Click here to switch to the map view.

The map label for this gene is yajO [H]

Identifier: 182677781

GI number: 182677781

Start: 881712

End: 882659

Strand: Direct

Name: yajO [H]

Synonym: Bind_0788

Alternate gene names: 182677781

Gene position: 881712-882659 (Clockwise)

Preceding gene: 182677779

Following gene: 182677785

Centisome position: 21.14

GC content: 57.81

Gene sequence:

>948_bases
ATGGAAAAACGCAAACTCGGCCGTTCAGGCCTGGAAATCGCCCCGCTTGTCCTTGGCGGCAATGTGTTCCGTTGGACGGC
CGATGCCAAGACCTCATATGCTCTGCTCGACACTTTCGTCGATCGCGGCTTCAATTGCGTCGATACGGCCGATGTCTATT
CGATTTGGGTCGATGGCCATCAAGGGGGAGAATCCGAAGGCATTATCGGCGATTGGCTGCAACAGACCGGCAAGCGCAAC
AAAATCGTGATCGCGACCAAGGTCGGCGGCGATATGCGCGGGTTCGGCAAGGGGCTTTCGAAGGAGCATATTCTGCGTTC
CGCCGAGGCTTCGTTGAAGCGTCTCAAGACGGATTACATCGATCTCTATCAGGCCCATTTCGATGATCCCGCGACACCGC
TCGAAGAGACTCTGGAGGCTTTCGACAGTCTCGTGAAAAGCGGCAAGGTGCGGGCGATCGGGGCGTCGAATTATGTTGCC
TCACGGCTCGATGAAGCCTTGAGCACTAGCCGCGCCAAGGGGTTCACGCCTTTCACCTGCCTGCAGCCGCATTACAATCT
CGTCAATCGCTCCCTGTTCGAAGGCGCGTTGCAGGAGCTTTGCCTCGCCGAAGGATTGGGTGTCATTCCCTATTATGCCT
TGGCGGCCGGTTTCCTCACCGGCAAATATCGCTCGACCAAGGATCTCGAAGGCAGTGCGCGGGCGGGTTCCGTCTATCAT
TATCTCGATCCGCGCGGCCTCGATATTCTGGCCGAGCTCGACAAGATCGCCGCGCGACTGAATGCCAGCGTGACGCAGAT
CTCACTTGCGTGGCTGCTTGCGCAAAAGGGTGTGACGGCGCCCATCGTGAGTGCGACGAGTTTGGCGCAGCTTGAGGATC
TGATGTGGTCCGTGGACATCAAGCTCGATAAGGAAGCGTTGCGGCGGCTTGATCTTGTGAGTGCGTGA

Upstream 100 bases:

>100_bases
AACTCTAAAGTTGCCGACGGCATCCCGAATATGCTGATTTATGCTGGGATAAAACCGCATGGCCTGAAACGACTCGGCCT
GTCTGGACGTGGGGTGATCG

Downstream 100 bases:

>100_bases
AGGGGCGTGCATACAGGGATATCGATGAACCCGTAGACAGCCGCCTGTTAGCGAGGATGTCACATCGCTCGAAGCCAAAG
GCTATGCTCCGAGGAAACAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEKRKLGRSGLEIAPLVLGGNVFRWTADAKTSYALLDTFVDRGFNCVDTADVYSIWVDGHQGGESEGIIGDWLQQTGKRN
KIVIATKVGGDMRGFGKGLSKEHILRSAEASLKRLKTDYIDLYQAHFDDPATPLEETLEAFDSLVKSGKVRAIGASNYVA
SRLDEALSTSRAKGFTPFTCLQPHYNLVNRSLFEGALQELCLAEGLGVIPYYALAAGFLTGKYRSTKDLEGSARAGSVYH
YLDPRGLDILAELDKIAARLNASVTQISLAWLLAQKGVTAPIVSATSLAQLEDLMWSVDIKLDKEALRRLDLVSA

Sequences:

>Translated_315_residues
MEKRKLGRSGLEIAPLVLGGNVFRWTADAKTSYALLDTFVDRGFNCVDTADVYSIWVDGHQGGESEGIIGDWLQQTGKRN
KIVIATKVGGDMRGFGKGLSKEHILRSAEASLKRLKTDYIDLYQAHFDDPATPLEETLEAFDSLVKSGKVRAIGASNYVA
SRLDEALSTSRAKGFTPFTCLQPHYNLVNRSLFEGALQELCLAEGLGVIPYYALAAGFLTGKYRSTKDLEGSARAGSVYH
YLDPRGLDILAELDKIAARLNASVTQISLAWLLAQKGVTAPIVSATSLAQLEDLMWSVDIKLDKEALRRLDLVSA
>Mature_315_residues
MEKRKLGRSGLEIAPLVLGGNVFRWTADAKTSYALLDTFVDRGFNCVDTADVYSIWVDGHQGGESEGIIGDWLQQTGKRN
KIVIATKVGGDMRGFGKGLSKEHILRSAEASLKRLKTDYIDLYQAHFDDPATPLEETLEAFDSLVKSGKVRAIGASNYVA
SRLDEALSTSRAKGFTPFTCLQPHYNLVNRSLFEGALQELCLAEGLGVIPYYALAAGFLTGKYRSTKDLEGSARAGSVYH
YLDPRGLDILAELDKIAARLNASVTQISLAWLLAQKGVTAPIVSATSLAQLEDLMWSVDIKLDKEALRRLDLVSA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=328, Percent_Identity=31.4024390243902, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4504825, Length=325, Percent_Identity=31.3846153846154, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=30.0613496932515, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI27436966, Length=326, Percent_Identity=30.0613496932515, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=30.0613496932515, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI27436971, Length=304, Percent_Identity=30.5921052631579, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI223718702, Length=297, Percent_Identity=30.3030303030303, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI41152114, Length=297, Percent_Identity=30.976430976431, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41327764, Length=275, Percent_Identity=30.5454545454545, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223718708, Length=160, Percent_Identity=33.75, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=36.25, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=30.6122448979592, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789375, Length=304, Percent_Identity=32.2368421052632, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=30.1829268292683, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788081, Length=282, Percent_Identity=28.0141843971631, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI48994888, Length=322, Percent_Identity=26.7080745341615, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786400, Length=292, Percent_Identity=26.3698630136986, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=30.0595238095238, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323998, Length=328, Percent_Identity=27.4390243902439, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=28.6184210526316, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=26.2536873156342, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=27.4900398406374, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=163, Percent_Identity=32.5153374233129, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=27.82874617737, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45549126, Length=327, Percent_Identity=27.82874617737, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24646155, Length=229, Percent_Identity=32.7510917030568, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646159, Length=236, Percent_Identity=28.8135593220339, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34377; Mature: 34377

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRKLGRSGLEIAPLVLGGNVFRWTADAKTSYALLDTFVDRGFNCVDTADVYSIWVDGH
CCCHHCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECC
QGGESEGIIGDWLQQTGKRNKIVIATKVGGDMRGFGKGLSKEHILRSAEASLKRLKTDYI
CCCCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DLYQAHFDDPATPLEETLEAFDSLVKSGKVRAIGASNYVASRLDEALSTSRAKGFTPFTC
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEE
LQPHYNLVNRSLFEGALQELCLAEGLGVIPYYALAAGFLTGKYRSTKDLEGSARAGSVYH
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
YLDPRGLDILAELDKIAARLNASVTQISLAWLLAQKGVTAPIVSATSLAQLEDLMWSVDI
ECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCE
KLDKEALRRLDLVSA
EECHHHHHHHHHCCC
>Mature Secondary Structure
MEKRKLGRSGLEIAPLVLGGNVFRWTADAKTSYALLDTFVDRGFNCVDTADVYSIWVDGH
CCCHHCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECC
QGGESEGIIGDWLQQTGKRNKIVIATKVGGDMRGFGKGLSKEHILRSAEASLKRLKTDYI
CCCCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DLYQAHFDDPATPLEETLEAFDSLVKSGKVRAIGASNYVASRLDEALSTSRAKGFTPFTC
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEE
LQPHYNLVNRSLFEGALQELCLAEGLGVIPYYALAAGFLTGKYRSTKDLEGSARAGSVYH
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
YLDPRGLDILAELDKIAARLNASVTQISLAWLLAQKGVTAPIVSATSLAQLEDLMWSVDI
ECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCE
KLDKEALRRLDLVSA
EECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]