| Definition | Xylella fastidiosa M23 chromosome, complete genome. |
|---|---|
| Accession | NC_010577 |
| Length | 2,535,690 |
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The map label for this gene is pbpC [H]
Identifier: 182681898
GI number: 182681898
Start: 1509115
End: 1511499
Strand: Reverse
Name: pbpC [H]
Synonym: XfasM23_1366
Alternate gene names: 182681898
Gene position: 1511499-1509115 (Counterclockwise)
Preceding gene: 182681899
Following gene: 182681897
Centisome position: 59.61
GC content: 57.57
Gene sequence:
>2385_bases ATGTTCGTGCTTCCATCATTGTCGGCCTCCATGTTTGGTCGTTTGCGCGATGATCGTGCATTGACTTGGCTGCGCTGGAG TTGTGCTGGACTGCTTTCGCTGCTTCTTCTGTTGGATGTGCTTTGCCCATTGCCATTACCGACCTCGCACGATATGGCTT TGCTGGTGGTTGCTCGAGATGGTACTCCATTGCGTGCCTTCCCTGATGCTGATGGTGTATGGCGCTACCCGGCGCAGTTG GGACAGGTGTCGCCGTTGTATGTGCAGGCTCTGTTGACCTATGAGGACCGTATGTTCTGGCGCCATCCGGGGGTGAATCC TTGGGCGTTGTTACGTGCTGGGGGCCTGTGGCTGCGTTATGGTCATGTCGTTTCCGGTGGCTCGACGTTGACAATGCAGG CGGCACGGATTCTTGAGCCGCATGGCCGTACTCCTTGGGGCAAACTCAAGCAGTTGTTGCGTGCAGTACAGTTAGAAGTC CATTTGAGTAAGCGCCAGATTTTGCAGTTGTATTTGGAACGTGCCCCTTACGGAGGGACGATCCAGGGCGTTGAGGCGGC AAGCTGGGCTTATCTTGGCAAGTCGGCGGCACGCTTATCGCATGCTGAGGCGGCGTTGCTGGCGGTATTGCCGCAGTCGC CAAGCCGGTTGCGTCCGGACCGTAATCCGCAGTTGGCACGGCAAGCACGCGATAAGGTGCTGGCACGCATGGCAGTGCTT GGTGTCTGGTCTGATGAAGAGGTGAAAGATGCGCGGCTGGAGCCGGTGGTTGCACGTGCATTGCAGCCACCCATGTACGC GGCGTTGTTGGCGCAGCGTCTGCGTGTGCAACGGCCACATGCTGCACGCATTGTGACCACGTTGGACATTGATTTGCAGC GTACTCTTGAGGAAAGAGTGAGTACCTATTTCTCACCGTTACCTGAGCGCACTTCTGCTGCGGTGCTGGTGATGGATAAT CAAAGCCTGGAAGCACGTGCCTACGTTGGTTCGGTGACATTCGGTGATGCCAAGCGGTTGGGTCACGTGGATATGGTGCG GGCTTGGCGTTCGCCGGGTTCCACACTTAAACCGTTTCTTTATGGAATGGCGTTGGATCAGGGCTTGATTCATTCTGAGA GTTTGTTGGTCGATGCGCCACAGCATTTTGGTGATTATCGTCCGGGTAATTTCGATGCTGCGTTCACTGGCCCTATTGGT GCGTCCAGTGCATTGCGACAGTCGTTGAACGTGCCTGCAGTCGATTTGTTGGAACGGATTGGGCCGGCTCGGTTTGCGAC GCGTCTGGCGCATGCAGGGGTGCAGTTGCGTTTCCCACGCGGTGCCACCCCGAATTTGGCGTTGATCCTCGGGGGTGCAG GGGCACAGTTGCAGGAGCTGGTGGGTGCCTTCTCGGTGTTCAACCGCGGTGGCGTGGCAGGACGGGTGCGTTATACCCCG GAGGATCCGCGTATTGAGCGTCGTTTGATCTCCCCTGGTGCGGCTTGGATTGTGCGCGAGATTCTTGCTGCTAACCCGCG CCCTGGGTATGGCAGGGGCACGTTCGATACTGCGATGCGTCCGTCCGTGGCTTGGAAGACTGGTACCAGCTATGGCTTCC GTGATGCTTGGGCGCTGGGGAGTACCCGCCGCTACACAGTGGGTGTTTGGGTTGGGCGTCCGGATGGTACCCCGCTGCCG GGTCAGTATGGTGCGATTACGGCATTACCGTTGTTGTTTGATGTGATTGATGTGTTACCACGCGCGCCTGGTGATGCTGT GCCGGAGCCGATGCCAGCCAGTGTGGAGCAGGTTGATATCTGTTGGCCGCTGGGTTTTGCTGCTGCTAGCACGCCGCCGG AATTGTGCCGACGGCGCTACAGTGCCTACGTATTGGATGGGGTGGTGCCGCCGACCTTCGCTGAGCGTGATGCGAAATTG TGGCGTAGCGGTTTGGAACGATTCCAGGTCGATGTGCGTAGTGGTTTGCGTGTTAGGCCTGATTGTCGTCTGCCGCATCT GATCAGGGAGCAGCAGATTGCACGTTGGCCGACGTTGGTGATCCCATGGCTTGATGCTGTGGAGCGTCGTGCGACGCATC TGCCTCGGCTGGCCTCAGACTGTTCTGAGGATGATCGTGCTGATGCTGGGGTGCTGTACATTGATGGTCTCGTTGAAGGT GCCACATTGCAGCGTCCACCTGGTAGTACCAAGCCGGTACATCTGCAGTTGCGTGCATTGGGCAGTGAAACACGGATCGA CTGGCTCTTGGATGGGCGCTGGATTGCTCAAACTGTGGGGGGACAGACCTTTCAGCGTGATTTCCCAGAACCAGGGACGT ATATCTTGACTGCGTTGGCTGAGGATGGTGCTTGGAACAGGATGCAGTTCCGCGTTTTACGTTAA
Upstream 100 bases:
>100_bases GTGACCGAAGCGCATGATCGCTCGTTAACTTCCCATAAGGCTTTGATTTTATGAGATCTTGGCGGAGCAGGCACAATAGC CATCCCGTCCAGCAGTGAGT
Downstream 100 bases:
>100_bases GTAGGTGTGATGCAAAGTGTTTTCATTCCATCTCGGCAATGGGGGGAGGGAGTGCTCGTCTTTTGTTTCAATGTGTTGTT TCTTCCGCGCTTTGGTGAAT
Product: penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 794; Mature: 794
Protein sequence:
>794_residues MFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARDGTPLRAFPDADGVWRYPAQL GQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEV HLSKRQILQLYLERAPYGGTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMAVL GVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERVSTYFSPLPERTSAAVLVMDN QSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIG ASSALRQSLNVPAVDLLERIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRYTP EDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALGSTRRYTVGVWVGRPDGTPLP GQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKL WRSGLERFQVDVRSGLRVRPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLVEG ATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALAEDGAWNRMQFRVLR
Sequences:
>Translated_794_residues MFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARDGTPLRAFPDADGVWRYPAQL GQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEV HLSKRQILQLYLERAPYGGTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMAVL GVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERVSTYFSPLPERTSAAVLVMDN QSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIG ASSALRQSLNVPAVDLLERIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRYTP EDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALGSTRRYTVGVWVGRPDGTPLP GQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKL WRSGLERFQVDVRSGLRVRPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLVEG ATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALAEDGAWNRMQFRVLR >Mature_794_residues MFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARDGTPLRAFPDADGVWRYPAQL GQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRYGHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEV HLSKRQILQLYLERAPYGGTIQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMAVL GVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERVSTYFSPLPERTSAAVLVMDN QSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFLYGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIG ASSALRQSLNVPAVDLLERIGPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRYTP EDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALGSTRRYTVGVWVGRPDGTPLP GQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDICWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKL WRSGLERFQVDVRSGLRVRPDCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLVEG ATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALAEDGAWNRMQFRVLR
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=760, Percent_Identity=48.5526315789474, Blast_Score=651, Evalue=0.0, Organism=Escherichia coli, GI1786343, Length=590, Percent_Identity=26.9491525423729, Blast_Score=115, Evalue=9e-27, Organism=Escherichia coli, GI87082258, Length=303, Percent_Identity=30.3630363036304, Blast_Score=115, Evalue=1e-26, Organism=Escherichia coli, GI1789601, Length=178, Percent_Identity=30.8988764044944, Blast_Score=65, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 87711; Mature: 87711
Theoretical pI: Translated: 10.01; Mature: 10.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARD CEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC GTPLRAFPDADGVWRYPAQLGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRY CCCCEECCCCCCCEECHHHHCCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCEEEEE GHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEVHLSKRQILQLYLERAPYGGT CEEECCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC IQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMAVL CCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH GVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERV CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHH STYFSPLPERTSAAVLVMDNQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFL HHHHCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCHHHCCHHHHHHHHCCCCCHHHHHH YGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIGASSALRQSLNVPAVDLLERI HHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCCEECCCCCCHHHHHHHCCCCHHHHHHHH GPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRYTP CHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECC EDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALG CCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHHCC STRRYTVGVWVGRPDGTPLPGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDI CCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE CWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKLWRSGLERFQVDVRSGLRVRP EECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC DCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLVEG CCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCCCC ATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALA CEECCCCCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHCCCCCCCEEEEEEE EDGAWNRMQFRVLR CCCCCCCEEEEEEC >Mature Secondary Structure MFVLPSLSASMFGRLRDDRALTWLRWSCAGLLSLLLLLDVLCPLPLPTSHDMALLVVARD CEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC GTPLRAFPDADGVWRYPAQLGQVSPLYVQALLTYEDRMFWRHPGVNPWALLRAGGLWLRY CCCCEECCCCCCCEECHHHHCCCCHHHHHHHHHHHHHHEEECCCCCHHHHHHCCCEEEEE GHVVSGGSTLTMQAARILEPHGRTPWGKLKQLLRAVQLEVHLSKRQILQLYLERAPYGGT CEEECCCCEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC IQGVEAASWAYLGKSAARLSHAEAALLAVLPQSPSRLRPDRNPQLARQARDKVLARMAVL CCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHH GVWSDEEVKDARLEPVVARALQPPMYAALLAQRLRVQRPHAARIVTTLDIDLQRTLEERV CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHH STYFSPLPERTSAAVLVMDNQSLEARAYVGSVTFGDAKRLGHVDMVRAWRSPGSTLKPFL HHHHCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCHHHCCHHHHHHHHCCCCCHHHHHH YGMALDQGLIHSESLLVDAPQHFGDYRPGNFDAAFTGPIGASSALRQSLNVPAVDLLERI HHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCCEECCCCCCHHHHHHHCCCCHHHHHHHH GPARFATRLAHAGVQLRFPRGATPNLALILGGAGAQLQELVGAFSVFNRGGVAGRVRYTP CHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECC EDPRIERRLISPGAAWIVREILAANPRPGYGRGTFDTAMRPSVAWKTGTSYGFRDAWALG CCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHHCC STRRYTVGVWVGRPDGTPLPGQYGAITALPLLFDVIDVLPRAPGDAVPEPMPASVEQVDI CCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEE CWPLGFAAASTPPELCRRRYSAYVLDGVVPPTFAERDAKLWRSGLERFQVDVRSGLRVRP EECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC DCRLPHLIREQQIARWPTLVIPWLDAVERRATHLPRLASDCSEDDRADAGVLYIDGLVEG CCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEECCCCC ATLQRPPGSTKPVHLQLRALGSETRIDWLLDGRWIAQTVGGQTFQRDFPEPGTYILTALA CEECCCCCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHCCCHHHHCCCCCCCEEEEEEE EDGAWNRMQFRVLR CCCCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]