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The map label for this gene is gpsA

Identifier: 197294718

GI number: 197294718

Start: 691296

End: 692285

Strand: Reverse

Name: gpsA

Synonym: PAa_0684

Alternate gene names: 197294718

Gene position: 692285-691296 (Counterclockwise)

Preceding gene: 197294719

Following gene: 197294717

Centisome position: 78.67

GC content: 33.13

Gene sequence:

>990_bases
ATGCATATTACAATAATTGGCGGTGGAGCTTGGGGAGCAACTTTGGCTCAAGTTTTGACCGATAACAACCATCAAGTTTT
AGTTTATGATCTTAACAAAAATTATATTAATCGCATTAATCAAGGCATGCATTCTATTTTTGACCTTCCTTTAAAAAATA
TTCAATCAACTTCTGATTTAGAAATATCCTTGCTTTATTCTGATTTATTAGTTTTGGCGGTCCCTACAAAAGCTATGCGA
CAAGTTTTGCAACAGATTGCTTTATTATCTAAAACTCCTAAATCTTTTGTTAACGTTTCTAAAGGAATTGAACCGTCAAC
TTTTTTCCGCGTTTCTCAAATTGTGAATCAAATTATCCCTCCTTCTCTTTTGCAAAATTACGCTTCTTTGATGGGTCCTT
CTCACGCTGAAGAAGTTATATTAAGAAAAGTAACCCTTTTAACTGCTGCCTCTTCTGATTTATCTTTTGCCACCGAAATT
CAAAAAATTTTTTCTAACCCCATCTATTTAAAAATCTATACCTCTTCTGATTTGGTTGGTAATGAAGTTTGTAGTGCTTT
AAAAAATGTTTTGGCTTTAATTAATGGTATTTTAGTTGCTAAAGGGTTTGGAATCAATTCTCAAGCTGCCTTAATAAGTC
GTGGAATCGTTGAAATGTCTCGTTTAGTAACTTTTTATCATGGTAGTTTTAAAACAGTTTTGGGATTGCCTGGTTTAGGT
GATTTAATCGTGACTGCCTTTAGTACACATTCCAGAAACTTTTCAGCCGGTCAAAAAATTGGCGCTGGAAAAACTTATGA
ACAAATCATGTCTGAATCAGATCAAGTGATTGAAGGATTTCAAAGTCTTGTTGCTTTTTATCAATTGCAATCAAAACATC
AACTTGATTTGCCGCTTATTAAAGCCGCTTATCAATTGATTTATGAATGTAGGCCTTTTGAATTAGTTTTTGATGAATTA
ATGCAGAGACCTTTTAAGTCCGATTGTTAA

Upstream 100 bases:

>100_bases
GCGGAAAAGTAAAGTTATAGAAATACAAAAAGAGTTTAAAAAAATTATTTTTTTCTTTTTTTAAATATACAATATTTTTT
TTGGAAAGAATTTGAACATT

Downstream 100 bases:

>100_bases
AAAAAAGAAAAAAATGCAATAATTTTTTGTTTTTGCTTGCAATTTTTTTTTTTGATGTTATAATAATTACGTAATTTAAA
AGAAAGGAAAGAAAAAATGA

Product: Glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MHITIIGGGAWGATLAQVLTDNNHQVLVYDLNKNYINRINQGMHSIFDLPLKNIQSTSDLEISLLYSDLLVLAVPTKAMR
QVLQQIALLSKTPKSFVNVSKGIEPSTFFRVSQIVNQIIPPSLLQNYASLMGPSHAEEVILRKVTLLTAASSDLSFATEI
QKIFSNPIYLKIYTSSDLVGNEVCSALKNVLALINGILVAKGFGINSQAALISRGIVEMSRLVTFYHGSFKTVLGLPGLG
DLIVTAFSTHSRNFSAGQKIGAGKTYEQIMSESDQVIEGFQSLVAFYQLQSKHQLDLPLIKAAYQLIYECRPFELVFDEL
MQRPFKSDC

Sequences:

>Translated_329_residues
MHITIIGGGAWGATLAQVLTDNNHQVLVYDLNKNYINRINQGMHSIFDLPLKNIQSTSDLEISLLYSDLLVLAVPTKAMR
QVLQQIALLSKTPKSFVNVSKGIEPSTFFRVSQIVNQIIPPSLLQNYASLMGPSHAEEVILRKVTLLTAASSDLSFATEI
QKIFSNPIYLKIYTSSDLVGNEVCSALKNVLALINGILVAKGFGINSQAALISRGIVEMSRLVTFYHGSFKTVLGLPGLG
DLIVTAFSTHSRNFSAGQKIGAGKTYEQIMSESDQVIEGFQSLVAFYQLQSKHQLDLPLIKAAYQLIYECRPFELVFDEL
MQRPFKSDC
>Mature_329_residues
MHITIIGGGAWGATLAQVLTDNNHQVLVYDLNKNYINRINQGMHSIFDLPLKNIQSTSDLEISLLYSDLLVLAVPTKAMR
QVLQQIALLSKTPKSFVNVSKGIEPSTFFRVSQIVNQIIPPSLLQNYASLMGPSHAEEVILRKVTLLTAASSDLSFATEI
QKIFSNPIYLKIYTSSDLVGNEVCSALKNVLALINGILVAKGFGINSQAALISRGIVEMSRLVTFYHGSFKTVLGLPGLG
DLIVTAFSTHSRNFSAGQKIGAGKTYEQIMSESDQVIEGFQSLVAFYQLQSKHQLDLPLIKAAYQLIYECRPFELVFDEL
MQRPFKSDC

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=351, Percent_Identity=26.4957264957265, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI33695088, Length=349, Percent_Identity=25.5014326647564, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1790037, Length=312, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17507425, Length=277, Percent_Identity=25.9927797833935, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564399, Length=349, Percent_Identity=26.647564469914, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193210136, Length=359, Percent_Identity=25.9052924791086, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI32564403, Length=359, Percent_Identity=25.9052924791086, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=350, Percent_Identity=23.4285714285714, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17136200, Length=354, Percent_Identity=25.9887005649718, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17136202, Length=350, Percent_Identity=26, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17136204, Length=350, Percent_Identity=26, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI22026922, Length=351, Percent_Identity=23.9316239316239, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_PHYAS (B1VAP5)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001799259.1
- ProteinModelPortal:   B1VAP5
- SMR:   B1VAP5
- GeneID:   6799461
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   CLSK343695
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36292; Mature: 36292

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 188-188 BINDING 101-101 BINDING 101-101 BINDING 136-136 BINDING 252-252 BINDING 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHITIIGGGAWGATLAQVLTDNNHQVLVYDLNKNYINRINQGMHSIFDLPLKNIQSTSDL
CEEEEEECCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCCCC
EISLLYSDLLVLAVPTKAMRQVLQQIALLSKTPKSFVNVSKGIEPSTFFRVSQIVNQIIP
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCC
PSLLQNYASLMGPSHAEEVILRKVTLLTAASSDLSFATEIQKIFSNPIYLKIYTSSDLVG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCHH
NEVCSALKNVLALINGILVAKGFGINSQAALISRGIVEMSRLVTFYHGSFKTVLGLPGLG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHH
DLIVTAFSTHSRNFSAGQKIGAGKTYEQIMSESDQVIEGFQSLVAFYQLQSKHQLDLPLI
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KAAYQLIYECRPFELVFDELMQRPFKSDC
HHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHITIIGGGAWGATLAQVLTDNNHQVLVYDLNKNYINRINQGMHSIFDLPLKNIQSTSDL
CEEEEEECCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCCCC
EISLLYSDLLVLAVPTKAMRQVLQQIALLSKTPKSFVNVSKGIEPSTFFRVSQIVNQIIP
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCC
PSLLQNYASLMGPSHAEEVILRKVTLLTAASSDLSFATEIQKIFSNPIYLKIYTSSDLVG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCHH
NEVCSALKNVLALINGILVAKGFGINSQAALISRGIVEMSRLVTFYHGSFKTVLGLPGLG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHH
DLIVTAFSTHSRNFSAGQKIGAGKTYEQIMSESDQVIEGFQSLVAFYQLQSKHQLDLPLI
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KAAYQLIYECRPFELVFDELMQRPFKSDC
HHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA