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The map label for this gene is argS [H]

Identifier: 197294584

GI number: 197294584

Start: 540757

End: 542430

Strand: Direct

Name: argS [H]

Synonym: PAa_0540

Alternate gene names: 197294584

Gene position: 540757-542430 (Clockwise)

Preceding gene: 197294583

Following gene: 197294585

Centisome position: 61.45

GC content: 25.57

Gene sequence:

>1674_bases
ATGACTTTAGAAAATATCAAAATAAAAATAGAAAAAACTTTAAAAAAACTTTTAAATGAAGATGTTTTTTTGCAAGAACA
AGTTAATAATTATGATTTTGATTTTTCATTGCCTTTATTCGCTTATGCTAAAAAACAAAAATTGAATCCAGCTTTAATTT
TTAAGAATATCGAAAAAGAATTAATTAAAACTGAAGAAATAGAAGAAATAATGTTTTTAAATGGCTTTTTGAATATTAAA
TTAAAAAGAAAACTTGTAGCCAAAAATATTTTATTAGAAATAAATCGTCTTCAAAGTAATTACGGGGACCAACCAAACAA
AAATAAAACTGTAGTTATTGATTATTCTTCGCCTAATATTGCCAAAAATTTTTCTGTTGGTCATCTTCGTTCAACTGTTT
TAGGAAATGCCTTAAAAAACATTTATCAAAAATTAGGTTTTAAAGTGATTGGGATTAACCATTTAGGAGATTGGGGCACT
CAATTTGGAAAAATGATTGTTGCTTATCAAAAATGGGGTCAAAAAGAAAAAATTTTAAAAGATCCTATCAACGAACTCCA
AAAACTCTATCTTTTGTTTCATCAAAAAGCCGAGGAAAACCAAACATTAAACGATGAGGCCAACGAAGCCTTTTTACAAT
TAGAAAAAAAGAATAAAGAATATCTTGAGTTATGGAAGTATTTTCGCGATGTTTCTTTAAATGAATTTTGTAAAATTTAT
AAAATTCTCGGAGTTTCTTTTGATTATTTTTTAGGAGAGTCTTTTTATAACGATCAAATAAAAGAACTTTTAGAAGAATT
ACACCAAAAAAAACTTTTAAAACAAGAAGAAAAAATGTTGTTAATAGAATTAGATCAATTACCGCCTGGTTTAATTCAAA
AAACGAACGGCAGCACTTTATATTTAACTCGCGATTTGGCCACTCTTAAATATCGTTACAAAACTTACAATTGTCAAACT
ATTTTGTATGTAGTAGGAAACGAACAAAAACTTTATTTTAAACAATTGGATCAAATTATTAAAAAAATGGGATATCACGA
TGTTACAATTGAAAATATTAATTTTGGTTTGGTTTTGATGGATGGTAAAAAAATTTCAACAAGACATCATAAATTTACTA
CATTGATGGATGTTATTAATCAAGCAACAAACTTAGCCGAAAAAATTATTCAAGAAAAAAATCCGTCTTTAACTAACATC
AAAGAAACTGCTCAAAAAATCGCTGTTGGAGCTATTATTTTTAACGATCTTAAAAATGACAGGCATTTAGATATTGATTT
TAACCTTGAAAATATTTTACAATTCAAAGGACAAACAGCCCCTTATTTGCAATATACAGCCGCACGCCTTAATTCACTTT
TAAAAAAAGAAAAAATAGATTTTCAATTAATTGATGAAAACATATATCAACAAAATCATTATTTTGCTTTAATCAAATTA
TTAAGTCAATTTCCTTGGATTTTAGAAAAAAGCCAAAAAGAAAAAATGCCAAGTATTTTGTCTAGACATCTTATCAAAAT
AACTCAAAATGTTAATGGTTTATACGCTCAAGAAAGAATTTTATCTCACGATAAAATAATTAAAAACACTAATCTTTTAT
TAATTAAAGCAGTTTTAATTGTTATTAAAGAAAGTTTAAGAATTTTAGGAATTCCTTTTTTAGAAAGCATGTAA

Upstream 100 bases:

>100_bases
GAATTTTCCCAAAAATAAAAGGGAATGGAAACTGTTTTTCCTTCCAAAAAAAAGAATGGTTTTTGAAAAAATCATTTAGA
TTAATAAGGAAAGTAAAAAA

Downstream 100 bases:

>100_bases
ATTTGAGAATAAAAGTTTAAAACACAATACTTGCTTCTTTTTTTCCGTTATCACCAATTAATTTTGAATAAAGTTTAGAA
AATACACTTAATTTTTATTT

Product: Arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTLENIKIKIEKTLKKLLNEDVFLQEQVNNYDFDFSLPLFAYAKKQKLNPALIFKNIEKELIKTEEIEEIMFLNGFLNIK
LKRKLVAKNILLEINRLQSNYGDQPNKNKTVVIDYSSPNIAKNFSVGHLRSTVLGNALKNIYQKLGFKVIGINHLGDWGT
QFGKMIVAYQKWGQKEKILKDPINELQKLYLLFHQKAEENQTLNDEANEAFLQLEKKNKEYLELWKYFRDVSLNEFCKIY
KILGVSFDYFLGESFYNDQIKELLEELHQKKLLKQEEKMLLIELDQLPPGLIQKTNGSTLYLTRDLATLKYRYKTYNCQT
ILYVVGNEQKLYFKQLDQIIKKMGYHDVTIENINFGLVLMDGKKISTRHHKFTTLMDVINQATNLAEKIIQEKNPSLTNI
KETAQKIAVGAIIFNDLKNDRHLDIDFNLENILQFKGQTAPYLQYTAARLNSLLKKEKIDFQLIDENIYQQNHYFALIKL
LSQFPWILEKSQKEKMPSILSRHLIKITQNVNGLYAQERILSHDKIIKNTNLLLIKAVLIVIKESLRILGIPFLESM

Sequences:

>Translated_557_residues
MTLENIKIKIEKTLKKLLNEDVFLQEQVNNYDFDFSLPLFAYAKKQKLNPALIFKNIEKELIKTEEIEEIMFLNGFLNIK
LKRKLVAKNILLEINRLQSNYGDQPNKNKTVVIDYSSPNIAKNFSVGHLRSTVLGNALKNIYQKLGFKVIGINHLGDWGT
QFGKMIVAYQKWGQKEKILKDPINELQKLYLLFHQKAEENQTLNDEANEAFLQLEKKNKEYLELWKYFRDVSLNEFCKIY
KILGVSFDYFLGESFYNDQIKELLEELHQKKLLKQEEKMLLIELDQLPPGLIQKTNGSTLYLTRDLATLKYRYKTYNCQT
ILYVVGNEQKLYFKQLDQIIKKMGYHDVTIENINFGLVLMDGKKISTRHHKFTTLMDVINQATNLAEKIIQEKNPSLTNI
KETAQKIAVGAIIFNDLKNDRHLDIDFNLENILQFKGQTAPYLQYTAARLNSLLKKEKIDFQLIDENIYQQNHYFALIKL
LSQFPWILEKSQKEKMPSILSRHLIKITQNVNGLYAQERILSHDKIIKNTNLLLIKAVLIVIKESLRILGIPFLESM
>Mature_556_residues
TLENIKIKIEKTLKKLLNEDVFLQEQVNNYDFDFSLPLFAYAKKQKLNPALIFKNIEKELIKTEEIEEIMFLNGFLNIKL
KRKLVAKNILLEINRLQSNYGDQPNKNKTVVIDYSSPNIAKNFSVGHLRSTVLGNALKNIYQKLGFKVIGINHLGDWGTQ
FGKMIVAYQKWGQKEKILKDPINELQKLYLLFHQKAEENQTLNDEANEAFLQLEKKNKEYLELWKYFRDVSLNEFCKIYK
ILGVSFDYFLGESFYNDQIKELLEELHQKKLLKQEEKMLLIELDQLPPGLIQKTNGSTLYLTRDLATLKYRYKTYNCQTI
LYVVGNEQKLYFKQLDQIIKKMGYHDVTIENINFGLVLMDGKKISTRHHKFTTLMDVINQATNLAEKIIQEKNPSLTNIK
ETAQKIAVGAIIFNDLKNDRHLDIDFNLENILQFKGQTAPYLQYTAARLNSLLKKEKIDFQLIDENIYQQNHYFALIKLL
SQFPWILEKSQKEKMPSILSRHLIKITQNVNGLYAQERILSHDKIIKNTNLLLIKAVLIVIKESLRILGIPFLESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=500, Percent_Identity=33, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI15149476, Length=540, Percent_Identity=29.4444444444444, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1788184, Length=502, Percent_Identity=31.6733067729084, Blast_Score=253, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI71985061, Length=450, Percent_Identity=31.5555555555556, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI71985068, Length=450, Percent_Identity=31.5555555555556, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17532153, Length=491, Percent_Identity=28.3095723014257, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320548, Length=512, Percent_Identity=31.4453125, Blast_Score=267, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6321883, Length=582, Percent_Identity=30.2405498281787, Blast_Score=246, Evalue=5e-66,
Organism=Drosophila melanogaster, GI18859963, Length=510, Percent_Identity=29.4117647058824, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI28571570, Length=371, Percent_Identity=34.2318059299191, Blast_Score=188, Evalue=7e-48,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65211; Mature: 65080

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLENIKIKIEKTLKKLLNEDVFLQEQVNNYDFDFSLPLFAYAKKQKLNPALIFKNIEKE
CCCCCCEEEHHHHHHHHHCCCCEEHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LIKTEEIEEIMFLNGFLNIKLKRKLVAKNILLEINRLQSNYGDQPNKNKTVVIDYSSPNI
HHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
AKNFSVGHLRSTVLGNALKNIYQKLGFKVIGINHLGDWGTQFGKMIVAYQKWGQKEKILK
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHH
DPINELQKLYLLFHQKAEENQTLNDEANEAFLQLEKKNKEYLELWKYFRDVSLNEFCKIY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
KILGVSFDYFLGESFYNDQIKELLEELHQKKLLKQEEKMLLIELDQLPPGLIQKTNGSTL
HHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEECCCCEE
YLTRDLATLKYRYKTYNCQTILYVVGNEQKLYFKQLDQIIKKMGYHDVTIENINFGLVLM
EEEECHHHHEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECEEEEEEE
DGKKISTRHHKFTTLMDVINQATNLAEKIIQEKNPSLTNIKETAQKIAVGAIIFNDLKND
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RHLDIDFNLENILQFKGQTAPYLQYTAARLNSLLKKEKIDFQLIDENIYQQNHYFALIKL
CEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCHHHHHHHH
LSQFPWILEKSQKEKMPSILSRHLIKITQNVNGLYAQERILSHDKIIKNTNLLLIKAVLI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIKESLRILGIPFLESM
HHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
TLENIKIKIEKTLKKLLNEDVFLQEQVNNYDFDFSLPLFAYAKKQKLNPALIFKNIEKE
CCCCCEEEHHHHHHHHHCCCCEEHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LIKTEEIEEIMFLNGFLNIKLKRKLVAKNILLEINRLQSNYGDQPNKNKTVVIDYSSPNI
HHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
AKNFSVGHLRSTVLGNALKNIYQKLGFKVIGINHLGDWGTQFGKMIVAYQKWGQKEKILK
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHH
DPINELQKLYLLFHQKAEENQTLNDEANEAFLQLEKKNKEYLELWKYFRDVSLNEFCKIY
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHH
KILGVSFDYFLGESFYNDQIKELLEELHQKKLLKQEEKMLLIELDQLPPGLIQKTNGSTL
HHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEECCCCEE
YLTRDLATLKYRYKTYNCQTILYVVGNEQKLYFKQLDQIIKKMGYHDVTIENINFGLVLM
EEEECHHHHEEEEEEECCEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECEEEEEEE
DGKKISTRHHKFTTLMDVINQATNLAEKIIQEKNPSLTNIKETAQKIAVGAIIFNDLKND
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RHLDIDFNLENILQFKGQTAPYLQYTAARLNSLLKKEKIDFQLIDENIYQQNHYFALIKL
CEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCHHHHHHHH
LSQFPWILEKSQKEKMPSILSRHLIKITQNVNGLYAQERILSHDKIIKNTNLLLIKAVLI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIKESLRILGIPFLESM
HHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA