Definition Beijerinckia indica subsp. indica ATCC 9039 chromosome, complete genome.
Accession NC_010581
Length 4,170,153

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The map label for this gene is murC

Identifier: 182677686

GI number: 182677686

Start: 775483

End: 776913

Strand: Direct

Name: murC

Synonym: Bind_0693

Alternate gene names: 182677686

Gene position: 775483-776913 (Clockwise)

Preceding gene: 182677685

Following gene: 182677687

Centisome position: 18.6

GC content: 59.47

Gene sequence:

>1431_bases
ATGAAATTGCCGCGCGAACTCGGCCCCATCCATTTCGTCGGGATTGGCGGCATCGGCATGTCCGGCATTGCCGAGGTCCT
GCTCAATCTTGGTTATCACGTCCAGGGATCCGACGCGGCGGAAAACGCCAATGTGTTGCGGCTGCGCACCAAAGGCGCGA
CGATCGCCATCGGCCATAAGCCTGAAAATCTGGGCGATGCGGCCGTGGTCGTGGTCTCGACCGCGATCAAGCGCGACAAT
CCGGAACTGGTCCATGCGCGTGAATTGCGTCTGCCGGTCGTGCGCCGCGCCGAAATGCTGGCCGAATTGATGCGGCTGAA
ACAATGTGTCGCGGTTGCCGGCACCCATGGCAAAACGACGACGACCTCGCTGGTCGCCACTTTGCTCGATGCGGGCAAAT
TCGATCCAACCGTTATCAATGGCGGGATTATCAATGCCTATGGCACCAATGCGCGGCTGGGCGCGGGCGACTGGATGGTG
GTCGAGGCCGATGAAAGCGACGGTACGTTCCTGAAACTGCCGGCCGATATTGCCATTGTCACGAATATCGATCCTGAACA
TCTCGATCATTTCAAGACTTTCGACGCCATCAAACAGGCGTTTCGCGCCTTTATTGAAAATATTCCCTTCTATGGTTTCG
CGGTCATGTGCCTCGATCATCCGGTGGTGCAGGAACTGGTCGGCACGATCGAGGATCGCCGGATCATCACCTATGGCGAG
AATCCGCAGGCAGACATGCGCCTCGTCGATGTCAATCTCGATGGCGGCATGTCACGTTTCAATGTCGTCGTGCGCGATCG
CAAGGCGGGGCAGGGGAAGCGCTTCGAGGAACGGCGTGTCGAGGATCTGCTCATGCCCATGCCGGGGCTGCATAATGCCT
TGAATGCGACGGCGGCTTTGAGTGTCGCCTTGCAGCTGGGCATGAGCGATGATGCGATCCGTTCGGCTTTGCGTGGTTTT
GGGGGCGTCAAGCGCCGCTTCACCCGCACCGGCGAATGGAATGGCGCGCAAATCTTCGATGATTACGGGCATCATCCGGT
GGAAATCGCGGCCGTTCTGCGCGCGGCGCGCGCCTCGACCAAAGGCCAGGTGATCGCCGTCGTGCAACCACATCGCTATA
CGCGCCTGCATTCCTTGTTCAATGAATTTGCAAGCTGCTTCAATGATGCCGACGTGGTGATCGTCGCCGATGTGTATGCG
GCGGGCGAACCGCCAATCGACGGCGCCGACAAGGAGCATTTGATGCGCGCCTTGAAAGCCTTCGGCCATCGCCAGGCCAT
GGTTCTCCGCGCACCGGAAGATCTCCCAGCACTCATCCGCAGCCTCGCGCATCCCGGTGACTATGTCGTGTGTTTAGGGG
CCGGCAATATTACGCAATGGGCCTATGCGCTTCCTGGTCAGCTTGCCGCGCCTGTCAGCAAGGCCTCCTGA

Upstream 100 bases:

>100_bases
CGGCCCGCAAGGCGGGGCTTCCCGATGCCGCCGAAAGGCTGGCTGATCTCGTTATCCGGTTTGCCTCAGGCGAAAAAACG
ATTCATGCAGGAGACAATCG

Downstream 100 bases:

>100_bases
AATGTTTGCCGATCTCATTCCGCGTCTGAGGGACGCCATGCCGGAATTGCGCGGTGAATTGCAGACCAATGTGCCGCTTG
CGCCCTGGACATGGTTCAAA

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKLPRELGPIHFVGIGGIGMSGIAEVLLNLGYHVQGSDAAENANVLRLRTKGATIAIGHKPENLGDAAVVVVSTAIKRDN
PELVHARELRLPVVRRAEMLAELMRLKQCVAVAGTHGKTTTTSLVATLLDAGKFDPTVINGGIINAYGTNARLGAGDWMV
VEADESDGTFLKLPADIAIVTNIDPEHLDHFKTFDAIKQAFRAFIENIPFYGFAVMCLDHPVVQELVGTIEDRRIITYGE
NPQADMRLVDVNLDGGMSRFNVVVRDRKAGQGKRFEERRVEDLLMPMPGLHNALNATAALSVALQLGMSDDAIRSALRGF
GGVKRRFTRTGEWNGAQIFDDYGHHPVEIAAVLRAARASTKGQVIAVVQPHRYTRLHSLFNEFASCFNDADVVIVADVYA
AGEPPIDGADKEHLMRALKAFGHRQAMVLRAPEDLPALIRSLAHPGDYVVCLGAGNITQWAYALPGQLAAPVSKAS

Sequences:

>Translated_476_residues
MKLPRELGPIHFVGIGGIGMSGIAEVLLNLGYHVQGSDAAENANVLRLRTKGATIAIGHKPENLGDAAVVVVSTAIKRDN
PELVHARELRLPVVRRAEMLAELMRLKQCVAVAGTHGKTTTTSLVATLLDAGKFDPTVINGGIINAYGTNARLGAGDWMV
VEADESDGTFLKLPADIAIVTNIDPEHLDHFKTFDAIKQAFRAFIENIPFYGFAVMCLDHPVVQELVGTIEDRRIITYGE
NPQADMRLVDVNLDGGMSRFNVVVRDRKAGQGKRFEERRVEDLLMPMPGLHNALNATAALSVALQLGMSDDAIRSALRGF
GGVKRRFTRTGEWNGAQIFDDYGHHPVEIAAVLRAARASTKGQVIAVVQPHRYTRLHSLFNEFASCFNDADVVIVADVYA
AGEPPIDGADKEHLMRALKAFGHRQAMVLRAPEDLPALIRSLAHPGDYVVCLGAGNITQWAYALPGQLAAPVSKAS
>Mature_476_residues
MKLPRELGPIHFVGIGGIGMSGIAEVLLNLGYHVQGSDAAENANVLRLRTKGATIAIGHKPENLGDAAVVVVSTAIKRDN
PELVHARELRLPVVRRAEMLAELMRLKQCVAVAGTHGKTTTTSLVATLLDAGKFDPTVINGGIINAYGTNARLGAGDWMV
VEADESDGTFLKLPADIAIVTNIDPEHLDHFKTFDAIKQAFRAFIENIPFYGFAVMCLDHPVVQELVGTIEDRRIITYGE
NPQADMRLVDVNLDGGMSRFNVVVRDRKAGQGKRFEERRVEDLLMPMPGLHNALNATAALSVALQLGMSDDAIRSALRGF
GGVKRRFTRTGEWNGAQIFDDYGHHPVEIAAVLRAARASTKGQVIAVVQPHRYTRLHSLFNEFASCFNDADVVIVADVYA
AGEPPIDGADKEHLMRALKAFGHRQAMVLRAPEDLPALIRSLAHPGDYVVCLGAGNITQWAYALPGQLAAPVSKAS

Specific function: Cell wall formation

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family

Homologues:

Organism=Escherichia coli, GI1786279, Length=471, Percent_Identity=45.0106157112527, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1790680, Length=401, Percent_Identity=27.431421446384, Blast_Score=138, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURC_BEII9 (B2IGG1)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831832.1
- ProteinModelPortal:   B2IGG1
- GeneID:   6199725
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0693
- HOGENOM:   HBG476594
- OMA:   YQPHRYS
- ProtClustDB:   PRK00421
- GO:   GO:0005737
- HAMAP:   MF_00046
- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758
- Gene3D:   G3DSA:3.90.190.20
- Gene3D:   G3DSA:3.40.1190.10
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR01082

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M; SSF53244 Mur_ligase_C; SSF53623 Mur_ligase_cen

EC number: =6.3.2.8

Molecular weight: Translated: 51521; Mature: 51521

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKLPRELGPIHFVGIGGIGMSGIAEVLLNLGYHVQGSDAAENANVLRLRTKGATIAIGHK
CCCCCHHCCEEEEEECCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEEECCCEEEECCC
PENLGDAAVVVVSTAIKRDNPELVHARELRLPVVRRAEMLAELMRLKQCVAVAGTHGKTT
CCCCCCCEEEEEHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TTSLVATLLDAGKFDPTVINGGIINAYGTNARLGAGDWMVVEADESDGTFLKLPADIAIV
HHHHHHHHHHCCCCCCEEEECCEEEECCCCCEECCCCEEEEEECCCCCCEEEECCCEEEE
TNIDPEHLDHFKTFDAIKQAFRAFIENIPFYGFAVMCLDHPVVQELVGTIEDRRIITYGE
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHCCHHHHHHHHHHCCCEEEEECC
NPQADMRLVDVNLDGGMSRFNVVVRDRKAGQGKRFEERRVEDLLMPMPGLHNALNATAAL
CCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
SVALQLGMSDDAIRSALRGFGGVKRRFTRTGEWNGAQIFDDYGHHPVEIAAVLRAARAST
HHHHHCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCC
KGQVIAVVQPHRYTRLHSLFNEFASCFNDADVVIVADVYAAGEPPIDGADKEHLMRALKA
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHH
FGHRQAMVLRAPEDLPALIRSLAHPGDYVVCLGAGNITQWAYALPGQLAAPVSKAS
CCCCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MKLPRELGPIHFVGIGGIGMSGIAEVLLNLGYHVQGSDAAENANVLRLRTKGATIAIGHK
CCCCCHHCCEEEEEECCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEEECCCEEEECCC
PENLGDAAVVVVSTAIKRDNPELVHARELRLPVVRRAEMLAELMRLKQCVAVAGTHGKTT
CCCCCCCEEEEEHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TTSLVATLLDAGKFDPTVINGGIINAYGTNARLGAGDWMVVEADESDGTFLKLPADIAIV
HHHHHHHHHHCCCCCCEEEECCEEEECCCCCEECCCCEEEEEECCCCCCEEEECCCEEEE
TNIDPEHLDHFKTFDAIKQAFRAFIENIPFYGFAVMCLDHPVVQELVGTIEDRRIITYGE
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHCCHHHHHHHHHHCCCEEEEECC
NPQADMRLVDVNLDGGMSRFNVVVRDRKAGQGKRFEERRVEDLLMPMPGLHNALNATAAL
CCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
SVALQLGMSDDAIRSALRGFGGVKRRFTRTGEWNGAQIFDDYGHHPVEIAAVLRAARAST
HHHHHCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHCCC
KGQVIAVVQPHRYTRLHSLFNEFASCFNDADVVIVADVYAAGEPPIDGADKEHLMRALKA
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHH
FGHRQAMVLRAPEDLPALIRSLAHPGDYVVCLGAGNITQWAYALPGQLAAPVSKAS
CCCCCEEEEECCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA