Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 182677684

GI number: 182677684

Start: 773220

End: 774362

Strand: Direct

Name: mrdB [H]

Synonym: Bind_0691

Alternate gene names: 182677684

Gene position: 773220-774362 (Clockwise)

Preceding gene: 182677683

Following gene: 182677685

Centisome position: 18.54

GC content: 60.37

Gene sequence:

>1143_bases
ATGATAAGCAGGGCAGAGCGTTCGCCTTTGGCCAATTGGTGGTGGACCGTCGATCGCTGGCTGCTGGCCAGCGTTTTGAT
GTTGATGGTGCTCGGCCTCGTATTGACCATGGCCGGCAGCCCGCCGGTCGCTGAAAGGCTCGGACTCTCGACCTTTCATT
TCGTGCATCGGCAGGTGCTCTATCTCATTCCGACGCTGGCCGTGCTGCTCGCCGCCTCCTTTCTCACGCCACGGCAGGTG
CGCCGCTCGGCCTTGATCATCTATGTCGTTTCGATGGCTTTGATCATCGCGGCGCTTCTCTTTGGTCATGAGGTCAAGGG
CGCGCGGCGCTGGATTTTCGGCATTCAGCCGTCGGAATTTTTGAAGCCTGCTTTCGTCATCCTCATCTCCTGGGCTTTTG
CCGAGGGTGGCACGCGCCGCGATGTGCCGGGCAATCTCATCGCGCTCATGCTTCTCCCCCTCACGATCATTCCCTTGATG
CTCCAGCCGGATTTCGGTCAGACCCTGCTCGTCTCGCTGGTCTGGGCGGCGCTCTTCTTCATGGCCGGTTTGCACTGGTT
CTGGGTCGTTGGCATTGGCGGCGCGGGCATCAGCGGCGGGCTGCTTGCCTATAAATTCGTGCCGCATGTGCGCGCCCGCG
TCTTGAAATTTCTCGACCCTGGCACGGGCGGCGGTATTGTTGACACGTTCCAGGTCGATACCGCCCTCGACAGCTTTCTC
TCCGGCGGCTGGTTCGGCAAGGGGCCGGGCGAGGGGACGGTCAAGCGCATTCTGCCGGACGCGCATACAGATTTCATTTT
CGCGGTGACGGGAGAGGAATTCGGCATTGCCGCCTGTCTCTTCATCGTCTCGATTTTCGCCTTCATCGTCTTGCGCGGTC
TGCTCTCCTCCTCCAGCAATGAGGACCCGTTCTGTCGTTTTGCCGCCGCCGGCCTCACAATGTTGTTCGGCATACAGAGC
GCCATCAATATGGCGGTGAACCTGCACCTGATGCCGGCCAAGGGGATGACCTTGCCGTTCATTTCCTATGGAGGGTCCTC
GCTGATTTCACTCGCCTTGGCGATCGGCTTTCTGATTGCCGTCTTGCGCAAGAGGCCGCGCTCGGCCGTGCTGCTCGAAC
AGGATGGGAAGGTTCTGGCGTGA

Upstream 100 bases:

>100_bases
AGTTTCGCGAGCTCGCCCGCGCCATCATCGGCCGGTCCGGTTGATCCGAACCTGCACAAACCCTTGATCCTCACCCTTCT
TCCGAGACGGAGGGCACAGC

Downstream 100 bases:

>100_bases
GCGATCTGCACCCTATTCTTGTCGCGGCTGGTGGCACCGGCGGGCATTTGTTTCCCGCGGAAGCCTTGAGCCGCGTGCTG
ATCAAGCGCGGCTTTCCGGT

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MISRAERSPLANWWWTVDRWLLASVLMLMVLGLVLTMAGSPPVAERLGLSTFHFVHRQVLYLIPTLAVLLAASFLTPRQV
RRSALIIYVVSMALIIAALLFGHEVKGARRWIFGIQPSEFLKPAFVILISWAFAEGGTRRDVPGNLIALMLLPLTIIPLM
LQPDFGQTLLVSLVWAALFFMAGLHWFWVVGIGGAGISGGLLAYKFVPHVRARVLKFLDPGTGGGIVDTFQVDTALDSFL
SGGWFGKGPGEGTVKRILPDAHTDFIFAVTGEEFGIAACLFIVSIFAFIVLRGLLSSSSNEDPFCRFAAAGLTMLFGIQS
AINMAVNLHLMPAKGMTLPFISYGGSSLISLALAIGFLIAVLRKRPRSAVLLEQDGKVLA

Sequences:

>Translated_380_residues
MISRAERSPLANWWWTVDRWLLASVLMLMVLGLVLTMAGSPPVAERLGLSTFHFVHRQVLYLIPTLAVLLAASFLTPRQV
RRSALIIYVVSMALIIAALLFGHEVKGARRWIFGIQPSEFLKPAFVILISWAFAEGGTRRDVPGNLIALMLLPLTIIPLM
LQPDFGQTLLVSLVWAALFFMAGLHWFWVVGIGGAGISGGLLAYKFVPHVRARVLKFLDPGTGGGIVDTFQVDTALDSFL
SGGWFGKGPGEGTVKRILPDAHTDFIFAVTGEEFGIAACLFIVSIFAFIVLRGLLSSSSNEDPFCRFAAAGLTMLFGIQS
AINMAVNLHLMPAKGMTLPFISYGGSSLISLALAIGFLIAVLRKRPRSAVLLEQDGKVLA
>Mature_380_residues
MISRAERSPLANWWWTVDRWLLASVLMLMVLGLVLTMAGSPPVAERLGLSTFHFVHRQVLYLIPTLAVLLAASFLTPRQV
RRSALIIYVVSMALIIAALLFGHEVKGARRWIFGIQPSEFLKPAFVILISWAFAEGGTRRDVPGNLIALMLLPLTIIPLM
LQPDFGQTLLVSLVWAALFFMAGLHWFWVVGIGGAGISGGLLAYKFVPHVRARVLKFLDPGTGGGIVDTFQVDTALDSFL
SGGWFGKGPGEGTVKRILPDAHTDFIFAVTGEEFGIAACLFIVSIFAFIVLRGLLSSSSNEDPFCRFAAAGLTMLFGIQS
AINMAVNLHLMPAKGMTLPFISYGGSSLISLALAIGFLIAVLRKRPRSAVLLEQDGKVLA

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=361, Percent_Identity=31.3019390581717, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786853, Length=328, Percent_Identity=29.2682926829268, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41224; Mature: 41224

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRAERSPLANWWWTVDRWLLASVLMLMVLGLVLTMAGSPPVAERLGLSTFHFVHRQVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHH
YLIPTLAVLLAASFLTPRQVRRSALIIYVVSMALIIAALLFGHEVKGARRWIFGIQPSEF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCHHHH
LKPAFVILISWAFAEGGTRRDVPGNLIALMLLPLTIIPLMLQPDFGQTLLVSLVWAALFF
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MAGLHWFWVVGIGGAGISGGLLAYKFVPHVRARVLKFLDPGTGGGIVDTFQVDTALDSFL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHH
SGGWFGKGPGEGTVKRILPDAHTDFIFAVTGEEFGIAACLFIVSIFAFIVLRGLLSSSSN
CCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EDPFCRFAAAGLTMLFGIQSAINMAVNLHLMPAKGMTLPFISYGGSSLISLALAIGFLIA
CCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHH
VLRKRPRSAVLLEQDGKVLA
HHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure
MISRAERSPLANWWWTVDRWLLASVLMLMVLGLVLTMAGSPPVAERLGLSTFHFVHRQVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHH
YLIPTLAVLLAASFLTPRQVRRSALIIYVVSMALIIAALLFGHEVKGARRWIFGIQPSEF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCHHHH
LKPAFVILISWAFAEGGTRRDVPGNLIALMLLPLTIIPLMLQPDFGQTLLVSLVWAALFF
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MAGLHWFWVVGIGGAGISGGLLAYKFVPHVRARVLKFLDPGTGGGIVDTFQVDTALDSFL
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHH
SGGWFGKGPGEGTVKRILPDAHTDFIFAVTGEEFGIAACLFIVSIFAFIVLRGLLSSSSN
CCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EDPFCRFAAAGLTMLFGIQSAINMAVNLHLMPAKGMTLPFISYGGSSLISLALAIGFLIA
CCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHH
VLRKRPRSAVLLEQDGKVLA
HHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]