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The map label for this gene is ahpC [H]

Identifier: 182681334

GI number: 182681334

Start: 928755

End: 929315

Strand: Direct

Name: ahpC [H]

Synonym: XfasM23_0781

Alternate gene names: 182681334

Gene position: 928755-929315 (Clockwise)

Preceding gene: 182681333

Following gene: 182681335

Centisome position: 36.63

GC content: 46.35

Gene sequence:

>561_bases
ATGTCTGTTCTCAACACTGAAATACTTTCATTCAAAGCGACTGCTTACAAGAATGGCCAATTCGTTGAAGTTTCGGAGGC
GGTTTTCAAGGGAAAGTGGGCTGTGTTTGTTTTCTATCCTGCTGATTTTACTTTCGTCTGTCCGACTGAACTGGAAGATT
TGGCTGATCATTATGAGGAATTCCAGAAGTATGGGGTTGAGATATATTCGGTTTCCACAGACACGCATTTTTCACATAAG
GCTTGGCACGATATTTCACCAGCGATTGGCAAGATTAAGTATGCGATGATCGGTGATCCGACGCATGAGATCAGTCGGAA
TTTCAATGTGTTGCGCCCAAGTGGTTTGGCTGATCGCGGCACCTTCATCATTGATCCGCAGGGTGTGATTCAGTCGGTGG
AGATTACTGCTGAGGGCATTGGCCGTGATGCAAAAGAACTCTTGCGTAAGGTTAAAGCTGCGATTTATGTTGCCAATCAT
CCTGGCGAGGTTTGCCCAGCTAAGTGGGAAGAAGGCGGGAAAACTCTGGCACCGTCGTTGGATTTGGTCGGTAAAATCTG
A

Upstream 100 bases:

>100_bases
CGATTTAATTTATTCCATTGATTTGATAAATTAATAAGGGGTGCTTAAGCTATATATCATTCTGAGTTCTACACTTTCCG
CCACCAACAGGAAATACTCA

Downstream 100 bases:

>100_bases
ATTGCGAGACATCCTCGGCCAACAACGCGGTCGAGGATGATTTCATGAACTAAAAAGCTGGTACTCCGACGCGTCTGTTG
CGTCGCAGTTTTGTATGTGG

Product: peroxiredoxin

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVLNTEILSFKATAYKNGQFVEVSEAVFKGKWAVFVFYPADFTFVCPTELEDLADHYEEFQKYGVEIYSVSTDTHFSHK
AWHDISPAIGKIKYAMIGDPTHEISRNFNVLRPSGLADRGTFIIDPQGVIQSVEITAEGIGRDAKELLRKVKAAIYVANH
PGEVCPAKWEEGGKTLAPSLDLVGKI

Sequences:

>Translated_186_residues
MSVLNTEILSFKATAYKNGQFVEVSEAVFKGKWAVFVFYPADFTFVCPTELEDLADHYEEFQKYGVEIYSVSTDTHFSHK
AWHDISPAIGKIKYAMIGDPTHEISRNFNVLRPSGLADRGTFIIDPQGVIQSVEITAEGIGRDAKELLRKVKAAIYVANH
PGEVCPAKWEEGGKTLAPSLDLVGKI
>Mature_185_residues
SVLNTEILSFKATAYKNGQFVEVSEAVFKGKWAVFVFYPADFTFVCPTELEDLADHYEEFQKYGVEIYSVSTDTHFSHKA
WHDISPAIGKIKYAMIGDPTHEISRNFNVLRPSGLADRGTFIIDPQGVIQSVEITAEGIGRDAKELLRKVKAAIYVANHP
GEVCPAKWEEGGKTLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=47.3988439306358, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=47.3988439306358, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=41.7142857142857, Blast_Score=143, Evalue=8e-35,
Organism=Homo sapiens, GI4505591, Length=176, Percent_Identity=39.7727272727273, Blast_Score=140, Evalue=4e-34,
Organism=Homo sapiens, GI32455266, Length=176, Percent_Identity=39.7727272727273, Blast_Score=140, Evalue=4e-34,
Organism=Homo sapiens, GI32455264, Length=176, Percent_Identity=39.7727272727273, Blast_Score=140, Evalue=4e-34,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=40, Blast_Score=137, Evalue=5e-33,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=49.3506493506493, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=69.5187165775401, Blast_Score=287, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI32565831, Length=176, Percent_Identity=42.0454545454545, Blast_Score=139, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193204376, Length=176, Percent_Identity=42.0454545454545, Blast_Score=139, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=40.1129943502825, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323613, Length=176, Percent_Identity=38.0681818181818, Blast_Score=123, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320661, Length=174, Percent_Identity=36.2068965517241, Blast_Score=122, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319407, Length=158, Percent_Identity=28.4810126582279, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=40.1098901098901, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=40.1098901098901, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=39.5480225988701, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=36.1256544502618, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=32.2784810126582, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20641; Mature: 20509

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLNTEILSFKATAYKNGQFVEVSEAVFKGKWAVFVFYPADFTFVCPTELEDLADHYEE
CCCCCCHHHEEEEEEECCCCEEEHHHHHHCCCEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKYGVEIYSVSTDTHFSHKAWHDISPAIGKIKYAMIGDPTHEISRNFNVLRPSGLADRG
HHHCCEEEEEEECCCCCCCCCCCCCCCHHHHEEEEEECCCHHHHHCCCCEECCCCCCCCC
TFIIDPQGVIQSVEITAEGIGRDAKELLRKVKAAIYVANHPGEVCPAKWEEGGKTLAPSL
EEEECCHHHHEEEEEEHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEECCCC
DLVGKI
HHCCCC
>Mature Secondary Structure 
SVLNTEILSFKATAYKNGQFVEVSEAVFKGKWAVFVFYPADFTFVCPTELEDLADHYEE
CCCCCHHHEEEEEEECCCCEEEHHHHHHCCCEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKYGVEIYSVSTDTHFSHKAWHDISPAIGKIKYAMIGDPTHEISRNFNVLRPSGLADRG
HHHCCEEEEEEECCCCCCCCCCCCCCCHHHHEEEEEECCCHHHHHCCCCEECCCCCCCCC
TFIIDPQGVIQSVEITAEGIGRDAKELLRKVKAAIYVANHPGEVCPAKWEEGGKTLAPSL
EEEECCHHHHEEEEEEHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEECCCC
DLVGKI
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]