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The map label for this gene is holB [H]

Identifier: 197294305

GI number: 197294305

Start: 202245

End: 203192

Strand: Reverse

Name: holB [H]

Synonym: PAa_0168

Alternate gene names: 197294305

Gene position: 203192-202245 (Counterclockwise)

Preceding gene: 197294306

Following gene: 197294304

Centisome position: 23.09

GC content: 26.37

Gene sequence:

>948_bases
ATGCCAAACCAACCATTTTTAAAACCATTCTTAAAAATAATTCAAAACAAAAAATTAGCTCACCTTTATTTAATAACCGG
GCTTGATCTCCCTCAAAGAAAAAAATTTGTTTTGGAATTATCTTATCAAATTTTGAAATCCCAAGAAAATACTCAAAACC
ATTCTTTTTTAAAACAAACTTTAACTGAAGGCACATATCCTAACTTTTATTATTTAAAAAAAGATAACCATCTTTTTAAA
AAAGAGCAAATATTGCAATTAAAAGATTTTTTTAGTCAAAGTTCTTTGTTTGGAGAACAAAGAATTTATGTGATTGAAGA
AATGGAAAAAACAACTTTGCCAGCAGCCAACAGTTTGCTTCATTTTTTAGAAAATACTCCCAATAATATAATTGGTTTTT
TGTTGACAGACAATTTACATCAAGTTTTGACAACAATCGTTTCACGTTGTCAAGTTATCAATATTGATGTTTTCAAACAA
CAGTTATTAACTCCTGCAATCGAAGAACGAAAATTATCGCAAGAAATAGATGTTATGAATTGTGCTTTAATTCCTTTGAT
AAATATTTCTTCTGACGAAAATACAGCTTATTATCTAGAATTTAAAAAATATTTTTTGTTTTTTTTGGAACAATTTCCTA
AAGATGGTTCTTGTGCAACTTATGACTTTGCTACTGTTCTTATAAATTCTTTTGCTGTTTTTTTAAGCGATTTGGTATCA
GTTTTGTTAAGGTGGTTTTTAGATTTGTTTTATCAAAAAAAACAATTGCCTATTTATTTTGAAAATCAAGCACACCATCA
AAAGGAATTTCAAAATTTAACTTTACAGCGAATCACAAATATTTTAGAGATTCTGCAAAAATATCATCAAGAAAAAATTA
ATTTGGTGAATCCCCAAAACCTCTTTTTTGCTTTAATTTTGGAATTAGAACAACAAAAATATTTTTAA

Upstream 100 bases:

>100_bases
AACTGGCCCAAAAAGAAAATAAACGTATTATCAAAATTCAAGCAGATAATTCTTTGCCTCAATTATCTTCTTTAATTTAC
CAAAAAGTTAAACATTTATT

Downstream 100 bases:

>100_bases
TAATTTTTTTAATCAAGGAGGCAATATGTTATTTCACCAAAAAAGTTTTTGCAATCAAAAACCGACTTTGTATTTAGTTG
CAACTCCTATCGGTAATTTG

Product: DNA polymerase III, delta prime subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPNQPFLKPFLKIIQNKKLAHLYLITGLDLPQRKKFVLELSYQILKSQENTQNHSFLKQTLTEGTYPNFYYLKKDNHLFK
KEQILQLKDFFSQSSLFGEQRIYVIEEMEKTTLPAANSLLHFLENTPNNIIGFLLTDNLHQVLTTIVSRCQVINIDVFKQ
QLLTPAIEERKLSQEIDVMNCALIPLINISSDENTAYYLEFKKYFLFFLEQFPKDGSCATYDFATVLINSFAVFLSDLVS
VLLRWFLDLFYQKKQLPIYFENQAHHQKEFQNLTLQRITNILEILQKYHQEKINLVNPQNLFFALILELEQQKYF

Sequences:

>Translated_315_residues
MPNQPFLKPFLKIIQNKKLAHLYLITGLDLPQRKKFVLELSYQILKSQENTQNHSFLKQTLTEGTYPNFYYLKKDNHLFK
KEQILQLKDFFSQSSLFGEQRIYVIEEMEKTTLPAANSLLHFLENTPNNIIGFLLTDNLHQVLTTIVSRCQVINIDVFKQ
QLLTPAIEERKLSQEIDVMNCALIPLINISSDENTAYYLEFKKYFLFFLEQFPKDGSCATYDFATVLINSFAVFLSDLVS
VLLRWFLDLFYQKKQLPIYFENQAHHQKEFQNLTLQRITNILEILQKYHQEKINLVNPQNLFFALILELEQQKYF
>Mature_314_residues
PNQPFLKPFLKIIQNKKLAHLYLITGLDLPQRKKFVLELSYQILKSQENTQNHSFLKQTLTEGTYPNFYYLKKDNHLFKK
EQILQLKDFFSQSSLFGEQRIYVIEEMEKTTLPAANSLLHFLENTPNNIIGFLLTDNLHQVLTTIVSRCQVINIDVFKQQ
LLTPAIEERKLSQEIDVMNCALIPLINISSDENTAYYLEFKKYFLFFLEQFPKDGSCATYDFATVLINSFAVFLSDLVSV
LLRWFLDLFYQKKQLPIYFENQAHHQKEFQNLTLQRITNILEILQKYHQEKINLVNPQNLFFALILELEQQKYF

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37301; Mature: 37170

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNQPFLKPFLKIIQNKKLAHLYLITGLDLPQRKKFVLELSYQILKSQENTQNHSFLKQT
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LTEGTYPNFYYLKKDNHLFKKEQILQLKDFFSQSSLFGEQRIYVIEEMEKTTLPAANSLL
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCHHHHHH
HFLENTPNNIIGFLLTDNLHQVLTTIVSRCQVINIDVFKQQLLTPAIEERKLSQEIDVMN
HHHHCCCCCEEEEEECCCHHHHHHHHHHHCEEECHHHHHHHHHCHHHHHHHHHHHHHHHH
CALIPLINISSDENTAYYLEFKKYFLFFLEQFPKDGSCATYDFATVLINSFAVFLSDLVS
HHHEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VLLRWFLDLFYQKKQLPIYFENQAHHQKEFQNLTLQRITNILEILQKYHQEKINLVNPQN
HHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LFFALILELEQQKYF
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNQPFLKPFLKIIQNKKLAHLYLITGLDLPQRKKFVLELSYQILKSQENTQNHSFLKQT
CCCCHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LTEGTYPNFYYLKKDNHLFKKEQILQLKDFFSQSSLFGEQRIYVIEEMEKTTLPAANSLL
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCHHHHHH
HFLENTPNNIIGFLLTDNLHQVLTTIVSRCQVINIDVFKQQLLTPAIEERKLSQEIDVMN
HHHHCCCCCEEEEEECCCHHHHHHHHHHHCEEECHHHHHHHHHCHHHHHHHHHHHHHHHH
CALIPLINISSDENTAYYLEFKKYFLFFLEQFPKDGSCATYDFATVLINSFAVFLSDLVS
HHHEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
VLLRWFLDLFYQKKQLPIYFENQAHHQKEFQNLTLQRITNILEILQKYHQEKINLVNPQN
HHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LFFALILELEQQKYF
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]