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The map label for this gene is thiJ [H]

Identifier: 197294540

GI number: 197294540

Start: 491679

End: 492221

Strand: Direct

Name: thiJ [H]

Synonym: PAa_0495

Alternate gene names: 197294540

Gene position: 491679-492221 (Clockwise)

Preceding gene: 197294539

Following gene: 197294541

Centisome position: 55.88

GC content: 30.76

Gene sequence:

>543_bases
ATGAAAGGACTATTAGTTTTATATGATGGTTTTGAAGATTGCGAAGCCTTAGTTACTAGAGCTTTGTTGAAACGCATCAA
TCTACCTTTAAATACTGCCACTCCCAATTCTTCATTAGAAGTTGTTTCTTCTAGTGGCCTTCAAGTCAAAGCAGATTATC
ATTTTTCTAAAATGGATCCATCTAATTATGATTTTTTAGTTATTCCAGGTGGACCTTATGTTGCTCAAATTATTGAAAAG
GAAACTTTTTTGTTGGAATTGATCCAGAAATTTGTTTTTTCTAATAAAATTATTGGAGCAATTTGTGCCGCTCCCATGTT
TTTAGGAAAATTAGATTTATTAAAGGAACATTCTTTTACTTGTTTTCCTAATTGCCAACATTTTATTTTGGGATCTTATT
TACCTGATAAAAAAGCTGTTATTAGTGGTAATTTTGTTACTTCTCGCTCTCCTATTACTGTTTTTGATTTTGTTTTTACT
TTGGTGGAGAAATTAAAAGGGGAATCAACTGCTTTAGCTTTTCAAAGATCTCTCAATGTTTAA

Upstream 100 bases:

>100_bases
AAAATTACTATTCAAAATATCGCAAAGCTATTTTTGTGGTATTTTTTTATTTTTTAAAATTTTTTCACCAAGATAAACAA
AATCAAAAAAAAGGAGTCTT

Downstream 100 bases:

>100_bases
AGTTCTTTATCAAGCAACAAATGCTTTTATTTTATAAAGAATTAATTTTTTAATTGTTCAAAAAAAACTTTTTTATTTAT
TTTGTTTGACTTAATCAATT

Product: Putative intracellular protease/amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKGLLVLYDGFEDCEALVTRALLKRINLPLNTATPNSSLEVVSSSGLQVKADYHFSKMDPSNYDFLVIPGGPYVAQIIEK
ETFLLELIQKFVFSNKIIGAICAAPMFLGKLDLLKEHSFTCFPNCQHFILGSYLPDKKAVISGNFVTSRSPITVFDFVFT
LVEKLKGESTALAFQRSLNV

Sequences:

>Translated_180_residues
MKGLLVLYDGFEDCEALVTRALLKRINLPLNTATPNSSLEVVSSSGLQVKADYHFSKMDPSNYDFLVIPGGPYVAQIIEK
ETFLLELIQKFVFSNKIIGAICAAPMFLGKLDLLKEHSFTCFPNCQHFILGSYLPDKKAVISGNFVTSRSPITVFDFVFT
LVEKLKGESTALAFQRSLNV
>Mature_180_residues
MKGLLVLYDGFEDCEALVTRALLKRINLPLNTATPNSSLEVVSSSGLQVKADYHFSKMDPSNYDFLVIPGGPYVAQIIEK
ETFLLELIQKFVFSNKIIGAICAAPMFLGKLDLLKEHSFTCFPNCQHFILGSYLPDKKAVISGNFVTSRSPITVFDFVFT
LVEKLKGESTALAFQRSLNV

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Escherichia coli, GI87081736, Length=173, Percent_Identity=31.2138728323699, Blast_Score=80, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17531319, Length=173, Percent_Identity=26.0115606936416, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17558714, Length=157, Percent_Identity=30.5732484076433, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571932, Length=177, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24653499, Length=178, Percent_Identity=27.5280898876405, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19978; Mature: 19978

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLLVLYDGFEDCEALVTRALLKRINLPLNTATPNSSLEVVSSSGLQVKADYHFSKMDP
CCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEECCCEECCCC
SNYDFLVIPGGPYVAQIIEKETFLLELIQKFVFSNKIIGAICAAPMFLGKLDLLKEHSFT
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCE
CFPNCQHFILGSYLPDKKAVISGNFVTSRSPITVFDFVFTLVEKLKGESTALAFQRSLNV
ECCCCCHHHHCCCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKGLLVLYDGFEDCEALVTRALLKRINLPLNTATPNSSLEVVSSSGLQVKADYHFSKMDP
CCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEECCCEECCCC
SNYDFLVIPGGPYVAQIIEKETFLLELIQKFVFSNKIIGAICAAPMFLGKLDLLKEHSFT
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCE
CFPNCQHFILGSYLPDKKAVISGNFVTSRSPITVFDFVFTLVEKLKGESTALAFQRSLNV
ECCCCCHHHHCCCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]