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The map label for this gene is cysS [H]

Identifier: 197294544

GI number: 197294544

Start: 494835

End: 496154

Strand: Direct

Name: cysS [H]

Synonym: PAa_0499

Alternate gene names: 197294544

Gene position: 494835-496154 (Clockwise)

Preceding gene: 197294543

Following gene: 197294545

Centisome position: 56.23

GC content: 25.76

Gene sequence:

>1320_bases
ATGTTAAAAATTTATAATTCCTTAACTAATCAAAAAGAAGATTTTATCCCTTTGTCTCCTCCTGATGTTAATATGTATGT
TTGTGGACCTACTGTTTACAATCATTTGCATTTGGGAAACGCAAGACCTTTAATTTTTTTTAATACAGTTAAAAAATATT
TAGAAACTATTGGTTTTAAAGTTTTTTATGTTGTTAATATTACCGATATTGATGATAAGATTATTAAATCTTCTTTGCAA
AAGCAAACAAAAGAAGAAGTTTTAGCGAAAGAATATATTTCATCTTTTTTACAATTATTAAAAGATTTAAATATTGAAAC
AATTAATTCTCATCCTAAAGCAACTAATTATATTCCTTCAATGATTGAATATATTAAAGTCCTTTTGGATAAAGGATTTG
CTTATTTTACTGATCAAGGAATTTATTTTGAAATATCTAAAATATCCGATTACGGCCAATTAAAAAACCAAGATTTAACT
CAATTAAAAAAAAATGCAAGAAAAACATTAGATCCTAATAAAAAAAAACCAGGTGATTTTGTTTTGTGGAAAAAAACTTC
CCAAGGTGTTCAATATCAAAGTCCATGGTTTTGTGGTAGGCCTGGATGGCATACCGAATGTGTTACCATGATTGAACAAA
TTTTTAAAACTTCATTAGATATTCACGGCGGTGGAGCTGATCTTAAGTTTCCTCATCATCAAAACGAAATTGCACAAGCA
AAAGCTTATAAGAATAATAATTTAGCAAATTTTTTTATGCATGTTGCCAGATTAGATTTTGAAAATCAAAAAATGTCTAA
ATCTTTAGGAAACATTGTATGGTGCAAAGATTTATTAAAAAGATTTAGTTCTTCTGTGATTAAGTTTTTTATTTTAAGTA
CTCATTATCGCAAACCCATTAATTTTTCTGAGAATCTAATAAAACAATCTCAAAAAAAATATGATAAAATTATGCTTTTT
TTGATTAAAAATGATTTTTATTTGCAAATCAAAAAAAAACCAATAGTGGATTTGGAACCAAAAATTATTGATTCTTTTCA
TCGACTGATGAAAGATGATTTTTCCACCAACAAAGTAATAGATTTAATTGAAATCAATATCAAAGAAGCTTATCAAAAAC
AGCAAGACCTAGATTTTTTAGCCAAAATACACAAATCTTTGTTATGGATTTTAGATGTTTTAGGAATTGAACCTCAGTTT
TTTCGTGCTGAAAAAAAAGATTTTGAAACTTATGTTAAATGGCAAGAAGCGAGACAAAATAAAGATTTTAAACAAGCAGA
TTTTTTAAGAAAAGAATTAATTGATAAAAATTTATTATAG

Upstream 100 bases:

>100_bases
TAAAGCCAAAAACCACAAAAAATAATTATTTTTTTAAATATATAATTTTATTTTTATACTTTTCTCAAGCTTTGTTTAAA
AATTAAAAAGGATTGTTGGA

Downstream 100 bases:

>100_bases
AAAGAGCTTTTTATGAATAATATCTTAACATCGAGAAAAGCTGTTAAAGTTTTTAAAAAAAATCATATTATTCCCCAAAA
TATTTTGGATCAAATTTTGA

Product: Cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MLKIYNSLTNQKEDFIPLSPPDVNMYVCGPTVYNHLHLGNARPLIFFNTVKKYLETIGFKVFYVVNITDIDDKIIKSSLQ
KQTKEEVLAKEYISSFLQLLKDLNIETINSHPKATNYIPSMIEYIKVLLDKGFAYFTDQGIYFEISKISDYGQLKNQDLT
QLKKNARKTLDPNKKKPGDFVLWKKTSQGVQYQSPWFCGRPGWHTECVTMIEQIFKTSLDIHGGGADLKFPHHQNEIAQA
KAYKNNNLANFFMHVARLDFENQKMSKSLGNIVWCKDLLKRFSSSVIKFFILSTHYRKPINFSENLIKQSQKKYDKIMLF
LIKNDFYLQIKKKPIVDLEPKIIDSFHRLMKDDFSTNKVIDLIEINIKEAYQKQQDLDFLAKIHKSLLWILDVLGIEPQF
FRAEKKDFETYVKWQEARQNKDFKQADFLRKELIDKNLL

Sequences:

>Translated_439_residues
MLKIYNSLTNQKEDFIPLSPPDVNMYVCGPTVYNHLHLGNARPLIFFNTVKKYLETIGFKVFYVVNITDIDDKIIKSSLQ
KQTKEEVLAKEYISSFLQLLKDLNIETINSHPKATNYIPSMIEYIKVLLDKGFAYFTDQGIYFEISKISDYGQLKNQDLT
QLKKNARKTLDPNKKKPGDFVLWKKTSQGVQYQSPWFCGRPGWHTECVTMIEQIFKTSLDIHGGGADLKFPHHQNEIAQA
KAYKNNNLANFFMHVARLDFENQKMSKSLGNIVWCKDLLKRFSSSVIKFFILSTHYRKPINFSENLIKQSQKKYDKIMLF
LIKNDFYLQIKKKPIVDLEPKIIDSFHRLMKDDFSTNKVIDLIEINIKEAYQKQQDLDFLAKIHKSLLWILDVLGIEPQF
FRAEKKDFETYVKWQEARQNKDFKQADFLRKELIDKNLL
>Mature_439_residues
MLKIYNSLTNQKEDFIPLSPPDVNMYVCGPTVYNHLHLGNARPLIFFNTVKKYLETIGFKVFYVVNITDIDDKIIKSSLQ
KQTKEEVLAKEYISSFLQLLKDLNIETINSHPKATNYIPSMIEYIKVLLDKGFAYFTDQGIYFEISKISDYGQLKNQDLT
QLKKNARKTLDPNKKKPGDFVLWKKTSQGVQYQSPWFCGRPGWHTECVTMIEQIFKTSLDIHGGGADLKFPHHQNEIAQA
KAYKNNNLANFFMHVARLDFENQKMSKSLGNIVWCKDLLKRFSSSVIKFFILSTHYRKPINFSENLIKQSQKKYDKIMLF
LIKNDFYLQIKKKPIVDLEPKIIDSFHRLMKDDFSTNKVIDLIEINIKEAYQKQQDLDFLAKIHKSLLWILDVLGIEPQF
FRAEKKDFETYVKWQEARQNKDFKQADFLRKELIDKNLL

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=376, Percent_Identity=34.5744680851064, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI21269877, Length=286, Percent_Identity=30.4195804195804, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI10835051, Length=286, Percent_Identity=30.4195804195804, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI303304987, Length=286, Percent_Identity=30.4195804195804, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI62240992, Length=286, Percent_Identity=30.4195804195804, Blast_Score=156, Evalue=4e-38,
Organism=Escherichia coli, GI1786737, Length=407, Percent_Identity=37.3464373464373, Blast_Score=286, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17509797, Length=358, Percent_Identity=29.0502793296089, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17509795, Length=358, Percent_Identity=29.0502793296089, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324082, Length=221, Percent_Identity=36.1990950226244, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19922218, Length=379, Percent_Identity=34.3007915567282, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI19922364, Length=292, Percent_Identity=29.4520547945205, Blast_Score=151, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51605; Mature: 51605

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIYNSLTNQKEDFIPLSPPDVNMYVCGPTVYNHLHLGNARPLIFFNTVKKYLETIGFK
CCCHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHEECCCCCCEEEHHHHHHHHHHHCCE
VFYVVNITDIDDKIIKSSLQKQTKEEVLAKEYISSFLQLLKDLNIETINSHPKATNYIPS
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHH
MIEYIKVLLDKGFAYFTDQGIYFEISKISDYGQLKNQDLTQLKKNARKTLDPNKKKPGDF
HHHHHHHHHHCCCCEEECCCEEEEEECCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCE
VLWKKTSQGVQYQSPWFCGRPGWHTECVTMIEQIFKTSLDIHGGGADLKFPHHQNEIAQA
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
KAYKNNNLANFFMHVARLDFENQKMSKSLGNIVWCKDLLKRFSSSVIKFFILSTHYRKPI
HHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NFSENLIKQSQKKYDKIMLFLIKNDFYLQIKKKPIVDLEPKIIDSFHRLMKDDFSTNKVI
CHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEE
DLIEINIKEAYQKQQDLDFLAKIHKSLLWILDVLGIEPQFFRAEKKDFETYVKWQEARQN
HHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
KDFKQADFLRKELIDKNLL
CCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKIYNSLTNQKEDFIPLSPPDVNMYVCGPTVYNHLHLGNARPLIFFNTVKKYLETIGFK
CCCHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHEECCCCCCEEEHHHHHHHHHHHCCE
VFYVVNITDIDDKIIKSSLQKQTKEEVLAKEYISSFLQLLKDLNIETINSHPKATNYIPS
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHH
MIEYIKVLLDKGFAYFTDQGIYFEISKISDYGQLKNQDLTQLKKNARKTLDPNKKKPGDF
HHHHHHHHHHCCCCEEECCCEEEEEECCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCE
VLWKKTSQGVQYQSPWFCGRPGWHTECVTMIEQIFKTSLDIHGGGADLKFPHHQNEIAQA
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
KAYKNNNLANFFMHVARLDFENQKMSKSLGNIVWCKDLLKRFSSSVIKFFILSTHYRKPI
HHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NFSENLIKQSQKKYDKIMLFLIKNDFYLQIKKKPIVDLEPKIIDSFHRLMKDDFSTNKVI
CHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEE
DLIEINIKEAYQKQQDLDFLAKIHKSLLWILDVLGIEPQFFRAEKKDFETYVKWQEARQN
HHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
KDFKQADFLRKELIDKNLL
CCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA