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The map label for this gene is mraY

Identifier: 182677682

GI number: 182677682

Start: 770690

End: 771772

Strand: Direct

Name: mraY

Synonym: Bind_0689

Alternate gene names: 182677682

Gene position: 770690-771772 (Clockwise)

Preceding gene: 182677681

Following gene: 182677683

Centisome position: 18.48

GC content: 57.16

Gene sequence:

>1083_bases
ATGCTGACCTGGCTTGCCGAATTCGCGGTCTATTTCACACCGCTCAACCTGTTTCGCTATATCACCTTCCGGACCGGAGG
GGCGATCGCGACCGCTTTGTTCTTTGTGTTCTTCTTTGGTCCCAACATCATCAAATCGCTGCGCATCAAACAGGGTAAGG
GCCAGCCGATCCGGAGCGATGGACCACAATCGCATCTTCTGACCAAGAAGGGCACGCCCACCATGGGCGGCTTGATGATC
CTTTCGGGTCTCTTCGTCTCGACTTTGCTCTGGGCCAATCTATCCAATCATTATGTCTGGGTCGTGCTCTGGGTCATGCT
CGGTTATGGCGCCATCGGTTTTTATGATGATTATCTCAAGGTGACGAAACAGACCCACAACGGCTTTTCCGGCCGGGGGC
GTCTGGCCTGCGAGGCGGGGGTGGCGCTGGTCGCCTGCATCGCCATGATGAAACTGGGCACGCCGCATATGACCTCCCTC
GCTTTTCCGGCGGTCAATGGCTATGTCGTCGATCTCGGTCTCTTCTTTCTGATCTTCGGGCCTTTTGTGATCGTCGCCTC
GGGCAATGCGGTCAATCTGACCGATGGTCTCGACGGCCTCGCCATCGTGCCTGTGATGATCGCGGCGGGAACTTTCGGGA
TCATCGCCTATCTCGTTGGTAATGCCATCTACTCCGATTATCTGCGCATTAATTTCGTGCCCGGCGCCGGTGAACTCGCC
GTGGTCAGTGGCGCGGTCATCGGCGCAGGTCTCGGCTTTTTGTGGTTCAACGCGCCGCCCGCGCAGATTTTCATGGGCGA
TACCGGTTCATTGGCGCTCGGTGGCCTGCTTGGTACCATTGCCGTCGCGATCAAACATGAAATGGTGCTTGCCATTGTCG
GCGGCCTTTTCGCGCTCGAAACGCTTTCGGTCATTGTGCAGGTCGTGTCCTTTAAGCTGACCGGCAAGCGCGTCTTCAAA
ATGGCGCCGATCCATCATCATTTCGAACAACTCGGCTGGTCCGAGCCGCAGGTCGTGGTCCGTTTCTGGATCATTGCCTT
CGTGCTCGCGCTCGTCGGCCTTTCGACCTTGAAGCTGAGGTAG

Upstream 100 bases:

>100_bases
TCGCAGAGCCGGGCTGCTTTCCCAAAAAGCTGTTGGGGTTCAAAACGCATCAAACCAAAGCACCGGCTTTTGGATTTGAT
GCTCGGGGTTTTTGTAAACG

Downstream 100 bases:

>100_bases
GCATGACACCGGTCACAGCATTCAAGGGCAAGCGCCTTGCCTTGTTTGGTCTCGGCGGGTCGGGGCTCGTCAGTGCGCAA
GCGCTGAAAGCGGGCGGCGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLTWLAEFAVYFTPLNLFRYITFRTGGAIATALFFVFFFGPNIIKSLRIKQGKGQPIRSDGPQSHLLTKKGTPTMGGLMI
LSGLFVSTLLWANLSNHYVWVVLWVMLGYGAIGFYDDYLKVTKQTHNGFSGRGRLACEAGVALVACIAMMKLGTPHMTSL
AFPAVNGYVVDLGLFFLIFGPFVIVASGNAVNLTDGLDGLAIVPVMIAAGTFGIIAYLVGNAIYSDYLRINFVPGAGELA
VVSGAVIGAGLGFLWFNAPPAQIFMGDTGSLALGGLLGTIAVAIKHEMVLAIVGGLFALETLSVIVQVVSFKLTGKRVFK
MAPIHHHFEQLGWSEPQVVVRFWIIAFVLALVGLSTLKLR

Sequences:

>Translated_360_residues
MLTWLAEFAVYFTPLNLFRYITFRTGGAIATALFFVFFFGPNIIKSLRIKQGKGQPIRSDGPQSHLLTKKGTPTMGGLMI
LSGLFVSTLLWANLSNHYVWVVLWVMLGYGAIGFYDDYLKVTKQTHNGFSGRGRLACEAGVALVACIAMMKLGTPHMTSL
AFPAVNGYVVDLGLFFLIFGPFVIVASGNAVNLTDGLDGLAIVPVMIAAGTFGIIAYLVGNAIYSDYLRINFVPGAGELA
VVSGAVIGAGLGFLWFNAPPAQIFMGDTGSLALGGLLGTIAVAIKHEMVLAIVGGLFALETLSVIVQVVSFKLTGKRVFK
MAPIHHHFEQLGWSEPQVVVRFWIIAFVLALVGLSTLKLR
>Mature_360_residues
MLTWLAEFAVYFTPLNLFRYITFRTGGAIATALFFVFFFGPNIIKSLRIKQGKGQPIRSDGPQSHLLTKKGTPTMGGLMI
LSGLFVSTLLWANLSNHYVWVVLWVMLGYGAIGFYDDYLKVTKQTHNGFSGRGRLACEAGVALVACIAMMKLGTPHMTSL
AFPAVNGYVVDLGLFFLIFGPFVIVASGNAVNLTDGLDGLAIVPVMIAAGTFGIIAYLVGNAIYSDYLRINFVPGAGELA
VVSGAVIGAGLGFLWFNAPPAQIFMGDTGSLALGGLLGTIAVAIKHEMVLAIVGGLFALETLSVIVQVVSFKLTGKRVFK
MAPIHHHFEQLGWSEPQVVVRFWIIAFVLALVGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=363, Percent_Identity=53.168044077135, Blast_Score=351, Evalue=4e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BEII9 (B2IGF7)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001831828.1
- GeneID:   6201774
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_0689
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38700; Mature: 38700

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11d81d5c)-; HASH(0x1563b684)-; HASH(0x15518394)-; HASH(0x14a2efc4)-; HASH(0x1562a684)-; HASH(0x1563f1d8)-; HASH(0x156362a0)-; HASH(0x1563f0d0)-; HASH(0x1563939c)-; HASH(0x15242608)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTWLAEFAVYFTPLNLFRYITFRTGGAIATALFFVFFFGPNIIKSLRIKQGKGQPIRSD
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQSHLLTKKGTPTMGGLMILSGLFVSTLLWANLSNHYVWVVLWVMLGYGAIGFYDDYLK
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
VTKQTHNGFSGRGRLACEAGVALVACIAMMKLGTPHMTSLAFPAVNGYVVDLGLFFLIFG
HHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
PFVIVASGNAVNLTDGLDGLAIVPVMIAAGTFGIIAYLVGNAIYSDYLRINFVPGAGELA
HHHEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEE
VVSGAVIGAGLGFLWFNAPPAQIFMGDTGSLALGGLLGTIAVAIKHEMVLAIVGGLFALE
HHHHHHHHCCCHHEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVIVQVVSFKLTGKRVFKMAPIHHHFEQLGWSEPQVVVRFWIIAFVLALVGLSTLKLR
HHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHCCH
>Mature Secondary Structure
MLTWLAEFAVYFTPLNLFRYITFRTGGAIATALFFVFFFGPNIIKSLRIKQGKGQPIRSD
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQSHLLTKKGTPTMGGLMILSGLFVSTLLWANLSNHYVWVVLWVMLGYGAIGFYDDYLK
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
VTKQTHNGFSGRGRLACEAGVALVACIAMMKLGTPHMTSLAFPAVNGYVVDLGLFFLIFG
HHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHH
PFVIVASGNAVNLTDGLDGLAIVPVMIAAGTFGIIAYLVGNAIYSDYLRINFVPGAGELA
HHHEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEE
VVSGAVIGAGLGFLWFNAPPAQIFMGDTGSLALGGLLGTIAVAIKHEMVLAIVGGLFALE
HHHHHHHHCCCHHEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVIVQVVSFKLTGKRVFKMAPIHHHFEQLGWSEPQVVVRFWIIAFVLALVGLSTLKLR
HHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA