCTC
GACGAGGCTTTGTTCACTGCTCCGGCGCATCCCGATTGGGGCGGCGCGGCCATGATCAGCGTGACCGGCAAGCTGCTCGG
CATCGGCTCCCTGCAAGTGCCGCATCAGGTTCATGGCGAACAGGTGCTGCAGCTCAATATGATGGTGCCGATCGATTTAT
TGGGACCGATCTACGCGGATCTGCGGATGTATGGTCGTCCCAATCGGCCACCGCGTCCTTGGCTCGGCCTGTTTGCCGCC
GAGGATCATGACAGGATCGTGGTCATTGGCTTTGCCGGTAATGGTCCAGCCAAGCGCGCGGGACTGAACGAGGGGGATAC
GATCCTGGCTGTCGCTGGCCATCCGGTCTCGACGCTCGTCGATTTGTTTCGGCATATCTGGGCCCTGGGGGCCGCCGGAT
GCGATGTTCCGCTCACGCTTGAACGGGAAGGGGATGTGTTTGAGGTTCATCTCACATCCGCCGATCGGGAGCGCTATCTG
AAATCGGCTTCAATGCATTAG

Upstream 100 bases:

>100_bases
CGACAGGAACGCGGCGTGCAGATAGAGTCTAGAATCGAGAAAAGCGCCCAGGATCACAACGGCGGATGATCAATGGGCCG
GTTCGATGGGGAGAGACCTC

Downstream 100 bases:

>100_bases
AATTTTAGCACTAGAATTTTGGGCATCATCCTTGCCTTATCGGCGAGGAGGACCACATCAGCTCTTTCATCCGTGCCGGA
AGGCGAGGAGAGGCGCGCCA

Product: PDZ/DHR/GLGF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MVLKDEDWKIPPEAQPKQGNFRFDLEQTMSSIVSIRSRVPADAFTAGILGTERSGNGVLIDADGIVLTIGYLVTEAEEVW
LTTNDGVVVAGHVLGIDPATGFALVQALGRLELPVMPLGESHSTRVGERVIIGGAGGVAHALIAHIVAKQEFAGYWEYVL
DEALFTAPAHPDWGGAAMISVTGKLLGIGSLQVPHQVHGEQVLQLNMMVPIDLLGPIYADLRMYGRPNRPPRPWLGLFAA
EDHDRIVVIGFAGNGPAKRAGLNEGDTILAVAGHPVSTLVDLFRHIWALGAAGCDVPLTLEREGDVFEVHLTSADRERYL
KSASMH

Sequences:

>Translated_326_residues
MVLKDEDWKIPPEAQPKQGNFRFDLEQTMSSIVSIRSRVPADAFTAGILGTERSGNGVLIDADGIVLTIGYLVTEAEEVW
LTTNDGVVVAGHVLGIDPATGFALVQALGRLELPVMPLGESHSTRVGERVIIGGAGGVAHALIAHIVAKQEFAGYWEYVL
DEALFTAPAHPDWGGAAMISVTGKLLGIGSLQVPHQVHGEQVLQLNMMVPIDLLGPIYADLRMYGRPNRPPRPWLGLFAA
EDHDRIVVIGFAGNGPAKRAGLNEGDTILAVAGHPVSTLVDLFRHIWALGAAGCDVPLTLEREGDVFEVHLTSADRERYL
KSASMH
>Mature_326_residues
MVLKDEDWKIPPEAQPKQGNFRFDLEQTMSSIVSIRSRVPADAFTAGILGTERSGNGVLIDADGIVLTIGYLVTEAEEVW
LTTNDGVVVAGHVLGIDPATGFALVQALGRLELPVMPLGESHSTRVGERVIIGGAGGVAHALIAHIVAKQEFAGYWEYVL
DEALFTAPAHPDWGGAAMISVTGKLLGIGSLQVPHQVHGEQVLQLNMMVPIDLLGPIYADLRMYGRPNRPPRPWLGLFAA
EDHDRIVVIGFAGNGPAKRAGLNEGDTILAVAGHPVSTLVDLFRHIWALGAAGCDVPLTLEREGDVFEVHLTSADRERYL
KSASMH

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786356, Length=277, Percent_Identity=24.187725631769, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789629, Length=274, Percent_Identity=25.9124087591241, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 34977; Mature: 34977

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKDEDWKIPPEAQPKQGNFRFDLEQTMSSIVSIRSRVPADAFTAGILGTERSGNGVLI
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEE
DADGIVLTIGYLVTEAEEVWLTTNDGVVVAGHVLGIDPATGFALVQALGRLELPVMPLGE
ECCCEEEEEEHHHCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCC
SHSTRVGERVIIGGAGGVAHALIAHIVAKQEFAGYWEYVLDEALFTAPAHPDWGGAAMIS
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
VTGKLLGIGSLQVPHQVHGEQVLQLNMMVPIDLLGPIYADLRMYGRPNRPPRPWLGLFAA
EEEEEEECCCCCCCHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
EDHDRIVVIGFAGNGPAKRAGLNEGDTILAVAGHPVSTLVDLFRHIWALGAAGCDVPLTL
CCCCEEEEEEECCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEE
EREGDVFEVHLTSADRERYLKSASMH
ECCCCEEEEEECCCHHHHHHHHCCCC
>Mature Secondary Structure
MVLKDEDWKIPPEAQPKQGNFRFDLEQTMSSIVSIRSRVPADAFTAGILGTERSGNGVLI
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEE
DADGIVLTIGYLVTEAEEVWLTTNDGVVVAGHVLGIDPATGFALVQALGRLELPVMPLGE
ECCCEEEEEEHHHCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCC
SHSTRVGERVIIGGAGGVAHALIAHIVAKQEFAGYWEYVLDEALFTAPAHPDWGGAAMIS
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
VTGKLLGIGSLQVPHQVHGEQVLQLNMMVPIDLLGPIYADLRMYGRPNRPPRPWLGLFAA
EEEEEEECCCCCCCHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
EDHDRIVVIGFAGNGPAKRAGLNEGDTILAVAGHPVSTLVDLFRHIWALGAAGCDVPLTL
CCCCEEEEEEECCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEE
EREGDVFEVHLTSADRERYLKSASMH
ECCCCEEEEEECCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA