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The map label for this gene is infC [H]

Identifier: 197294237

GI number: 197294237

Start: 106478

End: 106912

Strand: Direct

Name: infC [H]

Synonym: PAa_0095

Alternate gene names: 197294237

Gene position: 106478-106912 (Clockwise)

Preceding gene: 197294236

Following gene: 197294238

Centisome position: 12.1

GC content: 26.67

Gene sequence:

>435_bases
TTGGGTATTTTTGACCAAAATGAAGCCTTGAAATTATCAGAAAAAAAAGAAATTGATATTGTAGTAGTTAACGCTGATTC
AACACCTATGGTTGCTCGTTTGATGGATTATCAAAAACATCGTTATAACCAACAAAAAAAACATCGCGAAGACAAAAAAA
AATCTCAAGTGAGTGTTTTAAAAGAAATCAGAATTAGTCCAAATATTGATATTAATGATTTAAACACGAAATTAAAACAA
ATGCAAAAGTTTTTAAAACAAGGAGATAAAGTGAAAATTAGCATGCGTTTTCGTGGTCGAATGATTAATAATTCTCAATT
AGGAGAAACGATTTTGAAAAAAATTATTAAAGATTTAAGCAATTTAGCTAACACAGAAAGTCCTTTAAAATTAAAAGGAA
ATCAATTTATAACTGTTTTATCTCCTTTGAAATAA

Upstream 100 bases:

>100_bases
TATTAAATTACCTAAATTTAAAAAAAAATCTAATGTAGATTTATACAATGATCAAATACCGAAGGGTAAATATTTAATTA
TTGATGAAAAAGGAGAAAAG

Downstream 100 bases:

>100_bases
CCAATTTCATTTAAATAGCTTAAAAAAACTAAATTAAAAGTCGTAATTTCTCCAGTAAAGAATCAACTTTATTTTTGTAA
AATCCAGAAAGGAATTAACT

Product: Translation initiation factor IF3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MGIFDQNEALKLSEKKEIDIVVVNADSTPMVARLMDYQKHRYNQQKKHREDKKKSQVSVLKEIRISPNIDINDLNTKLKQ
MQKFLKQGDKVKISMRFRGRMINNSQLGETILKKIIKDLSNLANTESPLKLKGNQFITVLSPLK

Sequences:

>Translated_144_residues
MGIFDQNEALKLSEKKEIDIVVVNADSTPMVARLMDYQKHRYNQQKKHREDKKKSQVSVLKEIRISPNIDINDLNTKLKQ
MQKFLKQGDKVKISMRFRGRMINNSQLGETILKKIIKDLSNLANTESPLKLKGNQFITVLSPLK
>Mature_143_residues
GIFDQNEALKLSEKKEIDIVVVNADSTPMVARLMDYQKHRYNQQKKHREDKKKSQVSVLKEIRISPNIDINDLNTKLKQM
QKFLKQGDKVKISMRFRGRMINNSQLGETILKKIIKDLSNLANTESPLKLKGNQFITVLSPLK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=145, Percent_Identity=41.3793103448276, Blast_Score=106, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 16680; Mature: 16549

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIFDQNEALKLSEKKEIDIVVVNADSTPMVARLMDYQKHRYNQQKKHREDKKKSQVSVL
CCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KEIRISPNIDINDLNTKLKQMQKFLKQGDKVKISMRFRGRMINNSQLGETILKKIIKDLS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCEECCCCHHHHHHHHHHHHHHH
NLANTESPLKLKGNQFITVLSPLK
HHCCCCCCEEECCCEEEEEECCCC
>Mature Secondary Structure 
GIFDQNEALKLSEKKEIDIVVVNADSTPMVARLMDYQKHRYNQQKKHREDKKKSQVSVL
CCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KEIRISPNIDINDLNTKLKQMQKFLKQGDKVKISMRFRGRMINNSQLGETILKKIIKDLS
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCEECCCCHHHHHHHHHHHHHHH
NLANTESPLKLKGNQFITVLSPLK
HHCCCCCCEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA